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Pregnant woman with breast cancer 'must have baby early' - BBC News

A pregnant woman who chose to delay intensive chemotherapy rather than abort her baby is told she must have the child 12 weeks early to stand the best chance of surviving.  
bbc.co.uk
almost 4 years ago
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Midostaurin in AML: First Targeted Agent Improves Survival

The targeted agent was added onto chemotherapy in patients with acute myeloid leukemia and the FLT3 mutation (found in about 30% of cases).  
medscape.com
almost 4 years ago
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Rituximab + Chemo: New Standard of Care for BCP-ALL?

Adding rituximab to chemotherapy significantly improved event free survival in patients with B-cell precursor acute lymphoblastic leukemia (BCP-ALL).  
medscape.com
almost 4 years ago
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Chemotherapy for Germ Cell Tumor May Spur CML

Findings raise the question of a causal link between etoposide and/or platinum-containing chemotherapy and the development of chronic myelogenous leukemia (CML).  
medscape.com
almost 4 years ago
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Chemotherapy-Induced Peripheral Neurotoxicity

This review summarizes the typical clinical features of different neurotoxic anticancer drugs. Can their neurotoxic effects be prevented or minimized?  
medscape.com
almost 4 years ago
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Cost-effectiveness of Sofosbuvir for Chronic HCV

Is sofosbuvir considered to be a cost-effective drug therapy for chronic HCV, and how does it compare to other regimens?  
medscape.com
almost 4 years ago
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Jackson Heart: Major Depression Ups Stroke, CHD Risk in Blacks

Investigators note the need for greater understanding of these associations "in light of reported racial disparities in disease severity, timely diagnosis, and use of pharmacotherapy."  
medscape.com
almost 4 years ago
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Necitumumab (Portrazza) Approved for Lung Cancer in US

The novel product, a monoclonal antibody against EGFR, is approved for use with chemotherapy in patients with squamous non-small cell lung cancer (NSCLC).  
medscape.com
almost 4 years ago
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Elderly Cancer Patients: QOL, Polypharmacy, and Survivorship

At the European Cancer Congress, clinicians discussed the heterogeneity of elderly patients, polypharmacy, and other factors that complicate the treatment of older people with cancer.  
medscape.com
almost 4 years ago
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Platelet transfusions are used to prevent bleeding in people with low platelet counts due to treatment-induced bone marrow failure | Cochrane

We evaluated the evidence about whether platelet transfusions given to prevent bleeding in people with lower platelet counts (for example 5 x 109/L or below) were as effective and safe as the current standard (10 x 109/L or below), or whether higher platelet count levels (20 x 109/L or below, 30 x 109/L or below, or 50 x 109/L or below) were safer than the current standard (10 x 109/L or below). Our target population was people with blood cancers (for example leukaemia, lymphoma, myeloma) who were receiving intensive (myelosuppressive) chemotherapy treatments or stem cell transplantation.  
cochrane.org
almost 4 years ago
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Blood-Brain Barrier Safely Breached

Doctors have been able to safely penetrate the blood-brain barrier and deliver a chemotherapy drug directly into the brain of a woman with glioblastoma.  
medscape.com
almost 4 years ago
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Cannabis-based medicine for nausea and vomiting in people treated with chemotherapy for cancer | Cochrane

Background As many as three-quarters of people who receive chemotherapy experience nausea (feeling sick) and vomiting (being sick), which many find distressing. While conventional anti-sickness medicines are effective, they do not work for everyone, all of the time. Therapeutic drugs based on the active ingredient of cannabis, known as THC (delta-9-tetrahydrocannabinol), have been approved for use as anti-sickness medicines in some countries.  
cochrane.org
almost 4 years ago
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Deeper Grasp of Chemotherapy-Induced Peripheral Neuropathy

Two unrelated studies provide deeper insights into chemotherapy-induced peripheral neuropathy.  
medscape.com
almost 4 years ago
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Radiotherapy Confers No Additional Benefit for Mesothelioma

A randomized trial shows no extra benefit from adding radiotherapy after surgery and neoadjuvant chemotherapy for mesothelioma.  
medscape.com
almost 4 years ago
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Perioperative Medication Errors Plague Surgeries

Previous literature on perioperative medication error rates underestimated true error rates, according to a new prospective study.  
medscape.com
almost 4 years ago
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Victoria Derbyshire breast cancer diary: First chemo cycle - BBC News

BBC presenter Victoria Derbyshire records a video diary of her first cycle of chemotherapy after being diagnosed with breast cancer in July.  
bbc.co.uk
almost 4 years ago
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Scientists breach brain barrier to treat sick patient - BBC News

For the first time, doctors breach the human brain's protective layer to deliver chemotherapy to a tumour.  
bbc.co.uk
almost 4 years ago
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Barium enema in Hirschprung's disease

Prepare for USMLE,UK,CANADIAN,AUSTRALIAN, NURSING & OTHER MEDICAL BOARD examinations around the globe with us.Understand the basics, concepts and how to answ...  
youtube.com
almost 4 years ago
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Genetic Variations Linked to Chemotherapy Damage for Ovaries

Genetic variations are associated with post-treatment ovarian function in young breast cancer patients receiving cyclophosphamide, new data suggest.  
medscape.com
almost 4 years ago
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The role of interleukin-2 as maintenance therapy in children and adults with acute myeloid leukaemia in first complete remission | Cochrane

Acute myeloid leukaemia (AML) is a malignant cancer of blood cells. Most people with AML are subjected to chemotherapy or bone marrow transplantation to eliminate cancer cells. In response to these treatments, people might achieve complete remission (CR), the status without cancer cells in blood and signs of blood cancer. Although the disease is well controlled at the beginning of the treatment, AML may return, progress again, and result in unsatisfactory life expectancy. People in CR still need to receive further treatment. Interleukin-2 (IL-2) is an alternative as maintenance therapy to maintain the curative effect and deter disease progression. Clinical results have been published comparing the use of IL-2 and no maintenance therapy in people who had achieved CR, but the effect of IL-2 remains unclear.  
cochrane.org
almost 4 years ago