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CoronaryArteryDisease

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DNA shows why being short can be bad for your heart

When Randy Newman sang his tongue-in-cheek tune about short people, he called attention to their “little hands, little eyes” and their “little baby legs.” Nowhere does his 1978 hit mention that short people also have an increased risk of coronary artery disease. But scientists have established...  
latimes.com
over 5 years ago
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Short people have increased heart disease risk, study finds

A large study in the New England Journal of Medicine adds to the growing evidence linking shorter stature to a greater risk of Coronary Artery Disease. Cardiologist Dr. Tara Narula joins "CBS This Morning" to discuss the concerns.  
cbsnews.com
over 5 years ago
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Common antidepressant increased coronary atherosclerosis in animal model

A commonly prescribed antidepressant caused up to a six-fold increase in atherosclerosis plaque in the coronary arteries of non-human primates, according to a study. Coronary artery atherosclerosis is the primary cause of heart attacks.  
sciencedaily.com
over 5 years ago
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Common antidepressant increased coronary atherosclerosis in animal model

A commonly prescribed antidepressant caused up to a six-fold increase in atherosclerosis plaque in the coronary arteries of non-human primates, according to a study by researchers at Wake Forest Baptist Medical Center. Coronary artery atherosclerosis is the primary cause of heart attacks.  
eurekalert.org
over 5 years ago
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Surgery improves survival in diabetic patients with heart disease

Among diabetic patients with severe heart disease, coronary artery bypass grafting (CABG) surgery is better than stenting (percutaneous coronary intervention; PCI) at improving long-term survival and reducing the risk of adverse complications, a study confirms.  
sciencedaily.com
over 5 years ago
Www.bmj
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Assessment of chest pain in a low risk patient: is the exercise tolerance test obsolete?

The coronary artery calcium score has high sensitivity for detecting coronary stenosis—so a negative result makes significant coronary stenosis unlikely—but low specificity, and 60% of those without coronary artery disease will also have a positive result  
feeds.bmj.com
over 5 years ago
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Assessment of chest pain in a low risk patient: is the exercise tolerance test obsolete?

The coronary artery calcium score has high sensitivity for detecting coronary stenosis—so a negative result makes significant coronary stenosis unlikely—but low specificity, and 60% of those without coronary artery disease will also have a positive result  
feeds.bmj.com
over 5 years ago
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Extra calcium to prevent high blood pressure | Cochrane

Hypertension is a serious health problem that increases the risk of heart and kidney diseases. Several studies have shown that increasing calcium intake lowers blood pressure even in individuals within a normal blood pressure range. Increasing calcium intake also has benefits for pregnancy outcomes, effects which are thought to be mediated also by blood pressure reduction. High blood pressure has been identified as a major risk factor for mortality and even small reductions in blood pressure can decrease the occurrence of coronary artery disease, stroke and death.  
cochrane.org
about 5 years ago
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Michael Oliver obituary

One of the most eminent cardiovascular researchers of his generation, he demonstrated the relationship between cholesterol and coronary artery disease  
theguardian.com
about 5 years ago
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Prophylactic lidocaine for myocardial infarction | Cochrane

Background Coronary artery disease is a major public health problem that affects both developed and developing countries. Acute coronary syndromes include unstable angina and myocardial infarction with or without ST-segment elevation (electrocardiogram sector is higher than baseline). Ventricular arrhythmia after myocardial infarction is associated with high risk of mortality. The evidence is out of date, and considerable uncertainty remains about the effects of prophylactic lidocaine use on all-cause mortality, in particular, in patients with suspected myocardial infarction.  
cochrane.org
about 5 years ago
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Antiplatelet Treatment Considerations for High-Risk Cardiovascular Patients: A Focus on Aspirin CME

This activity has been developed to meet the educational needs of physicians involved in the care of patients with coronary artery disease.  
medscape.org
almost 5 years ago
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Factors Associated With No Apparent CAD in T2D

Type 2 diabetics are at a greater risk for developing coronary artery disease, but some patients remain free of the disease. Which factors may account for this?  
medscape.com
almost 5 years ago
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Can Early Fruit, Vegetable Consumption Prevent Later CV Risk? CME/CE

: Eating more fruits and vegetables early in adulthood yields lower rates of coronary atherosclerosis decades later, a new longitudinal cohort study finds.  
medscape.org
almost 5 years ago
Www.bmj
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Cardiovascular risks associated with clarithromycin

Concerns about the cardiovascular risks of macrolide antibiotics surfaced in the 1980s, with case reports and clinical studies describing arrhythmias and QT prolongation with erythromycin.1 2 These concerns subsequently extended to azithromycin3 and clarithromycin,4 two other members of the macrolide class. For example, a large cohort study using Danish healthcare data showed, on average, a 76% higher risk of cardiovascular mortality with current use of clarithromycin compared with penicillin V among middle aged patients, translating into an adjusted absolute risk difference of 37 cardiac deaths per million courses.4 The authors acknowledged concerns about confounding by indication and residual confounding. However, in a randomised controlled trial without such problems, a two week course of clarithromycin increased the risk of cardiovascular death for three years, compared with placebo, among patients with stable coronary artery disease.5  
feeds.bmj.com
over 4 years ago
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Cardiovascular risks associated with clarithromycin

Concerns about the cardiovascular risks of macrolide antibiotics surfaced in the 1980s, with case reports and clinical studies describing arrhythmias and QT prolongation with erythromycin.1 2 These concerns subsequently extended to azithromycin3 and clarithromycin,4 two other members of the macrolide class. For example, a large cohort study using Danish healthcare data showed, on average, a 76% higher risk of cardiovascular mortality with current use of clarithromycin compared with penicillin V among middle aged patients, translating into an adjusted absolute risk difference of 37 cardiac deaths per million courses.4 The authors acknowledged concerns about confounding by indication and residual confounding. However, in a randomised controlled trial without such problems, a two week course of clarithromycin increased the risk of cardiovascular death for three years, compared with placebo, among patients with stable coronary artery disease.5  
feeds.bmj.com
over 4 years ago
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Emergency Medicine Literature of Note: CTCA in the ED, Getting Less Sexy By The Day

Hello, there, Thanks for fishing this. I can't comment on the paper but what I read in the abstract is intersting. A somewhat physician influenced outcome (patients identified with significant coronary artery disease requiring revascularisation within 30 days. The the best fullproof endpoint , ikely the "least worse" for the patient number in the study. A test, CTCA, that does not improve this outcome. But that seems to stop dotors from further investigating patients: "The CCTA group ... less outpatient testing after the index ED visit (10 [4%] vs. 26 [10%], p < 0.01).".I'm still to understand how one can explain that adding CTCA , within a 6hours stay in the ED may lead to this finding: "The CCTA group had lower direct medical costs (€337 vs. €511, p < 0.01)".Oh and by the way, what do our West of the pond colleagues think of the efficiency of a system , in the Netherlands where the cost of 6 hours in the ED with troponins, nurses, docs, documentation, and a high tech imaging study results in MEDICAL COSTS OF €337 vs. €511 without the CTCA. (I hope I didnt miss something). This last paragraph is in tongue in cheek - leg-pulling mode of course.  
emlitofnote.com
over 4 years ago
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Subtle ECG Findings in ACS: Part I Left Main Coronary Artery Disease - emdocs

we will look at ECG findings associated with left main coronary artery disease and explore the significance of ST-segment elevation in the “forgotten lead”.  
emdocs.net
over 4 years ago
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Late Failing Heart Allografts

Learn more about the role of antibody-mediated rejection and coronary arteriosclerosis in late failing heart allografts.  
medscape.com
over 4 years ago
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Single- vs. Multi-Staged PCI in Multivessel NSTEMI Patients

Which is the preferable strategy in patients with NSTEMI and multivessel coronary artery disease: single-staged or multi-staged PCI?  
medscape.com
over 4 years ago
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Subtle ECG Findings in ACS: Part I Left Main Coronary Artery Disease - emdocs

we will look at ECG findings associated with left main coronary artery disease and explore the significance of ST-segment elevation in the “forgotten lead”.  
emdocs.wpengine.com
over 4 years ago