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Assessment and management of behavioral and psychological symptoms of dementia

Behavioral and psychological symptoms of dementia include agitation, depression, apathy, repetitive questioning, psychosis, aggression, sleep problems, wandering, and a variety of inappropriate behaviors. One or more of these symptoms will affect nearly all people with dementia over the course of their illness. These symptoms are among the most complex, stressful, and costly aspects of care, and they lead to a myriad of poor patient health outcomes, healthcare problems, and income loss for family care givers. The causes include neurobiologically related disease factors; unmet needs; care giver factors; environmental triggers; and interactions of individual, care giver, and environmental factors. The complexity of these symptoms means that there is no “one size fits all solution,” and approaches tailored to the patient and the care giver are needed. Non-pharmacologic approaches should be used first line, although several exceptions are discussed. Non-pharmacologic approaches with the strongest evidence base involve family care giver interventions. Regarding pharmacologic treatments, antipsychotics have the strongest evidence base, although the risk to benefit ratio is a concern. An approach to integrating non-pharmacologic and pharmacologic treatments is described. Finally, the paradigm shift needed to fully institute tailored treatments for people and families dealing with these symptoms in the community is discussed.  
feeds.bmj.com
over 5 years ago
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Dementia team award

Dementia care today has a higher profile, helped by the government’s dementia strategy and driven by the enthusiasm of clinicians to seize the moment and make a difference. Nigel Hawkes presents the shortlisted teams  
feeds.bmj.com
over 5 years ago
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Most common cause of death in England and Wales in 2013 was heart disease in men and dementia in women

The leading cause of death among men in England and Wales in 2013 was ischaemic heart disease, accounting for 15.4% of deaths, while among women it was dementia and Alzheimer’s disease, which caused 12.2% of deaths, show the latest statistics.1 Dementia and Alzheimer’s disease overtook heart disease as the leading cause of death among women in 2012.  
feeds.bmj.com
over 5 years ago
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New study will test if anti-amyloid antibody can prevent development of Alzheimer's disease

Researchers at the University of Pittsburgh School of Medicine will be part of a multicenter trial that will test for the first time whether a drug that treats brain plaques can prevent later...  
medicalnewstoday.com
over 5 years ago
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Genetics overlap found between Alzheimer's disease and cardiovascular risk factors

An international team of scientists, led by researchers at University of California, San Diego School of Medicine, have found genetic overlap between Alzheimer's disease (AD) and two...  
medicalnewstoday.com
over 5 years ago
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New method helps establish south Asian perceptions of dementia

Dementia care for south Asian people could be improved after researchers from The University of Manchester adapted a commonly used tool for judging perceptions of the disease.  
medicalnewstoday.com
over 5 years ago
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Depression and diabetes combined may create even higher risk of cognitive decline

Depression and diabetes each raised dementia risk on their own, but risk rose even more for people with both, in a large study of Alzheimer's disease and vascular dementia.  
medicalnewstoday.com
over 5 years ago
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Being underweight increases dementia risk, while obesity reduces it, study finds

While past research suggests obesity increases dementia risk, a new study finds this may not be the case. Instead, being underweight may increase risk of the condition.  
medicalnewstoday.com
over 5 years ago
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Drug discovery gives hope to halting progression of Alzheimer's disease

A drug used to treat stroke victims could help stop the progression of Alzheimer's disease according to new research.  
medicalnewstoday.com
over 5 years ago
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NTU scientists discover new treatment for dementia

New brain cells can be formed through deep brain stimulation, improving memory retentionPushing new frontiers in dementia research, Nanyang Technological University...  
medicalnewstoday.com
over 5 years ago
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Beta secretase inhibitors to treat Alzheimer's disease

A note of caution from a new study in Biological PsychiatryWith each new amyloid-targeting treatment for Alzheimer's disease that has been developed, there has...  
medicalnewstoday.com
over 5 years ago
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Can caffeine be used to treat or prevent Alzheimer's disease?

The proposed link between caffeine and reductions in the beta amyloid plaque accumulation characteristic of Alzheimer's disease (AD) suggest a possible role for caffeine in AD treatment.  
medicalnewstoday.com
over 5 years ago
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Alzheimer's Research UK report reveals dementia hits women hardest

The impact of dementia is being felt disproportionately by women, according to a new report published by Alzheimer's Research UK, the UK's leading dementia research charity.  
medicalnewstoday.com
over 5 years ago
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Infectious prion protein discovered in urine of patients with variant Creutzfeldt-Jakob disease

The misfolded and infectious prion protein that is a marker for variant Creutzfeldt-Jakob disease - linked to the consumption of infected cattle meat - has been detected in the urine of patients...  
medicalnewstoday.com
over 5 years ago
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Study examines blood test to screen for fatal variant creutzfeldt-jakob disease

A blood test accurately screened for infection with the agent responsible for variant Creutzfeldt-Jakob disease (vCJD), a fatal neurological disease.  
medicalnewstoday.com
over 5 years ago
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Experts criticise 'inaccurate' view that B Vitamins have no role in Alzheimer's disease prevention

Patients in the very early stages of dementia could miss out on a potentially effective treatment after misleading research was published last year, say medical experts.  
medicalnewstoday.com
over 5 years ago
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Malnutrition in U.S. - greatest cost linked to seniors, depression, COPD, coronary artery disease and dementia

Even in food-abundant industrialized countries like the U.S., an alarming number of people, particularly seniors, are in a state of diseased-associated malnutrition1.  
medicalnewstoday.com
over 5 years ago
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Drug restores brain function and memory in early Alzheimer's disease

A novel therapeutic approach for an existing drug reverses a condition in elderly patients who are at high risk for dementia due to Alzheimer's disease, researchers at Johns Hopkins University...  
medicalnewstoday.com
over 5 years ago
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Study finds major vascular anomalies in the brains of people with Huntington's disease

An international study led by researchers from Université Laval and CHU de Québec-Université Laval has identified significant vascular changes in the brains of people with Huntington's...  
medicalnewstoday.com
over 5 years ago
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New test measures deadly protein in Huntington's disease patients' spinal fluid

A new test has been able to measure for the first time the build-up of a harmful mutant protein in the nervous system of patients during the progression of Huntington's...  
medicalnewstoday.com
over 5 years ago