New to Meducation?
Sign up
Already signed up? Log In

Category

Preview
0
3

Humanity's global battle with mosquitoes - BBC News

All over the world we cannot escape the bite of the mosquito - and the diseases it carries.  
BBC News
over 6 years ago
Preview
4
90

ARDS - Acute Respiratory Distress Syndrome

ARDS – acute respiratory distress syndrome and ALI – acute lung injury, are essentially the same disease; ARDS is the more serious end of the spectrum, and for the purpose of this article, we will also refer to the disease as ARDS      
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
52

Sarcoidosis

Sarcoidosis is a multisystem granulamtous disorder of unknown aetiology. It most commonly affects the lungs (>90% of cases) and lymphatic system, but can affect any organ. Many cases are asymptomatic, although some patients can have very severe disease. Treatment may involve NSAIDs and less often, steroids, but often none is required as most cases resolve spontaneously.   Epidemiology and Aetiology  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
21

Bechet's Disease

Idiopathic, autoimmune disease, caused by inflammation of venules. Associated with HLA-B51, thought to be triggered by an environmental agent Symptoms include: Recurrent mouth and genital ulcers Uveitis Often accompanied by a symmetrical arthritis of the lower limbs! Non-erosive, and treated with steroids  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
2
57

Comparison and Summary of Types of Arthritis

Disease Location  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
60

Osteomalacia and Rickets

These are essentially the same disorder. In children, the disease is rickets but after fusion of the epiphyseal plates it is known as osteomalacia. The most common cause is vitamin D deficiency. The condition is characterised by normal bone formation with abnormal bone mineralisation, thus there is excess osteoid and cartilage, and insufficient bone.   Causes  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
26

Paget's Disease of the Bone

Along with osteoporosis, this is a common degenerative bone disease   Epidemiology and Aetiology This is the second most common bone disorder (after osteoporosis), and affects >5% of the over 55’s in the UK. The prevalence varies between countries and races. The UK has the highest incidence. It is rare in Scandinavia, China and Japan. Increased incidence in Pet Owners Genetic susceptibility  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
0
82

SLE - Systemic Lupus Erythematosus

SLE (Systemic Lupus Erythematosus) is an autoimmune connective tissue disease, similar to systemic sclerosis, RA, and mixed connective tissue disease. Often, symptoms of these diseases overlap. In cases where you unable to distinguish exactly which condition is present,we would normally say that mixed connective tissue disease is present.   Like those other disorders, ANA’s (anti-nuclear antibodies) can be found in blood of many affected patients.    
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
27

Systemic Sclerosis

Systemic sclerosis is an autoimmune connective tissue disorder. Other similar diseases include SLE, RA, Sjogren’s syndrome and mixed connective tissue disease. There is a lot of overlap in the symptoms of these diseases. Many will require immunosuppressive therapy.  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
30

Syndrome of Inappropriate ADH Secretion (SIADH)

 
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
27

Goitre

Summary Goitre - enlarged palpable thyroid gland, moves on swallowing Best way to assess is via USS Not necessarily indicative of disease Simple Goitre - normal level of hormones, no treatment necessary    
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
2
47

Autoantibodies

Quick summary of Autoantibodies   Antibody Disease  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
29

Haemophilia A

X-linked recessive condition, deficiency of factor VIII, prevalence 1 in 10,000 Range of possible mutations, 30% of cases due to sporadic mutation Low factor VIII levels predispose to bleeding – risk proportional to factor VIII level Mild disease (11-30 units/dl) risk after significant trauma/surgery Moderate disease (2-10 units) - minor trauma  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
26

Haemophilia B (Christmas Disease)

X-linked recessive condition, deficiency of factor IX Severely affected patients develop haemarthroses Inhibitors (factor IX antibodies) less common Recombinant factor IX – 18 hour half life so daily dosing to maintain levels Prophylactic treatment can be given once or twice weekly Named for the patient in the leading paper on the disease (Mr. Christmas), published in the BMJ Christmas edition 1952  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
48

von Willebrand's Disease

Most common inherited bleeding disorder (asymptomatic deficiencies 1%, symptomatic disease 100 per million) von Willeband factor (vWF) important in platelet adhesion and factor VIII transport Types of vWDType 1: decreased concentration of vWF, 80%, often autosomal dominantType 2: qualitative deficiency – AD or AR inheritance  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
5

Comparison and Summary of White Cell Disease

 
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
28

Large Bowel Obstruction

Large bowel obstruction Typically causes a less severe disease than small bowel obstruction Symptoms are more gradual in onset There are often loud borborygmi (normal bowel sounds) Rectum is usually empty, and the abdomen is non-tender Pain is lower down in the abdomen There may be greater distension than with small bowel obstruction    
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
41

Causes of Hepatomegaly

Causes of hepatomegalyMassive = CRAM Cancer - primary and secondary Right heart failure Alcoholic liver disease with fatty infiltration Myeloproliferative diseases (ie Chronic myeloid laekaemia, PRubraVera,Essential Throbocythaemia) Moderate = FAILL  all of the above plus Fatty liver - from DM, obesity Amyloidosis  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
20

Hepatitis C

This is unusual as hepatitis viruses go, as it very rarely causes acute infection. People will only become aware of infection when they develop serious liver disease later in life. 80% of those exposed to the virus will develop chronic infection. Spontaneous late clearance of the disease is very rare. Blood transfusion and blood products are a major means of transmission. It is also though that it can be sexually transmitted, but this is not particularly common.  
almostadoctor.com - free medical student revision notes
over 6 years ago
Preview
1
80

Hepatitis E

Hepatits E is clinically very similar to Hepatitis A.  Aetiology Water borne similar to hep A(shell fish and water melons!). 30% of dogs, rodents and pigs carry the virus Commonly seen in Asia and the Far East Presentation Very similar to that of hep A: Many patients are asymptomatic. They may never know they have had the disease Very rarely it can be lifethreatening May be a prodromal phase    
almostadoctor.com - free medical student revision notes
over 6 years ago