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The impact of biological interventions for ulcerative colitis on health-related quality of life | Cochrane

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by abdominal pain, urgent bowel movements and bloody diarrhea. Treatment of UC focuses on induction of remission (treatment of symptoms of active disease) and prevention of clinical relapse (resumption of symptoms of active disease) in patients in remission (known as maintenance therapy). UC has a major impact on patients' health related quality of life (HRQL). HRQL refers to a person's physical functioning, social and emotional well-being, ability to work and freedom from disease symptoms. HRQL is significantly lower in patients with UC compared to the general population. Randomized controlled trials (RCTs) evaluating medical interventions for UC have traditionally used clinical disease activity indices which focus on subjective symptoms to define primary outcomes such as clinical remission or improvement. This focus on disease symptoms results in a failure to assess other important indicators of successful treatment such as HRQL.  
cochrane.org
over 6 years ago
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Inflammatory bowel disease

Diarrhoea of >6 weeks’ duration, especially with weight loss and where cancer is not suspected, warrants testing (such as full blood count, C reactive protein or erythrocyte sedimentation rate, coeliac antibodies, and thyroid function)  
feeds.bmj.com
over 6 years ago
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Inflammatory bowel disease

Diarrhoea of >6 weeks’ duration, especially with weight loss and where cancer is not suspected, warrants testing (such as full blood count, C reactive protein or erythrocyte sedimentation rate, coeliac antibodies, and thyroid function)  
feeds.bmj.com
over 6 years ago
Www.bmj
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Study finds “know-do” gap in treatment of pneumonia and diarrhoea in children in rural areas

Many rural paediatric healthcare practitioners in India are not correctly diagnosing and managing pneumonia and diarrhoea, two of the leading causes of children’s deaths, a study has shown.  
feeds.bmj.com
over 6 years ago
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Evidence many young children with autism show gut symptoms

Gastrointestinal symptoms of constipation, diarrhea and food allergy/intolerance up to 3 years of age were more likely to be seen by mothers of infants with autism in study.  
medicalnewstoday.com
over 6 years ago
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Salix's TARGET 3 study examines the safety and efficacy of repeat treatment with Rifaximin for IBS with diarrhea

Salix Pharmaceuticals, Ltd. has announced that Dr. Anthony Lembo of Beth Israel Deaconess Medical Center will present the results of TARGET 3 in a late-breaking podium presentation at the...  
medicalnewstoday.com
over 6 years ago
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Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea

Stream Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea by BMJ talk medicine from desktop or your mobile device  
feeds.bmj.com
over 6 years ago
Sinaiem dark
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lump-in-my-throat

A 19-year-old-male with no known past medical history, presents in progressive respiratory distress shortly after undergoing a tooth extraction about 6 hours prior to presentation. Symptoms began initially as “a lump in his throat” and difficulty swallowing, but eventually progressed to mild dyspnea after 1-2 hours. Denies FB or allergies. On arrival he appears anxious and is breathing at 18 breaths per minute with an O2 saturation of 100%. There is no stridor at presentation. There is no intra-oral, facial, or obvious neck swelling. There is no skin involvement or abdominal pain, nausea, vomiting or diarrhea. You suspect allergic reaction and give IM epi, IV steroids, benadryl and pepcid. ENT is consulted for scope.  
sinaiem.org
over 6 years ago
Sinaiem dark
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slow-and-steady

75 y/o M with a past medical history of atrial fibrillation presents to the ED not feeling well for several days. He has some diarrhea but has continued to take his medications. He is mildly hypotensive. While IV access is established, you are shown his ECG….  
sinaiem.org
over 6 years ago
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SGEM#117: Diarrhea – Hard to Spell, Easy to Smell and Easy to Cause with IV Antibiotics

Guest Skeptics: Meghan Groth (@EMPharmGirl). Meghan is the emergency medicine pharmacy specialist at the University of Vermont Medical Center in Burlington, Vermont and an adjunct professor of pharmacy at the Albany College of Pharmacy and Health Sciences.  
thesgem.com
over 6 years ago