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AcuteKidneyInjury

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Acute Kidney Injury AKI Acute kidney failure, renal failure. Patient | Patient

acute renal failure' (ARF); Acute kidney injury (AKI) or acute kidney failure information available. Treat acute kidney injury AKI and problems with kidney functions and renal issues  
Patient.co.uk
over 4 years ago
5
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How does acute renal failure cause anemia?

How do the two relate to each other? Is the anemia hemolytic, or hypovolemic? Is it the presence of hematuria that causes anemia, could it be severe enough to do so?  
Aerosus 2
over 6 years ago
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Critical Care

Fluid administration is a first-line therapy for acute kidney injury associated with circulatory failure. Although aimed at increasing renal perfusion in these patients, this intervention may improve systemic hemodynamics without necessarily ameliorating intrarenal flow distribution or urine output. We used Doppler techniques to investigate the effects of fluid administration on intrarenal hemodynamics and the relationship between changes in renal hemodynamics and urine output. We hypothesized that, compared to systemic hemodynamic variables, changes in renal hemodynamics would better predict increase in urine output after fluid therapy.  
ccforum.com
over 4 years ago
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Clinical Cases and Images: Nonsteroidal Antiinflammatory Drugs (NSAIDs)-Induced Acute Renal Failure

Renal failure with nsaids is an entity which is rarely seen these days, partly due to more awareness of the side effects of these drugs and partly because of the emergence of novel, safe painkillers. acute renal failure caused by NSAIDS is rarer still and one should be cautious while making this diagnosis. a lot of other agents and simultaneous medications which the patient is taking is usually the cause.  
clinicalcases.org
about 4 years ago
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Incidences and clinical outcomes of acute kidney injury in ICU: a prospective observational study in Sri Lanka

Acute kidney injury (AKI) is a common and a serious complication among patients admitted to intensive care units (ICUs), and has been the focus of many studies leading to recent advances in diagnosis and classification. The incidence and outcome of AKI in Sri Lankan ICUs is largely unknown. The aim of this study was to describe the incidence, severity and outcome of AKI among patients admitted to the medical ICU, National Hospital, Colombo, Sri Lanka (NHSL).  
biomedcentral.com
about 4 years ago
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Critical Care

Saline-based and hydroxyethyl starch solutions are associated with increased risk of renal dysfunction. In the present study, we tested the hypothesis that balanced solutions and a limited volume of hydroxyethyl starch solution (renal protective fluid management [RPF] strategy) would decrease the incidence of postoperative acute kidney injury (AKI) and improve clinical outcomes in patients undergoing off-pump coronary artery bypass graft surgery (OPCAB).  
ccforum.com
about 4 years ago
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Acute kidney injury: prevention, detection and management | Guidance and guidelines | NICE

This clinical guideline offers evidence-based advice on the prevention, detection and management of acute kidney injury up to the point of renal replacement therapy.  
nice.org.uk
almost 4 years ago
12ecd9d06195967a09f5ae0171ec109c189158fb741452446708492
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Acute Kidney Injury

Causes, treatment, and classification of AKI  
Mrs Malaika Smith
over 3 years ago
7
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Why can we see a sharp demarcation between the cortex and the medulla in shock kidney?

Why can we see a sharp demarcation between the cortex and the medulla in shock kidney? What is the pathomechanism that govern the process of acute renal failure that causes that morphological sign? Thank you all.  
amir zur
almost 7 years ago
Www.bmj
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Acute kidney injury alerts should be used to draw clinicians’ attention to severe illness

Sawhney makes the important point that the number of acute kidney injury alerts will be determined by how the baseline is defined and the level of change needed to exceed a somewhat arbitrary cut-off point.1 He highlights the difficulty of defining the baseline and …  
feeds.bmj.com
over 4 years ago
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'Preventable acute kidney injury deaths could end by 2025'

Experts call for an end to preventable acute kidney injury deaths within the next 10 years, while another study suggests that kidney failure is being undertreated worldwide.  
medicalnewstoday.com
over 4 years ago
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Protecting heart surgery patients' kidney health with high-dose statin

Acute kidney injury often arises after major surgery because the kidneys can be deprived of normal blood flow during the procedure.  
medicalnewstoday.com
over 4 years ago
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Episode 21 – Acute Kidney Injury

(ITUNES OR LISTEN HERE) The Free Open Access Medical Education (FOAM) Dr. Josh Farkas of the PulmCrit blog has produced a couple of blog posts on the importance of renal protection in sepsis, Renoresuscitation: Sepsis resuscitation designed to avoid long-term complications and Renal microvascular hemodynamics in sepsis: a new paradigm.  Much of this is theoretical and certainly not…  
foamcast.org
over 4 years ago
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Critical Care

Postoperative acute kidney injury (AKI) is a frequently observed phenomenon after cardiac surgery with cardio-pulmonary bypass (CPB); this severe complication is associated with adverse patient outcomes. There are multiple mechanisms involved in AKI during cardiac surgery, including CPB-dependent hemolysis. An IV infusion of sodium bicarbonate, which leads to urine alkalization, may play a role in preventing AKI. Recently, several trials have investigated the effect of sodium bicarbonate and reported controversial results. The purpose of this investigation was to investigate the following question. Under what circumstances can sodium bicarbonate prevent postoperative AKI?  
ccforum.com
over 4 years ago
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Critical Care

Children admitted to a pediatric intensive care unit (ICU) are at high risk of developing acute kidney injury (AKI). Although serum creatinine (SCr) levels are used in clinical practice, they are insensitive for early diagnosis of AKI. Urinary neutrophil gelatinase-associated lipocalin (uNGAL) and kidney injury molecule-1 (KIM-1) are novel AKI biomarkers whose performance in pediatric ICU patients is largely unknown. In this study, we aimed to characterize uNGAL and KIM-1 patterns in children following ICU admission and to assess their properties in relation to identifying children at risk for AKI development.  
ccforum.com
over 4 years ago
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Critical Care

The Surviving Sepsis Campaign [1] advocates maintaining a mean arterial pressure (MAP) of at least 65 mm Hg in sepsis patients undergoing resuscitation. Leone and colleagues [2], in an article published in this journal, suggest considering higher MAP targets in the resuscitation of patients with a history of arterial hypertension so they do not progress to acute kidney injury. Asfar and colleagues [3], in a multicenter, open-label trial, showed no significant difference in mortality outcomes in septic shock patients undergoing resuscitation with an MAP target of either 80 to 85 mm Hg (high-target group) or 65 to 70 mm Hg (low-target group). However, the study did show that chronic hypertensive patients in the higher-target group had lower incidences of acute kidney injury and renal replacement therapy. This likely stems from the need for higher MAPs in chronic hypertensive patients in order to maintain organ blood flow because of a shift of the organ’s autoregulatory range to the right. Thus, targeting a higher MAP for chronic hypertensive patients may help avoid the development of acute kidney injury and the need for renal replacement therapy. Renal replacement therapy carries with it inherent morbidity as well as additional cost. These costs include the need for dialysate fluid and extra personnel and the use of anticoagulation and the extracorporeal circuit [2]. However, chronic hypertensive patients in the high-target group had a greater incidence of new-onset atrial fibrillation (5.2% in the low-target group versus 9% in the high-target group). Patients with new-onset atrial fibrillation during sepsis have been shown to have increased incidences of in-hospital stroke and in-hospital mortality [4] as well as subsequent recurrence of atrial fibrillation and increased long-term risks for heart failure, ischemic stroke, and death [5]. This may offset any benefit of a higher MAP. The ideal target MAP may have to be individualized for specific patient populations. More studies are needed to determine whether baseline blood pressure plays a role in the ultimate determination of the ideal MAP target for patients with sepsis.  
ccforum.com
over 4 years ago
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Critical Care

Neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys-C), and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) are novel diagnostic biomarkers of acute kidney injury (AKI). We aimed to determine the diagnostic properties of these biomarkers for detecting AKI in critically ill patients with sepsis.  
ccforum.com
over 4 years ago
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Critical Care

Acute Kidney Injury (AKI) is common in critical ill populations and its association with high short-term mortality is well established. However, long-term risks of death and renal dysfunction are poorly understood and few studies exclude patients with pre-existing renal disease, meaning outcome for de novo AKI has been difficult to elicit. We aimed to compare the long-term risk of Chronic Kidney Disease (CKD), End Stage Renal Disease (ESRD) and mortality in critically ill patients with and without severe de novo AKI.  
ccforum.com
over 4 years ago
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Acute Kidney Injury: Pearls and Pitfalls - emdocs

Learn the latest tips and resources when dealing with acute kidney injury (AKI) via the KDIGO group. Enjoy!  
emdocs.net
over 4 years ago