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Rash decisions

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A rash oversight

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over 7 years ago
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Missed breast cancer

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over 7 years ago
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Psoriatic Arthritis

Psoriasis is an autoimmune condition which affects the skin and joints. It is sometimes referred to as one of the spondyloarthritides (inflammatory arthritis that is seronegative for rheumatoid factor (and/or does not fit the criteria for diagnosis as RA)).   Definitions  
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Ehlers-Danlos Syndrome (EDS)

Ehlers-Danlos syndrome is an inherited connective tissue disorder caused by defective collagen synthesis. Symptoms vary widely between individuals. Some may be hardly effected, whilst other live severely restricted lives.   Epidemiology and Aetiology    
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Systemic Sclerosis

Systemic sclerosis is an autoimmune connective tissue disorder. Other similar diseases include SLE, RA, Sjogren’s syndrome and mixed connective tissue disease. There is a lot of overlap in the symptoms of these diseases. Many will require immunosuppressive therapy.  
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over 7 years ago
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Acne Vulgaris

A disorder of the Pilosebaceous Follicles Aetiology  
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over 7 years ago
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Bullous Pemphigoid

Aetiology Elderly (>65yrs) Vaccinations (in children with  condition affecting face, palms and soles)  NSAIDs, furosemide, antibiotics UV radiation / x-rays   Pathophysiology  
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Bullous Pemphigus

Bullous PemphiguS (superficial) Aetiology  Middle aged (40-60yrs)  High prevalence in Jewish regions  Lifelong condition   Pathophysiology  
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Dermatitis Herpetiformis

 
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Eczema (Dermatitis)

Eczema (aka Dermatitis) presents as a poorly demarcated, itchy rash. There are several causes. By far the most common is atopic eczema, but irritants and venous stasis can also cause the condition.   Atopic Eczema This results from an IgE-mediated, T-cell auto-immune response.   Epidemiology and Aetiology  
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Psoriasis

Pathology Keratinocyte hyperproliferation: differentiation, or ‘skin cell going from basal layer to horny layer’, reduced from 4 weeks to 4 days [approximately!] Histopathological features: Parakeratosis: retained nuclei Acanthosis: thick epidermis Absent granular layer Lengthened rete ridges Thin dermal papillae  
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over 7 years ago
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Scabies

Scabies aka “The Itch” Caused by the arachnid (mite) sarcotopes scabei.   Aetiology Pets – particularly dogs Other family members affected – highly contagious within families. Sexually transmitted   Presentation  
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Skin Cancer

Skin cancer is the most common malignancy – and the incidence is increasing rapidly In the last 10 years, the incidence in the UK has doubled Responsible for 2% of cancer deaths each year 80% of these are melanoma   General Risk Factors Age Sun bed use Fair skin Hx of sunburn Hx of living overseas FH Occupations – outdoors – e.g. bricklayer  
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over 7 years ago
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Breast Cancer

Remember, although rare, men can also get breast cancer. Less than 1% of breast cancers occur in men. Benign breast masses are 15x more common than breast cancer   Epidemiology In the UK, a woman has a 1/9 chance of developing breast cancer It is the most common cause of death in women aged 35-55  
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over 7 years ago
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Giant Cell Arteritis

Giant Cell Arteritis (GCA) aka Temporal Arteritis  
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over 7 years ago
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Neurofibromatosis

There are two types of neurofibromatosis, both inherited in an autosomal dominant manner, although some cases arise from spontaneous mutation. It results in benign tumours of the nervous system and bony and dermatological deformities.   Type I Neurofibromatosis – NF1 – aka von Recklinghausen’s disease  
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over 7 years ago
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Fifth Disease

Fifth Disease - so called as it was the fifth of the six common childhood skin rashes when it was first classified back in the 18th and 19th centuries. Formally known as Erythema Infectiosum and also colloquially called slapped cheek syndrome. Aietiology and Epidemiology  Caused by infection with Parvovirus B19 (aka erythrovirus)    
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Kawasaki Disease

 
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Rashes of Childhood

Type of Rash Appearance  
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