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Endovascular treatment for stroke

Shortly after a clot occludes a cerebral artery, cells in the infarct core—the most severely ischaemic area—start dying. The tissue surrounding the ischaemic core, the penumbra, is hypoperfused and at risk of progressing to infarction over minutes to hours, depending on the degree of ischaemia. The goal of treatment for acute stroke is to restore blood flow to these potentially salvageable areas as soon as possible. Thrombolysis is traditionally used, but in this issue Rodrigues and colleagues (doi:10.1136/bmj.i1754) summarise the evidence supporting mechanical thrombectomy.1  
feeds.bmj.com
over 4 years ago
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Endovascular treatment for stroke

Shortly after a clot occludes a cerebral artery, cells in the infarct core—the most severely ischaemic area—start dying. The tissue surrounding the ischaemic core, the penumbra, is hypoperfused and at risk of progressing to infarction over minutes to hours, depending on the degree of ischaemia. The goal of treatment for acute stroke is to restore blood flow to these potentially salvageable areas as soon as possible. Thrombolysis is traditionally used, but in this issue Rodrigues and colleagues (doi:10.1136/bmj.i1754) summarise the evidence supporting mechanical thrombectomy.1  
feeds.bmj.com
over 4 years ago
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Gene editing 'boosts' cancer-killing cells - BBC News

Cancer scientists have genetically modified the immune system to help them attack tumours in mice.  
bbc.co.uk
over 4 years ago
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Understanding How Cancer Spreads, and How It May Be Stopped

The latest findings on how cancer cells metastasize from primary to distant sites are highlighted in a special edition of the journal Science.  
medscape.com
over 4 years ago
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Drug Ferrying Nanoparticles Report Back While Killing Cancer Cells |

Cancer therapies have a pernicious way of being effective only for a subset of people suffering from a particular manifestation of the disease. Because the  
medgadget.com
over 4 years ago
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EU Expands Nivolumab Approval For Lung and Kidney Cancer

Nivolumab is now approved in Europe for both nonsquamous- and squamous-type non-small-cell lung cancer, as well as for use in renal cell carcinoma.  
medscape.com
over 4 years ago
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Immunosuppressive Medications and Squamous Cell Carcinoma

How do immunosuppressive medications impact the risk of developing squamous cell skin carcinoma after organ transplantation?  
medscape.com
over 4 years ago
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1

Distinguishing SLE and Fibromyalgia by Complement Activation

Read how testing for cell-bound complement activation products can help establish an accurate diagnosis for SLE.  
medscape.com
over 4 years ago
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1

Biopen Used to Deposit Stem Cells, Repair Tissue Within Joints |

Stem cells have the capacity to be used to reconstruct and repair native tissues, but to apply them so that they survive and live on in their new home can  
medgadget.com
over 4 years ago
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Genomic Differences Underlie Racial Disparities in Renal Cell Carcinoma

Genomic differences in clear cell renal cell carcinomas (ccRCCs) from African American and white patients may contribute to the worse outcomes of African American patients, researchers have reported.  
medscape.com
over 4 years ago
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Erasure With MM4-401 Aids Reprogramming of Murine Stem Cells

MLL1 inhibition by the small-molecule inhibitor MM-401 prompts stem cells in mice to return to "be anything" pluripotence, according to research conducted at the University of Michigan, Ann Arbor.  
medscape.com
over 4 years ago
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Study Suggests Bringing Back Whole-Cell Pertussis Vaccine

Using a mixed vaccine series with whole-cell and Tdap could reduce pertussis incidence dramatically. But would parents accept the old vaccine with its associated adverse effects?  
medscape.com
over 4 years ago
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Twickenham leukaemia survivor meets her stem cell donor - BBC News

A woman from Twickenham who survived leukaemia meets the man who donated the stem cells which saved her life.  
bbc.co.uk
over 4 years ago
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Red Blood Cell Processing Method and In-hospital Mortality

Fresh whole blood filtered units are associated with increased in-hospital mortality compared with mid-age red cell filtered units, researchers from Canada have observed.  
medscape.com
over 4 years ago
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Combined Surgical Approach Effective for Severe Sleep Apnea

For adults with severe obstructive sleep apnea (OSA), combined coblation endoscopic lingual lightening (CELL) and relocation pharyngoplasty yields better outcomes than relocation pharyngoplasty alone.  
medscape.com
over 4 years ago
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Uterine Stem Cell Deficiency Tied to Recurrent Miscarriage

A lack of stem cells and the aging of cells in the uterine lining could explain why some women experience recurrent miscarriages. A prepregnancy test could determine women at risk, researchers said.  
medscape.com
over 4 years ago
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Role of Immune Cells in Hypertension and Renal Injury

Find out more about the immune mechanisms involved in the development of salt-sensitive hypertension and renal disease.  
medscape.com
over 4 years ago
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'Intriguing': Do Blood Cells Herald Breast Cancer Return?

A high neutrophil-to-lymphocyte ratio (NLR) may predict worse prognosis in patients with early breast cancer, in this Italian study.  
medscape.com
over 4 years ago
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Crohn's, Colitis Congress Combines Original Research, Advice

Large, randomized trials on cell therapies, drug safety, the perioperative management of patients, and practical advice from experts from around the world will be highlighted at the congress.  
medscape.com
over 4 years ago
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Stem cells 'link' to repeat miscarriages, say scientists - BBC News

A lack of stem cells in the womb lining is causing thousands of women to suffer repeat miscarriages, say researchers in Warwick.  
bbc.co.uk
over 4 years ago