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Potential Mechanisms of Action of Rifaximin in IBS With Diarrhea

Could resetting microbial diversity via rifaximin lead to a decrease in bacterial fermentation and a reduction in the clinical symptoms of IBS?  
medscape.com
over 4 years ago
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Mixed Opioid Agent Adds to Growing List of Therapies for IBS-D

Studies suggest a new oral agent with mixed opioid effects may be a promising new option for irritable bowel syndrome with diarrhea; its approval adds to the growing list of options for the disorder.  
medscape.com
over 4 years ago
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Boring Question: Fecal Leukocytes. Eh? - CanadiEM

A 25-year-old woman presents with diarrhea x 3 weeks. She has reports 6-12 loose bowel movements per day with urgency and mucous which are associated with cramping abdominal pain and a 5lb weight loss. She has not noticed any blood in her stool and reports no other extra-intestinal manifestations of inflammatory bowel disease (IBD). She has not travelled recently and drinks out of a municipal water supply. None of her contacts have similar symptoms and she has had no changes to her diet. She has no family history of IBD but does have a family history of a variety of autoimmune conditions.  She is otherwise healthy and has had no recent contact with the health care system or use of antibiotics. Her vital signs are normal, she looks well and her abdominal exam is normal.  
canadiem.org
over 4 years ago
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Ivermectin versus benzimidazoles for treating Strongyloides stercoralis infection | Cochrane

Strongyloides stercoralis is a parasite that lives in the gut of infected people. The infection is not serious for most people, but it can be fatal in people with immune deficiency. People become infected when they come in contact with soil or water contaminated with infectious worms. The chronic infection usually causes skin rash, vomiting, diarrhoea, and constipation, and respiratory problems, such as asthma-like illness. This disease may be treated with ivermectin or albendazole or thiabendazole. We wanted to know if ivermectin was better or worse than the other alternative therapies.  
cochrane.org
over 4 years ago
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Toxicities of Anti-PD-1/PD-L1 Immune Checkpoint Antibodies

How do you manage diarrhea, fatigue, rash, and other adverse effects associated with anti-PD-1/anti-PD-L1 therapies?  
medscape.com
over 4 years ago
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8

New Targeted Therapies for Managing IBS-D in the GI Practice CME

This activity was developed for gastroenterologists with an interest in the management of irritable bowel syndrome with diarrhea (IBS-D). Other healthcare providers may also participate.  
medscape.org
about 4 years ago
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Shiga Toxin 1–Producing Shigella sonnei Infections, California, United States, 2014–2015: Abstract and Introduction

Abstract and Introduction: Shiga toxin 1-producing Shigella sonnei infection, often causing bloody diarrhea, has recently emerged in California and may spread in the United States.  
medscape.org
about 4 years ago
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Treatment Options for Microscopic Colitis

Microscopic colitis is diagnosed in a 64-year-old woman with a history of watery diarrhea. What is the most appropriate treatment option?  
medscape.com
about 4 years ago
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Travellers’ diarrhoea

Prophylactic antibiotic use is only recommended for patients vulnerable to severe sequelae after a short period of diarrhoea, such as those with ileostomies or immune suppression  
feeds.bmj.com
about 4 years ago
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Travellers’ diarrhoea

Prophylactic antibiotic use is only recommended for patients vulnerable to severe sequelae after a short period of diarrhoea, such as those with ileostomies or immune suppression  
feeds.bmj.com
about 4 years ago
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4

Travellers’ diarrhoea

Prophylactic antibiotic use is only recommended for patients vulnerable to severe sequelae after a short period of diarrhoea, such as those with ileostomies or immune suppression  
feeds.bmj.com
about 4 years ago
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2

Travellers’ diarrhoea

Prophylactic antibiotic use is only recommended for patients vulnerable to severe sequelae after a short period of diarrhoea, such as those with ileostomies or immune suppression  
feeds.bmj.com
about 4 years ago
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1

The Highs and Lows of Loperamide Abuse

How an over-the-counter medication for diarrhea has become a worrying and potentially lethal drug of abuse.  
medscape.com
about 4 years ago
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1

Adverse effects and tolerability of β blockers

Regarding side effects and tolerability of β blockers, Kotecha and colleagues state: “Although β blockers are often associated with side effects, data from randomised trials consistently show no true difference compared with placebo in dizziness, diarrhoea, increased blood sugar concentration, or depression …  
feeds.bmj.com
almost 4 years ago
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Adverse effects and tolerability of β blockers

Regarding side effects and tolerability of β blockers, Kotecha and colleagues state: “Although β blockers are often associated with side effects, data from randomised trials consistently show no true difference compared with placebo in dizziness, diarrhoea, increased blood sugar concentration, or depression …  
feeds.bmj.com
almost 4 years ago
Preview
0
2

Adverse effects and tolerability of β blockers

Regarding side effects and tolerability of β blockers, Kotecha and colleagues state: “Although β blockers are often associated with side effects, data from randomised trials consistently show no true difference compared with placebo in dizziness, diarrhoea, increased blood sugar concentration, or depression …  
feeds.bmj.com
almost 4 years ago