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361

A Medical Intern Writes to His Future Self

Dear future Pranay, By the time you read this, time will have passed with the same explosive inevitability that C diff diarrhea passes from unfortunate ...  
huffingtonpost.com
over 4 years ago
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The impact of biological interventions for ulcerative colitis on health-related quality of life | Cochrane

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by abdominal pain, urgent bowel movements and bloody diarrhea. Treatment of UC focuses on induction of remission (treatment of symptoms of active disease) and prevention of clinical relapse (resumption of symptoms of active disease) in patients in remission (known as maintenance therapy). UC has a major impact on patients' health related quality of life (HRQL). HRQL refers to a person's physical functioning, social and emotional well-being, ability to work and freedom from disease symptoms. HRQL is significantly lower in patients with UC compared to the general population. Randomized controlled trials (RCTs) evaluating medical interventions for UC have traditionally used clinical disease activity indices which focus on subjective symptoms to define primary outcomes such as clinical remission or improvement. This focus on disease symptoms results in a failure to assess other important indicators of successful treatment such as HRQL.  
cochrane.org
over 4 years ago
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Inflammatory bowel disease

Diarrhoea of >6 weeks’ duration, especially with weight loss and where cancer is not suspected, warrants testing (such as full blood count, C reactive protein or erythrocyte sedimentation rate, coeliac antibodies, and thyroid function)  
feeds.bmj.com
over 4 years ago
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71

Inflammatory bowel disease

Diarrhoea of >6 weeks’ duration, especially with weight loss and where cancer is not suspected, warrants testing (such as full blood count, C reactive protein or erythrocyte sedimentation rate, coeliac antibodies, and thyroid function)  
feeds.bmj.com
over 4 years ago
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Inflammatory bowel disease

Diarrhoea of >6 weeks’ duration, especially with weight loss and where cancer is not suspected, warrants testing (such as full blood count, C reactive protein or erythrocyte sedimentation rate, coeliac antibodies, and thyroid function)  
feeds.bmj.com
over 4 years ago
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Dr. Smith's ECG Blog: Extreme Bradycardia after Diarrhea and Dehydration. Best ED treatment?

Instructive ECGs in Clinical Context ----Archives, Popular Posts, and an Index of all ECGs are down the right-hand side.  
hqmeded-ecg.blogspot.com
over 4 years ago
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Lab case 74

A 14 year old female is brought in to your ED on a priority one by ambulance. She has had a one week history of vomiting and diarrhoea.  
emergucate.com
over 4 years ago
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Listeria warning over caramel apples - BBC News

Caramel-coated apples can be riddled with listeria - a bacterium that causes diarrhoea and vomiting and, rarely, meningitis - warn scientists.  
bbc.co.uk
over 4 years ago
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Interventions to improve water quality and prevent diarrhoea | Cochrane

This Cochrane Review summarizes trials evaluating different interventions to improve water quality and prevent diarrhoea. After searching for relevant trials up to 11 November 2014, we included 55 studies enrolling over 84,000 participants. Most included studies were conducted in low- or middle-income countries (LMICs) (50 studies), with unimproved water sources (30 studies), and unimproved or unclear sanitation (34 studies).  
cochrane.org
over 4 years ago
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Oral budesonide for treatment of people with active ulcerative colitis | Cochrane

Ulcerative colitis is a debilitating long-term (chronic), inflammatory bowel disease that affects the large bowel. When people with ulcerative colitis are experiencing symptoms which may include bleeding, diarrhoea and abdominal pain, the disease is said to be 'active'; periods when the symptoms stop are called 'remission'. A common initial treatment of ulcerative colitis is oral steroid therapy. Unfortunately, conventional steroids are usually absorbed into the body and cause significant unwanted side-effects. These may include but are not limited to weight gain, diabetes, growth retardation, acne, mood instability, and high blood pressure.  
cochrane.org
over 4 years ago
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Diarrhoea and vomiting caused by gastroenteritis in under 5s: diagnosis and management | Guidance and guidelines | NICE

This guideline applies to children younger than 5 years who present to a healthcare professional for advice in any setting. It covers diagnosis, assessment of dehydration, fluid management, nutritional management and the role of antibiotics and other therapies. It provides recommendations on the advice to be given to parents and carers, and also considers when care should be escalated - from home management through to hospital admission.  
nice.org.uk
over 4 years ago
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Acute diarrhoea in adults: racecadotril | relevance-to-nice-guidance-programmes | Advice | NICE

Racecadotril was not considered appropriate for a NICE technology appraisal and is not currently planned into any other NICE work programme.  
nice.org.uk
over 4 years ago
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Acute diarrhoea in children: racecadotril as an adjunct to oral rehydration | relevance-to-nice-guidance-programmes | Advice | NICE

Racecadotril was not considered appropriate for a NICE technology appraisal and is not currently planned into any other NICE work programme.  
nice.org.uk
over 4 years ago
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Bile acid malabsorption: colesevelam | Key-points-from-the-evidence | Advice | NICE

The use of colesevelam for bile acid malabsorption is reported in 2 small case series (n=45 and n=5), which found that colesevelam improved diarrhoea and gastrointestinal symptoms in people with this condition. A randomised controlled trial (RCT) found no improvement in outcomes with colesevelam in 24 women with diarrhoea-predominant irritable bowel syndrome, 4 of whom had evidence of bile acid malabsorption. However, the study may have been underpowered to detect any differences between the groups. Colesevelam appears to be well tolerated; the most frequent adverse effects are flatulence and constipation.  
nice.org.uk
over 4 years ago
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Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease | Cochrane

What is Crohn's disease? Crohn's disease is a long-term chronic inflammatory bowel disease that can affect any part of the gastrointestinal tract from mouth to anus. Symptoms include abdominal pain, non-bloody diarrhea and weight loss. When people with Crohn's disease are experiencing symptoms of the disease it is said to be ‘active’; periods when the symptoms stop are called ‘remission’.  
cochrane.org
over 4 years ago
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Lab case 78

A 64 year old female with MELAS presents with a 3 day history of vomiting and diarrhoea. She had been on an overseas holiday recently.  
emergucate.com
over 4 years ago
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Lab Case 80

A 51 year old man is brought to your ED by his family. He has been slightly confused and also had diarrhoea and vomiting for the last three days.  
emergucate.com
over 4 years ago
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Therapy for treatment and prevention of pouchitis | Cochrane

Some patients with ulcerative colitis have their colon and rectum removed with construction of a pouch (made from a loop of small intestine) to serve in place of the rectum. This is known as ileal pouch-anal anastomosis (IPAA) surgery. Pouchitis is inflammation of the surgically constructed pouch. Symptoms of active pouchitis include diarrhea, increased stool frequency, abdominal cramping, fecal urgency, tenesmus (feeling of constantly needing to pass stools), and incontinence. Periods when symptoms stop are called 'remission'.  
cochrane.org
over 4 years ago
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Topical anaesthetic creams – Don't Forget the Bubbles

Six year old Angela comes into your department with a three day history of diarrhoea and vomiting. You determine that she needs cannulation both to assess her renal function and to begin treatment. You know that cannulating children can be a painful and traumatic experience and are keen to make it as stress-free as possible. The nurses ask you what you would like them to put on the child?  
dontforgetthebubbles.com
over 4 years ago
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Managing Side Effects of Immunotherapy: Diarrhea/Colitis

Dr Asim Amin, codirector of immunotherapy at Levine Cancer Institute, discusses the management of gastrointestinal side effects of immunotherapy.  
medscape.com
over 4 years ago