New to Meducation?
Sign up
Already signed up? Log In

Category

Preview
0
0

Frog foam could deliver drug therapy - BBC News

Foam made by miniature frogs to protect their eggs could offer a clever way to deliver healing drugs to burns patients, scientists believe.  
bbc.co.uk
over 3 years ago
Preview
0
0

U-turn over prostate cancer drug - BBC News

Patients with prostate cancer in England will now have early access to a drug that can delay the need for chemotherapy.  
bbc.co.uk
over 3 years ago
Preview
0
0

Test Spots Breast Cancer Patients Who Can Forgo Chemo

The 21-gene assay for breast cancer recurrence (Oncotype DX, Genomic Health) can help identify women with early breast cancer, including those with one to three positive nodes, who can safely skip chemotherapy, according to five-year results from the phase 3 PlanB study.  
medscape.com
over 3 years ago
Preview
0
0

Risky Drug Prescriptions Cut by Multipronged Intervention

Primary care prescribing of NSAIDs and antiplatelet agents for high-risk patients dropped with education, informatics, and financial incentives.  
medscape.com
over 3 years ago
Preview
0
0

Gene Expression Profiling for Cancer of Unknown Primary

Does the addition of everolimus to standard chemotherapy improve outcomes in cancer of unknown primary site?  
medscape.com
over 3 years ago
Preview
0
0

Crohn's, Colitis Congress Combines Original Research, Advice

Large, randomized trials on cell therapies, drug safety, the perioperative management of patients, and practical advice from experts from around the world will be highlighted at the congress.  
medscape.com
over 3 years ago
Preview
0
0

Medication Errors in Cardiac Arrest, Code-Related Situations

How often do medication-related errors occur during cardiopulmonary arrest and other related emergencies -- and what can be done to minimize them?  
medscape.com
over 3 years ago
Preview
0
0

Neoadjuvant Endocrine Therapy Underused for Breast Cancer

It does not work as fast as chemotherapy, but endocrine therapy increases breast conservation by downstaging disease.  
medscape.com
over 3 years ago
Preview
0
0

Don't Abandon Radiation, It Improves Survival in DLBCL

Large national US database supports a survival advantage for consolidation radiotherapy following chemotherapy over chemotherapy alone in early, diffuse, large B-cell lymphoma.  
medscape.com
over 3 years ago
Preview
0
0

You Do the Math(s) 5: Logarithms and Exponentials - Intensive Care Network

You Do the Math(s) 5: Logarithms and Exponentials Logarithms and Exponentials Basic Science Clinic Crit Think So mathematical truth prefers simple words since the language of truth is itself simple. Tycho Brahe Welcome to Basic Science Clinic, this is Crit think episode 5. Today our exploration of the mathematical architecture of our most inexact of sciences brings us upon the edifice of logarithms and exponentials. Daunting as it may sound, we will try to tease out their utility and relevance to critical care medicine and even attempt to penetrate the secrets of the mysterious number e. Logarithmic transformations permeate pharmacokinetic, biological and physiological modelling.  Exponentials are the inverse function of the logarithm, and the special properties of explosive exponential change in quantities has implications for ventilation, pharmacotherapy and beyond. Euler’s number, e, represents the idea that all continually growing systems are scaled versions of a common rate. Describing e as a constant approximating 2.718 is like calling pi an irrational number approximating 3.141. It’s true but it totally misses the point. Pi is the ratio between the circumference and diameter of every circle. It is a fundamental ratio and therefore impacts any calculation involving circumference, area, volume and surface area for all circles, spheres and cylinders. e is not just a number it is about the fundamental relationship between all growth rates. Thanks for listening. From The Happy Prince by Oscar Wilde: “I am so clever that sometimes I do not understand a single word of what I am saying.” Word of the day: evanescent Literary: soon passing out of sight, memory, or existence; quickly fading or disappearing. Physics: denoting a field or wave which extends into a region where it cannot propagate and whose amplitude therefore decreases with distance. For feedback, corrections and suggestions you can contact us on the twitter handles @falconzao and @sophmconnolly or post on Intensive Care Network. Next up is the last in this Crit Think: You Do the Math(s) series and we will examine the mathematics behind clinical measurement. The Podcast About the Authors  
intensivecarenetwork.com
over 3 years ago
Preview
0
0

An Evolutionary Approach: Learning to Live With Cancer

Instead of high-dose chemotherapy to shrink the tumor, a new approach suggests using adaptive therapy with low-dose chemotherapy.  
medscape.com
over 3 years ago
Preview
0
2

Benefits of Additional Chemo in Residual Breast Cancer

Drs Kathy Miller and Bryan Schneider discuss the surprising CREATE-X findings, which show improved survival using more chemotherapy in triple-negative breast cancer patients with residual disease.  
medscape.com
over 3 years ago
Preview
0
2

Treating HER2 Lung Cancers: The EUHER2 Cohort

Is trastuzumab beneficial in combination with chemotherapy for advanced HER2-positive advanced NSCLC?  
medscape.com
over 3 years ago
Preview
0
0

Laser treatment opens temporary window in blood-brain barrier

A laser system used to kill brain tumours also temporarily disrupts the blood-brain barrier, allowing chemotherapy drugs to pass into the brain for up to six weeks, finds a study published in PLoS One.1 The discovery may give doctors a window of opportunity to use drugs against glioblastoma that are normally ineffective, the researchers said.  
feeds.bmj.com
over 3 years ago
Preview
0
0

Pancreatic Cancer: Adjuvant Chemotherapy, but Not Radiation

In the treatment of resectable pancreatic cancer, addition of adjuvant chemotherapy, but not radiation, reduces the risk for distant recurrences, according to a retrospective analysis.  
medscape.com
over 3 years ago
Preview
0
0

Expert: Induction Chemo Has 'No Role' in H&N Cancer

A large new study adds to the evidence that for patients with advanced head and neck cancer, extensive chemotherapy long before radiation does not improve survival.  
medscape.com
over 3 years ago
Preview
0
0

Treating hypertension in patients with medical comorbidities

There is NICE guidance on blood pressure targets and drug therapy for patients with hypertension and comorbidities such as chronic kidney disease, diabetes, atrial fibrillation, and heart failure  
feeds.bmj.com
over 3 years ago
Preview
0
0

When Are Breast Cancer Patients at Highest Risk of Venous Thromboembolism? A Cohort Study Using English Health Care Data: Abstract and Introduction

Abstract and Introduction: Women receiving chemotherapy for breast cancer have a clinically important risk for venous thromboembolism; this increased risk immediately after endocrine therapy is restricted to tamoxifen.  
medscape.org
over 3 years ago
Preview
0
0

Updated CINV Guidelines: New Evidence for Change and Practical Issues CME/CE

This activity is intended for oncologists, nurses, and pharmacists, as well as other clinicians who treat patients at risk for or who experience chemotherapy-induced nausea and vomiting (CINV).  
medscape.org
over 3 years ago
Preview
1
1

A Survey on Polypharmacy and Use of Inappropriate Medications

In the past, polypharmacy was referred to the mixing of many drugs in one prescription. Today polypharmacy implies to the prescription of too many medications for an individual patient, with an associated higher risk of adverse drug reactions (ADRs) and interactions. Situations certainly exist where the combination therapy or polytherapy is the used for single disease condition. Polypharmacy is a problem of substantial importance, in terms of both direct medication costs and indirect medication costs resulting from drug-related morbidity. Polypharmacy increases the risk of side effects and interactions. Moreover it is a preventable problem. A retrospective study was carried out at Bhopal district (Capital of Madhya Pradesh, India) in the year of September-November 2009 by collecting prescriptions of consultants at various levels of health care. The tendency of polypharmacy was studied and analyzed under the various heads in the survey. Available data suggests that polypharmacy is a widespread problem, and physician, clinical pharmacists and patients are all responsible. These risks can be minimized through identifying the prevalence of this potential problem in a high-risk population and by increasing awareness among patients and healthcare professionals. Physicians and clinical pharmacists have the potential to combating this problem through a variety of interventions such as reducing the number of medications taken, reducing the number of doses taken, increasing patient adherence, preventing ADRs, improving patient quality of life and decreasing facility and drug costs.  
ncbi.nlm.nih.gov
over 3 years ago