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Microrobots to Drill Through Blocked Arteries (VIDEO) |

Researchers at Drexel University have developed microscopic "swimmers" that may one day be used to break up blood vessel occlusions. Currently, such treatm  
medgadget.com
about 5 years ago
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Novel oral anticoagulants for the treatment of deep vein thrombosis | Cochrane

Deep vein thrombosis (DVT) is a condition in which a blood clot forms in the deep vein of the leg or pelvis. It affects approximately 1 in 1000 people. If it is not treated, the clot can travel in the blood and block the arteries in the lungs. This life-threatening condition is called a pulmonary embolism (PE) and occurs in approximately 3 to 4 per 10,000 people. The chances of getting a DVT can be increased if people have certain risk factors. These include previous clots, prolonged periods of immobility (such as travelling on aeroplanes or bed rest), cancer, exposure to oestrogens (pregnancy, oral contraceptives or hormone replacement therapy), trauma and blood disorders such as thrombophilia (abnormal blood clotting). A DVT is diagnosed through determining the risk factors and performing an ultrasound of the leg veins. If a DVT is confirmed, people are treated with an anticoagulant. This medicine prevents further clots from forming. Until recently, the drugs of choice were heparin, fondaparinux and vitamin K antagonists. However, these drugs can cause side effects and have limitations. Two further classes of novel oral anticoagulants have been developed: these are called direct thrombin inhibitors (DTI) and factor Xa inhibitors. There are particular reasons why oral DTIs and factor Xa inhibitors might now be better medicines to use. They can be given orally, they have a predictable effect, they do not require frequent monitoring or re-dosing and they have few known drug interactions. This review measures the effectiveness and safety of these new drugs with conventional treatment.  
cochrane.org
about 5 years ago
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Dressings and topical agents for arterial leg ulcers | Cochrane

People with blood circulation problems in their legs can develop leg ulcers. The majority of ulcers result from poor blood flow in the veins and are treated by compression. Arterial leg ulcers occur because of poor blood supply to the legs when there is a block in a leg artery or narrowing of the arteries (atherosclerosis). Without treatment of the underlying poor arterial blood supply, ulcers take a long time to heal or may never heal. These ulcers are treated by covering them with dressings, or using creams or ointments (topical agents), or both to promote healing and protect the ulcers from infection. A variety of types of dressings can be used depending on the overall aim of the treatment. The intention is to select dressings to reduce ulcer pain, manage exudate if present (the fluid that can leak from these ulcers) and promote healing.  
cochrane.org
about 5 years ago
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Medical adjuvant treatment to increase the patency of arteriovenous fistulae and grafts used for renal dialysis | Cochrane

People with advanced kidney disease (end-stage renal disease) need dialysis to perform kidney functions. In haemodialysis, blood is filtered through a machine. To allow a large enough passage for blood to flow between the person and the machine, an artery and a vein can be surgically joined (to form an arteriovenous fistula) or an artificial graft (a substitute for a vein) is used to join the artery to the vein. These access points might last for years but can become blocked or infected. This review investigates if additional medical therapy can keep these dialysis access points functioning.  
cochrane.org
about 5 years ago
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Critical Care

Patients receiving circulatory support with peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) are at risk of developing differential hypoxia. This phenomenon occurs in patients with concomitant respiratory failure. Poorly oxygenated blood, ejected into the ascending aorta from the left ventricle, competes with retrograde flow from the ECMO circuit, potentially causing myocardial and cerebral ischaemia. In a recent Critical Care article, Hou et al. use an animal model of peripheral VA-ECMO to study the physiology of differential hypoxia. Their findings support a dual circuit hypothesis, and show how different cannulation strategies can disrupt the two circuits. In particular, strategies that increase venous oxygen saturations in the pulmonary artery can have a large effect on oxygenation saturation in the ascending aorta. The authors provide evidence supporting the use of veno-arterial-venous ECMO in patients who require peripheral VA-ECMO but have simultaneous respiratory failure.  
ccforum.com
about 5 years ago
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Does hyperbaric oxygen therapy improve outcome after heart attack? | Cochrane

Acute heart attacks and severe angina (heart pain) are usually due to blockages in the arteries supplying the heart (coronary arteries). These problems are collectively referred to as 'acute coronary syndrome' (ACS). ACS is very common and may lead to severe complications including death. Hyperbaric oxygen therapy (HBOT) involves people breathing pure oxygen at high pressures in a specially designed chamber. It is sometimes used as a treatment to increase the supply of oxygen to the damaged heart in an attempt to reduce the area of the heart that is at risk of dying.  
cochrane.org
about 5 years ago
Static.www.bmj
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Delivering thrombectomy for acute stroke using cardiology services

Evidence is mounting for the supplementary benefit over thrombolysis of endovascular therapy in selected patients with acute stroke. Mechanical percutaneous removal of intracerebral clot using an aspiration catheter ensures that the artery is recanalised. Like thrombolysis, the benefits are greater with early treatment, and we need to think about how to achieve this. Evidence on the benefits of rapid primary percutaneous coronary intervention in patients presenting with ST segment elevation myocardial infarction (STEMI) led to a network being set up in the United Kingdom to provide 24 hour care.1 Teams staffing these networks, skilled in opening arteries quickly, could also provide endovascular therapy to selected patients with acute stroke.  
feeds.bmj.com
about 5 years ago
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Chest X ray notice pulmonary artery hypertension

Prepare for USMLE,UK,CANADIAN,AUSTRALIAN, NURSING & OTHER MEDICAL BOARD examinations around the globe with us.Understand the basics, concepts and how to answ...  
youtube.com
about 5 years ago
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The risk of heart attack and stroke in women using birth control pills | Cochrane

Since their introduction, combined oral contraceptive pills have become one of the most popular birth control methods. These pills contain two types of female hormones, estrogen and progestagen. When used correctly, the failure rate (i.e. the occurrence of unwanted pregnancy) is less than one per 100 women per year. Despite their reliability, oral contraceptive pills have been found to increase the risk of a blood clot forming in an artery, i.e. arterial thrombosis (heart attack or stroke). As arterial thrombosis is rare in young women, and as many types of oral contraceptive pills exist, the size of the risk is unclear. Furthermore, the effect of different types of progestagens or different doses of estrogen on the risk of arterial thrombosis is unknown.  
cochrane.org
about 5 years ago
02d9f6b7083906016e4f0acbc69df6a7c3a807c98083793715904726
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Scheme of the main branches out of the aorta

I find it an easy way to study all of the arteries in our body. The name of the arteries are in Latin, but the extra explanation is in Dutch (sorry for that!). If you find any mistakes or tips how to make it better, please put it in the comments, so I can correct them :)  
Elise Ruysschaert
about 5 years ago
4a313a3b22ce2a83aa30f57186610c43a297f6195954271827845352
3
226

Scheme of the arteries of the upper limb

I find it an easy way to study all of the arteries in our body. The name of the arteries are in Latin, but the extra explanation is in Dutch (sorry for that!). If you find any mistakes or tips how to make it better, please put it in the comments, so I can correct them :)  
Elise Ruysschaert
about 5 years ago
2402a44a4b555920b038f61d9bbb3a1f8f2eee346995516775049548
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Scheme of the arteries of the lesser limb

I find it an easy way to study all of the arteries in our body. The name of the arteries are in Latin, but the extra explanation is in Dutch (sorry for that!). If you find any mistakes or tips how to make it better, please put it in the comments, so I can correct them :)  
Elise Ruysschaert
about 5 years ago
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Spontaneous Coronary Artery Dissection | Resus Review

Understanding SCAD including risk factors, triggers, angiographic diagnosis, and deciding between conservative and invasive treatment.  
resusreview.com
about 5 years ago
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Axillary Artery | Flashcard Anatomy

Axillary artery anatomy flashcard. Check out the 3D app at http://AnatomyLearning.com. More videos available on http://AnatomyZone.com. Use this brief flashc...  
youtube.com
about 5 years ago
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New Directions for Treating NSTE-ACS Patients: ESC

The society's 2015 revamped NSTE-ACS guidelines now stress radial-artery vascular access for PCI, allow flexibility in duration of dual-antiplatelet therapy, and make room for 1-hour troponin assays.  
medscape.com
about 5 years ago
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A Compressed Celiac Artery May Lead to High-Risk Surgery

Can you properly manage this rare syndrome, which can be as difficult to identify as it is to treat?  
medscape.com
about 5 years ago
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LCZ696 in HF: 'Cost-effective' but Likely Costly, Says Analysis

Reviewers who found the newly available angiotensin-receptor/neprilysin inhibitor cost-effective by standard criteria were less sure about their similar evaluation of the CardioMEMS pulmonary-artery pressure monitor.  
medscape.com
about 5 years ago
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Tongue Deviation Lesion - Cerebral Artery - GUWS Medical

I. THE OLFACTORY NERVE, the first cranial nerve CN I Figure 13-1 , mediates olfaction smell . It is the only sensory system that has no precortical relay in  
guwsmedical.info
about 5 years ago
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Drug Loaded Nanoparticles Mimic Platelets to Avoid Immune System and Reach Disease Targets |

Pseudocolored scanning electron microscope images of platelet-membrane-coated nanoparticles (orange) binding to the lining of a damaged artery (top) and to  
medgadget.com
about 5 years ago
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Spontaneous Coronary Artery Dissection | Resus Review

Understanding SCAD including risk factors, triggers, angiographic diagnosis, and deciding between conservative and invasive treatment.  
charlesbruen.wpengine.com
about 5 years ago