Antibiotics to prevent infection of the brain coverings (meningitis) in patients with basilar skull fracture | Cochrane
Basilar skull fracture (7% to 15.8% of all skull fractures) places the central nervous system in contact with bacteria from the nose and throat and may be associated with cerebrospinal fluid leakage (occurring in 2% to 20.8% of patients). Blood or watery discharge from the nose or ears, bruising behind the ear or around the eyes, hearing loss, inability to perceive odours or facial asymmetry may lead physicians to the diagnosis of basilar skull fracture. Patients with a basilar skull fracture may develop meningitis and some doctors give antibiotics in an attempt to reduce this risk.
over 5 years ago
Severe combined immunodeficiency (SCID) represents a group of rare, sometimes fatal, congenital disorders characterized by little or no immune response. The defining feature of SCID, commonly known as "bubble boy" disease, is a defect in the specialized white blood cells (B- and T-lymphocytes) that defend us from infection by viruses, bacteria and fungi. Without a functional immune system, SCID patients are susceptible to recurrent infections such as pneumonia, meningitis and chicken pox, and can die before the first year of life. Though invasive, new treatments such as bone marrow and stem-cell transplantation save as many as 80% of SCID patients.
over 5 years ago
Which bacteria could cause urinary tract infections but would not show up on a normal urine culture?
Some bacteria species (such as Mycoplasma) are difficult to culture using standard methods. Could these bacteria cause a urinary tract infection in the absence of a positive urine culture? If so, how can these infections be diagnosed in a patient with only general symptoms of cystitis? What other hard-to-culture species besides Mycoplasma can cause urinary tract infections?
about 8 years ago