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Immuno-oncology Driving More Precise Cancer Treatment

A predicted shift in combination treatments, in which new immunotherapies treat the host, not the tumor cells, will mean that oncologists could become immunologists and virologists.  
medscape.com
over 4 years ago
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Zika caught 'killing' brain cells - BBC News

Zika virus kills the type of tissue found in the developing brain, researchers have shown.  
bbc.co.uk
over 4 years ago
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New FDA Guidelines Aim to Prevent Zika Transmission Via Tissue, Cell Donation

The U.S. Food and Drug Administration on Tuesday issued new recommendations aimed at reducing the risk of Zika virus transmission through donated human tissues and cells used in surgical or reproductive procedures, such as umbilical cord blood, corneas and heart valves.  
medscape.com
over 4 years ago
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Study on potato consumption will increase confusion regarding food and the risk of gestational diabetes

Using data from the Nurses’ Health Study II, Bao and colleagues found a higher prevalence of gestational diabetes mellitus (GDM) with increasing potato consumption.1 The authors stated that the high glycaemic index of potatoes, which causes a sharp postprandial rise in blood glucose concentrations and a risk of associated pancreatic β cells exhaustion, could explain this association.  
feeds.bmj.com
over 4 years ago
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Stem Cell Transplant in Multiple Sclerosis: Next Steps

Hematopoietic stem cell transplant looks promising in relapsing MS, while more biologically cell-based approaches may be needed for progressive forms. Two important studies are in development.  
medscape.com
over 4 years ago
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“Vaginal seeding” of infants born by caesarean section

The microbiota is the community of microbes that colonises our bodies, outnumbering our own cells 10 to 1.1 This complex microbial community varies from one part of the body to another, and from one person to another. Characteristic differences in the microbiota are associated with various diseases.2 As a result interest has surged in the potential for manipulating the microbiota to promote health and treat disease.2  
feeds.bmj.com
over 4 years ago
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“Vaginal seeding” of infants born by caesarean section

The microbiota is the community of microbes that colonises our bodies, outnumbering our own cells 10 to 1.1 This complex microbial community varies from one part of the body to another, and from one person to another. Characteristic differences in the microbiota are associated with various diseases.2 As a result interest has surged in the potential for manipulating the microbiota to promote health and treat disease.2  
feeds.bmj.com
over 4 years ago
Preview
0
0

“Vaginal seeding” of infants born by caesarean section

The microbiota is the community of microbes that colonises our bodies, outnumbering our own cells 10 to 1.1 This complex microbial community varies from one part of the body to another, and from one person to another. Characteristic differences in the microbiota are associated with various diseases.2 As a result interest has surged in the potential for manipulating the microbiota to promote health and treat disease.2  
feeds.bmj.com
over 4 years ago
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What are myeloproliferative disorders?

Learn about 4 different cancers that involve the bone marrow and produce a large number of cells in the blood stream. By Raja Narayan. Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT related content. These videos do not provide medical advice and are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any Khan Academy video.  
khanacademy.org
over 4 years ago
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'Releasing the Dogs’ in the Body’s War on Cancer

Drs Lou Weiner and Chris Heery vividly describe strategies that prompt the immune system to attack and kill cancer cells, and offer a view from the trenches of cancer immunotherapy.  
medscape.com
over 4 years ago
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Match4Zara: Social media boosts cell donor search - BBC News

The family of a 13-year-old girl urgently seeking a blood stem cell donor are "amazed" by the social media response they have had.  
bbc.co.uk
over 4 years ago
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Visualizing How Cancer Cells Coalesce to Form 'Tumors'

In real time, scientists at the University of Iowa have used computerized 3D images to show how cancer cells recruit surrounding cells into a growing 'tumor mass.'  
medscape.com
over 4 years ago
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Risk of invasive cervical cancer after atypical glandular cells in cervical screening: nationwide cohort study

Objectives To investigate the risks of invasive cervical cancer after detection of atypical glandular cells (AGC) during cervical screening.  
feeds.bmj.com
over 4 years ago
Www.bmj
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Atypical glandular cells on cervical cytology

“How worried should I be?” is what women often ask when told that their screening cervical cytology result is abnormal. Unfortunately, when the result indicates atypical glandular cells (AGC), it is difficult to answer this question with certainty. The study by Wang and colleagues,1 assessing the short and long term risk of cervical cancer after detection of AGC from cervical smear tests in Sweden, provides useful information. The team examined the risk of cervical cancer up to 15 years after a first finding of AGC in a cohort of over three million women. The large sample makes it possible to provide precise estimates of risk following this rare diagnostic category. Glandular pathologies are difficult to diagnose and may be under-ascertained in the short term, making studies with longitudinal assessment and minimal losses to follow-up essential. The fact …  
feeds.bmj.com
over 4 years ago
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Bacteria 'see' like tiny eyeballs - BBC News

Biologists discover how bacteria sense light and move towards it: the entire single-cell organism focuses light like a tiny eyeball.  
bbc.co.uk
over 4 years ago
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Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about factors that induce this reprogramming. Here, we demonstrate induction of pluripotent stem cells from mouse embryonic or adult fibroblasts by introducing four factors, Oct3/4, Sox2, c-Myc, and Klf4, under ES cell culture conditions. Unexpectedly, Nanog was dispensable. These cells, which we designated iPS (induced pluripotent stem) cells, exhibit the morphology and growth properties of ES cells and express ES cell marker genes. Subcutaneous transplantation of iPS cells into nude mice resulted in tumors containing a variety of tissues from all three germ layers. Following injection into blastocysts, iPS cells contributed to mouse embryonic development. These data demonstrate that pluripotent stem cells can be directly generated from fibroblast cultures by the addition of only a few defined factors.  
ac.els-cdn.com
over 4 years ago
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Side Effects With Sorafenib More Pronounced in Thyroid Cancer

The incidence of side effects from the oral multikinase inhibitor sorafenib appears to be considerably higher among patients with differentiated thyroid cancer than those with renal cell or hepatocellular carcinoma.  
medscape.com
over 4 years ago
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HIV Life Cycle

How HIV infects a cell and replicates itself using reverse transcriptase.  
youtube.com
over 4 years ago
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Scientists Watch as Healthy Cells Turn Into Melanoma

Harvard researchers have engineered zebrafish to track melanoma as it begins with its initiation from neural crest progenitor-like cells. Can these observations help stop cancer before it even begins?  
medscape.com
over 4 years ago
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Osimertinib Okayed in Europe for Lung Cancer Subgroup

The drug was fast tracked because it addresses an unmet need in advanced non-small-cell lung cancer.  
medscape.com
over 4 years ago