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Calcium, Vitamin D and bone density

 
almostadoctor.com - free medical student revision notes
over 5 years ago
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Calcium

Calcium See also: Calcium, Vitamin D and Bone Density Parathyroid Glands   Calcium is involved with: Contraction of skeletal, cardiac and smooth muscle Blood clotting  
almostadoctor.com - free medical student revision notes
over 5 years ago
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119

Femoral neck fracture | Radiology Reference Article | Radiopaedia.org

Neck of femur fractures (NOF) are common injuries sustained by older patients who are both more likely to have unsteadiness of gait and reduced bone mineral density, predisposing to fracture. Elderly osteoporotic women are at greatest risk.Epidemi...  
radiopaedia.org
almost 5 years ago
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38

Preterm birth and the role of neuroprotection

Preterm birth remains a common complication of pregnancy and causes substantial neonatal morbidity and mortality. As improvements in the care of preterm neonates have outpaced efforts to prevent preterm birth, the numbers of survivors with neurologic sequelae that affect quality of life have increased. The main strategies to reduce the impact of neurologic complications of prematurity include prevention of preterm birth and protection of the developing fetal brain through antenatal administration of drugs. These strategies rely on a basic understanding of the intertwined pathophysiology of spontaneous preterm labor and perinatal brain injury, which will be reviewed here. The review will outline current methods for the prevention of prematurity and neuroprotection. The use of magnesium sulfate as a neuroprotective compound will be discussed, including concerns over its association with increased pediatric mortality and abnormalities in bone density.  
bmj.com
over 4 years ago
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Zoledronic acid increases bone density but does not reduce fractures in frail elderly people, study finds

A single intravenous dose of the osteoporosis drug zoledronic acid has been found to increase bone mineral density in a group of frail elderly women living in nursing homes and long term care facilities, but it did not reduce the incidence of fractures over a two year period.  
feeds.bmj.com
over 4 years ago
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Bone mineral density improved in frail elderly women treated with zoledronic acid

A single intravenous dose of the osteoporosis drug zoledronic acid improved bone mineral density in a group of frail elderly women living in nursing homes and long-term-care facilities...  
medicalnewstoday.com
over 4 years ago
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Low Bone Density, Carotid Atherosclerosis Linked to SLE

Study finds doubling of odds of carotid plaque, especially in older women.  
medpagetoday.com
over 4 years ago
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Critical Care

We read with great interest the pilot study on fracture risk in 46 critically ill patients by Rawal and colleagues [1]. Bone mineral density (BMD) was assessed with portable calcaneal dual X-ray absorptiometry (DXA) on days 1 and 10. The authors found no overall change in BMD, but increased fracture risk in the subgroup with 'ARDS' (acute respiratory distress syndrome) (n = 34). There are several serious methodological problems: it is unclear if the group assignment is valid as only one of the four Berlin definition criteria [2] for the diagnosis of ARDS is given: oxygenation (no information on timing, chest imaging and origin of the edema). Although peripheral DXA devices are certainly an interesting option for BMD in critically ill and other patients [3], precision errors supplied by the manufacturer should not be used. In fact, each center must determine its (own) precision error and least significant change, which is also operator dependent [4]. The manufacturer stated a 0.9 % coefficient of variation, which is not necessarily applicable to the study setting where it remains unclear how the measurements were performed. This could be an important limitation. Hence, it is unlikely that a 2 % BMD change within such a short time frame as described would reflect anything else other than random variability. Lastly, it is also unclear what the described statistical difference refers to - it should be noted that the smaller subgroup (n = 12) numerically increased their BMD. Undoubtedly, fracture risk following critical illness is a very important topic that requires further high-quality studies [5].  
ccforum.com
over 4 years ago
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Hormonal birth control and fracture risk in observational studies | Cochrane

When bone mass declines with age, the risk of fractures increases. Birth control methods that have hormones may lead to changes in women’s bone density. Worry about fractures may limit the use of these effective methods. Observational studies can collect data on birth control use as well as fractures later in life. Through June 2015, we searched for such studies in several databases.   
cochrane.org
about 4 years ago
Is 150910 hip pelvis x ray 800x600
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FDA Strengthens Fracture Warning for Canagliflozin

New clinical trial data for canagliflozin confirmed previously noted risk about fractures and reduced bone mineral density in the hip and spine, prompting the FDA to revise the product label.  
medscape.com
about 4 years ago
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Vitamin D, Calcium, Exercise Slow Bariatric-Surgery Bone Loss

"We have to implement…dietary recommendations and physical exercise…to avoid this rapid and ongoing decline" in bone density following bariatric weight-loss surgery, an expert urges.  
medscape.com
almost 4 years ago
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Heel Bone Density Lower After ACL Injury/Repair in Adolescence

Adolescent boys with an anterior cruciate ligament (ACL) repair may be at risk for lower bone mineral density (BMD) of the calcanei and associated fracture, according to a new study.  
medscape.com
almost 4 years ago
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New Tenofovir Regimen ECF/TAF -- Advantages and Similarities

Dr Paul Sax explains how this next-generation tenofovir can simplify therapy while potentially avoiding the negative outcomes of renal toxicity and reduced bone density.  
medscape.com
over 3 years ago
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Nonosteoporotic Bone Density and Fractures in Women

When should treatment be initiated in patients with osteopenia? This study sought to determine what effect the transitioning to lower categories of osteopenia had on subsequent fracturing.  
medscape.com
over 3 years ago
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Stimulant Use Tied to Reduced Bone Density in Kids With ADHD

Bone health should be monitored in kids prescribed stimulants for treating ADHD, new research indicates.  
medscape.com
over 3 years ago
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Surgery for hyperparathyroidism is associated with reduced fracture risk

Surgery to remove the parathyroid is associated with a reduced risk of fractures in patients with primary hyperparathyroidism, an observational study in Annals of Internal Medicine has found.1 The researchers also found that treatment with bisphosphonate was associated with increased bone mineral density but not fewer fractures.  
feeds.bmj.com
over 3 years ago
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Milk Allergy Tied to Lower Bone Density in Children

BMD and calcium intake were lower in prepubertal children with persistent cow's milk allergy compared with their peers, a new study has found.  
medscape.com
over 3 years ago
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Abaloparatide May Boost BMD in Older Women With Osteoporosis

The investigational drug abaloparatide may help postmenopausal women increase their bone mineral density (BMD) and reduce their risk of fracture, new industry research suggests.  
medscape.com
over 3 years ago