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Acne Vulgaris

A disorder of the Pilosebaceous Follicles Aetiology  
almostadoctor.com - free medical student revision notes
over 5 years ago
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Bullous Pemphigoid

Aetiology Elderly (>65yrs) Vaccinations (in children with  condition affecting face, palms and soles)  NSAIDs, furosemide, antibiotics UV radiation / x-rays   Pathophysiology  
almostadoctor.com - free medical student revision notes
over 5 years ago
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Bullous Pemphigus

Bullous PemphiguS (superficial) Aetiology  Middle aged (40-60yrs)  High prevalence in Jewish regions  Lifelong condition   Pathophysiology  
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over 5 years ago
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Dermatitis Herpetiformis

 
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over 5 years ago
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Eczema (Dermatitis)

Eczema (aka Dermatitis) presents as a poorly demarcated, itchy rash. There are several causes. By far the most common is atopic eczema, but irritants and venous stasis can also cause the condition.   Atopic Eczema This results from an IgE-mediated, T-cell auto-immune response.   Epidemiology and Aetiology  
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over 5 years ago
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Psoriasis

Pathology Keratinocyte hyperproliferation: differentiation, or ‘skin cell going from basal layer to horny layer’, reduced from 4 weeks to 4 days [approximately!] Histopathological features: Parakeratosis: retained nuclei Acanthosis: thick epidermis Absent granular layer Lengthened rete ridges Thin dermal papillae  
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over 5 years ago
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Scabies

Scabies aka “The Itch” Caused by the arachnid (mite) sarcotopes scabei.   Aetiology Pets – particularly dogs Other family members affected – highly contagious within families. Sexually transmitted   Presentation  
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over 5 years ago
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Skin Cancer

Skin cancer is the most common malignancy – and the incidence is increasing rapidly In the last 10 years, the incidence in the UK has doubled Responsible for 2% of cancer deaths each year 80% of these are melanoma   General Risk Factors Age Sun bed use Fair skin Hx of sunburn Hx of living overseas FH Occupations – outdoors – e.g. bricklayer  
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over 5 years ago
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Breast Cancer

Remember, although rare, men can also get breast cancer. Less than 1% of breast cancers occur in men. Benign breast masses are 15x more common than breast cancer   Epidemiology In the UK, a woman has a 1/9 chance of developing breast cancer It is the most common cause of death in women aged 35-55  
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over 5 years ago
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Giant Cell Arteritis

Giant Cell Arteritis (GCA) aka Temporal Arteritis  
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over 5 years ago
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Neurofibromatosis

There are two types of neurofibromatosis, both inherited in an autosomal dominant manner, although some cases arise from spontaneous mutation. It results in benign tumours of the nervous system and bony and dermatological deformities.   Type I Neurofibromatosis – NF1 – aka von Recklinghausen’s disease  
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over 5 years ago
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Fifth Disease

Fifth Disease - so called as it was the fifth of the six common childhood skin rashes when it was first classified back in the 18th and 19th centuries. Formally known as Erythema Infectiosum and also colloquially called slapped cheek syndrome. Aietiology and Epidemiology  Caused by infection with Parvovirus B19 (aka erythrovirus)    
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over 5 years ago
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Kawasaki Disease

 
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over 5 years ago
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Rashes of Childhood

Type of Rash Appearance  
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over 5 years ago
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Leishmaniasis

 
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Sepsis and SIRS

Definitions. Before discussing SIRS along with the various sepsis syndromes, it is important to understand some basic definitions. Infection: This is the inflammatory response initiated by the presence of a micro-organisms in normally sterile tissue. Bacteraemia: The presence of live bacteria in the blood stream. This can occur in a healthy individual and present with no symptoms. Common causes include surgery, dental procedures and even tooth brushing.  
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over 5 years ago
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Breast cancer drug turned down for NHS use due to high cost

Decision on Herceptin-style drug which costs £90,000 but can prolong lives by nearly six months heavily criticised  
the Guardian
over 5 years ago
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Human skin grown in lab 'can replace animal testing' - BBC News

Skin grown in the laboratory could replace animals in drug and cosmetics testing, according to UK scientists.  
BBC News
over 5 years ago
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Breast cancer drug price reduction urged - BBC News

Campaigners urge pharmaceutical giant Roche to lower the cost of a pioneering breast cancer drug as the NHS prepares to rejects its use on price grounds.  
BBC News
over 5 years ago
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Breast cancer drug Kadcyla price reduction urged - BBC News

The medicines watchdog for England and Wales says it is disappointed that the drug company Roche will not reduce the price of a new breast cancer drug for the NHS.  
BBC News
over 5 years ago