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Use of Pressurized Metered-Dose Inhalers for Asthma

When using a pressurized metered-dose inhaler, how does improper technique affect the dose delivered?  
medscape.com
almost 5 years ago
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Leukotriene-Receptor Antagonists Improve Asthma Control

Leukotriene-receptor antagonists, alone or with inhaled corticosteroids, significantly improved asthma control and reduced exacerbations, according to a systematic review.  
medscape.com
almost 5 years ago
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Asthma: Secondhand Smoke Doubles Kids' Hospitalization Risk

Exposure to smoking in the home has been linked to a nearly twofold increase risk for asthma exacerbation requiring hospitalization in children with asthma.  
medscape.com
almost 5 years ago
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CHMP Backs Mepolizumab for Severe Eosinophilic Asthma

The European Medicines Agency committee recommended approval of the novel anti-IL-5 biologic as add-on maintenance treatment in adults with severe refractory eosinophilic asthma.  
medscape.com
almost 5 years ago
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magnesium-for-asthma

Thanks to Dr. Kim for the writeup of this post Case A 36-year-old female with a history of asthma presents with wheezing, tachypnea, and a room air O2 Saturation of 90%. Her albuterol and flovent inhalers failed to control her symptoms at home. Her auscultatory exam reveals bilateral diffuse wheezing. She is afebrile, normotensive, and…  
tjuhem.wordpress.com
almost 5 years ago
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Reslizumab Works Best in Late-Onset Eosinophilic Asthma

A new analysis of phase 3 data shows that the anti-interleukin-5 antibody is more effective in patients older than 40 years.  
medscape.com
almost 5 years ago
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Pulse oximeters used to self monitor oxygen saturation levels as part of a personalised asthma action plan for people with asthma | Cochrane

We became aware through talking with people with asthma that some are using pulse oximeters to monitor their own blood oxygen levels during an asthma attack. Pulse oximeters are marketed by some suppliers as essential equipment for the home medicine cabinet. We wanted to find out if reliable evidence is available on use of pulse oximeters to self monitor asthma exacerbations at home. We decided to include only trials that used pulse oximeters as part of a personalised asthma action plan because it is important that decisions are made on the basis of symptoms as well as oxygen saturation, and that patients have a clear protocol to follow when their asthma worsens.  
cochrane.org
almost 5 years ago
Is 150930 gut microbiomes bacteria 800x600
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Gut Bacteria Disparities Offer Clues to Asthma Etiology

Children at the highest risk for asthma had a lower abundance of four bacteria in their gut in their first 3 months of life, a critical period that may offer future opportunities for prevention.  
medscape.com
almost 5 years ago
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'Good bacteria' key to stopping asthma - BBC News

Being exposed to "good bacteria" early in life could prevent children developing asthma, say US scientists.  
bbc.co.uk
almost 5 years ago
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Asthma steroids 'could stunt growth' - BBC News

Young children given asthma medication before the age of two may not grow to their full height in later life, a preliminary report suggests.  
bbc.co.uk
almost 5 years ago
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Critical Asthma Patient: Pearls/Pitfalls of Management - emdocs

You've tried your normal asthma treatment pathway, and it's not working... What's next?  
emdocs.net
almost 5 years ago
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H3K18 Acetylation in Epithelial Cells of Asthmatic Subjects

What's the interaction between histone modifications and gene regulation in asthma?  
medscape.com
almost 5 years ago
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Dexamethasone vs Prednisone in Pediatric Asthma

Is there any difference in using dexamethasone vs prednisone/prednisolone to treat hospitalized children with asthma?  
medscape.com
almost 5 years ago
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What is the evidence for benefit from leukotriene receptor antagonists in pre-school children who wheeze when they have a cold? | Cochrane

Acute episodes of wheezing in pre-school aged children are common. Many children in this age group seem to wheeze only when they have a common cold-type virus with no ongoing symptoms between episodes, unlike older children with allergic-type asthma. Acute episodes of wheezing cause the child to breathe more quickly than normal and they may require supportive treatment such as the use of rescue inhalers; in moderate or severe episodes they may also need a short course of oral steroids and not uncommonly may require treatment in hospital and supplemental oxygen. Their carers may need to take time off work to look after children who are unwell. Although episodic wheezing with viruses is a common problem, there is controversy about the best way to prevent or shorten episodes.  
cochrane.org
almost 5 years ago
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Core EM: Life-Threatening Asthma - emdocs

A great post by Core EM - Bringing core EM content to anyone, anywhere, anytime. Learn the simplified and point-to-point review of life-threatening asthma by Dr. Anand Swaminathan, MD (@EMSwami)  
emdocs.net
almost 5 years ago
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Early Respiratory Infections and the Development of Asthma

Could preventing respiratory infections in childhood reduce the development of asthma in children and young adults?  
medscape.com
almost 5 years ago
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DFTB in EMA #3 – Easing the Wheeze – Don't Forget the Bubbles

Wheezing children commonly present to the ED. Bronchiolitis, preschool wheeze and asthma are common causes of such presentations. It is important to note that the term ‘wheeze’ is frequently misused by parents to describe a number of respiratory noises, including transmitted upper airway sounds and stridor.[1] Wheeze is, in itself, a symptom manifested by ‘a continuous whistling sound during breathing that suggests narrowing or obstruction in some part of the respiratory airways’.[2] One British study reported that 29.3% of children have had a wheeze by the age of three, and 30% of preschoolers with recurrent wheeze are diagnosed with asthma by 6 years of age.[3, 4] This article briefly reviews the diagnosis and management of preschool wheeze, while considering recent guidelines on bronchiolitis and asthma.  
dontforgetthebubbles.com
almost 5 years ago
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Quality of Life Measure for Older Adolescents With Asthma

This quality of life instrument incorporates substance use, which is an important factor to consider when assessing HRQL in adolescents with asthma.  
medscape.com
almost 5 years ago
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The Airsonett temperature-controlled laminar airflow device for persistent allergic asthma | Advice | NICE

NICE has developed a Medtech Innovation Briefing (MIB) on the Airsonett temperature-controlled laminar airflow device for persistent allergic asthma.  
nice.org.uk
almost 5 years ago
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Persistence of Asthma Following Allergen Avoidance and ProTh2

Find out more about the molecular mechanisms underlying persistent abnormal dendritic cell function and asthma.  
medscape.com
almost 5 years ago