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What is Rheumatoid Arthritis - The Mount Sinai Hospital

#Rheumatoid #arthritis (RA) affects an estimated 1.5 million adults in the United States, causing stiffness, swelling, pain, and loss of function in the joints. Learn about #symptoms, current treatments, and the newest research. #Health #Medical #Medicine #treatment #HealthyTips #Wellness |Rheumatoid Arthritis, Arthritis and Autoimmune.  
uk.pinterest.com
over 4 years ago
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The use of drugs to manage symptoms in people with arthritis related to cystic fibrosis | Cochrane

Arthritis is not a common complication of cystic fibrosis, but it can be a major complication when it does occur. There are two distinct types of arthritis in cystic fibrosis: cystic fibrosis-related arthropathy and hypertrophic pulmonary osteoarthropathy. The best treatment for these conditions is not clear because of the underlying disease and its intense treatment. We planned to report evidence from clinical studies to evaluate the effectiveness and safety of different anti-inflammatory analgesic drugs compared with placebo, with each other or with no treatment. However, we were disappointed that we could not find any completed randomised controlled studies of these treatments or any evidence from non-randomised controlled studies. One study in cystic fibrosis-related arthropathy has finished and may provide some evidence when published. We suggest that there should be a randomised controlled study to look at the effects and the safety of using anti-inflammatory drugs or painkillers or both to manage the symptoms of cystic fibrosis-related arthritis. This is an update of a previously published review (date of last search 19 January 2016). Since no studies have been included in the review up until January 2016, we will still search for studies every two years, but will not publish an updated version of this review until we can include any new studies.  
cochrane.org
over 4 years ago
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Rheumatoid arthritis, TNF inhibitors, and non-melanoma skin cancer

Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the two most common types of non-melanoma skin cancer. Epidemiological studies have indicated that the incidence of non-melanoma skin cancers is higher in patients with rheumatoid arthritis than in the general population.1 2 Further concerns exist that immunosuppression contributes to an increased prevalence of these malignancies. Specifically, organ transplantation and the concomitant use of immunosuppressive agents is strongly associated with SCC and to a lesser extent with BCC.3 4 Tumor necrosis factor (TNF) inhibitors are the most commonly used biological immunosuppressive agents for treatment of rheumatoid arthritis. Pooled data from 74 randomized controlled trials showed that TNF inhibitors were associated with an increase in risk of non-melanoma skin cancer beyond the risk associated with rheumatoid arthritis alone.5 Several large observational studies have supported this finding,6 7 but others have not.8 9 …  
feeds.bmj.com
over 4 years ago
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Rheumatoid arthritis, TNF inhibitors, and non-melanoma skin cancer

Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the two most common types of non-melanoma skin cancer. Epidemiological studies have indicated that the incidence of non-melanoma skin cancers is higher in patients with rheumatoid arthritis than in the general population.1 2 Further concerns exist that immunosuppression contributes to an increased prevalence of these malignancies. Specifically, organ transplantation and the concomitant use of immunosuppressive agents is strongly associated with SCC and to a lesser extent with BCC.3 4 Tumor necrosis factor (TNF) inhibitors are the most commonly used biological immunosuppressive agents for treatment of rheumatoid arthritis. Pooled data from 74 randomized controlled trials showed that TNF inhibitors were associated with an increase in risk of non-melanoma skin cancer beyond the risk associated with rheumatoid arthritis alone.5 Several large observational studies have supported this finding,6 7 but others have not.8 9 …  
feeds.bmj.com
over 4 years ago
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Rheumatoid arthritis, anti-tumour necrosis factor treatment, and risk of squamous cell and basal cell skin cancer: cohort study based on nationwide prospectively recorded data from Sweden

Objective To investigate the risk of squamous cell and basal cell skin cancer in patients with rheumatoid arthritis naive to biologic drugs, in patients starting tumour necrosis factor (TNF) inhibitor treatment, and in the general population.  
feeds.bmj.com
over 4 years ago
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Rheumatoid arthritis, anti-tumour necrosis factor treatment, and risk of squamous cell and basal cell skin cancer: cohort study based on nationwide prospectively recorded data from Sweden

Objective To investigate the risk of squamous cell and basal cell skin cancer in patients with rheumatoid arthritis naive to biologic drugs, in patients starting tumour necrosis factor (TNF) inhibitor treatment, and in the general population.  
feeds.bmj.com
over 4 years ago
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Gout: Colchicine Linked to Reduced CV Risk

Colchicine use was associated with a 49% lower risk for cardiovascular events and a 73% reduction in all-cause mortality in patients with gout.  
medscape.com
over 4 years ago
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Paracetamol: Ineffective for Spinal Pain and Osteoarthritis

While paracetamol continues to be prescribed as an initial treatment for osteoarthritis and back pain, this comprehensive meta-analysis found little evidence for its use in these conditions.  
medscape.com
over 4 years ago
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Two thirds of rheumatology patients wait too long for assessment, audit finds

Two thirds of patients with early inflammatory arthritis are not seen by a specialist within the recommended three weeks of referral, says a national clinical audit of rheumatoid and early inflammatory arthritis in England and Wales.1  
feeds.bmj.com
over 4 years ago
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Two thirds of rheumatology patients wait too long for assessment, audit finds

Two thirds of patients with early inflammatory arthritis are not seen by a specialist within the recommended three weeks of referral, says a national clinical audit of rheumatoid and early inflammatory arthritis in England and Wales.1  
feeds.bmj.com
over 4 years ago
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Medical, Behavioral Intervention Improves Arthritis Care

A low-intensity combined osteoarthritis patient and provider intervention modestly improved self-reported functional outcome.  
medscape.com
over 4 years ago
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Exercise for Osteoarthritis of the Knee

What benefits does therapeutic exercise offer for those with knee osteoarthritis?  
medscape.com
over 4 years ago
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Rx for Osteoarthritis and Osteoporosis: High-Impact Exercise

Studies show that low-impact exercise can benefit patients with either condition. But new research indicates that, when the disease isn't too severe, high-impact exercise can be even more beneficial.  
medscape.com
over 4 years ago
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FDA Approves Zurampic for Patients With Gout

Zurampic (lesinurad) is approved to treat hyperuricemia associated with gout in combination with a xanthine oxidase inhibitor.  
medscape.com
over 4 years ago
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Osteoarthritis and Frailty in Elderly Individuals in Europe

A new study examines the prevalence of OA and frailty among elderly individuals in European countries -- and explores the possible connection between these two conditions.  
medscape.com
over 4 years ago
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CHMP Recommends Lesinurad (Zurampic) for Gout

The European Medicines Agency panel has recommended marketing authorization for lesinurad for the treatment of hyperuricemia in adults with gout.  
medscape.com
over 4 years ago
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Early Psoriatic Arthritis: Should We Treat it in the Same Way as We Treat Rheumatoid Arthritis?: Abstract and Introduction

Abstract and Introduction: New treatment options for patients with psoriatic arthritis promise more effective therapy.  
medscape.org
over 4 years ago
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Rheumatic fever diagnosis: Jones major criteria | Medical Mnemonics

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lifehugger.com
over 4 years ago
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Psoriatic Arthritis Incidence Higher Than Thought

The incidence of psoriatic arthritis among those with psoriasis is higher than previously thought, and the risk persists over time, a prospective study has found.  
medscape.com
over 4 years ago
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Combo Drug for Arthritis/Hypertension Meets Goal in Study

Kitov Pharmaceuticals Holdings Ltd said on Tuesday its lead drug, KIT-302, met the main goal of a late-stage study, reducing pain without increasing the risk of heart diseases in patients with osteoarthritis.  
medscape.com
over 4 years ago