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Another patient with low back pain

A 52 year old man was admitted to our oncology unit owing to the side effects of ongoing chemotherapy; he also gave a 10 day history of back pain. In 2008, after a bowel resection for colonic obstruction, he had been diagnosed with diffuse large B cell lymphoma. This was treated with eight cycles of R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone) and a complete response was achieved.  
feeds.bmj.com
over 4 years ago
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14

Local physician recommends World Health Organization retire the term opioid substitution therapy

A Boston researcher and physician caring for individuals with substance abuse disorders, believes the term opioid substitution therapy (OST) has unintended adverse consequences for patients...  
medicalnewstoday.com
over 4 years ago
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9

Studies report new findings on treatment options for mesothelioma

Treating patients with high-dose radiotherapy after chemotherapy and surgery for malignant pleural mesothelioma does not achieve improvements in local relapse and overall survival, according...  
medicalnewstoday.com
over 4 years ago
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1

Certain fish oils 'may induce chemoresistance in cancer patients'

Taking certain fish oil supplements or eating herring or mackerel may increase the risk of chemotherapy resistance for cancer patients, a new study suggests.  
medicalnewstoday.com
over 4 years ago
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9

Gene signatures predict doxorubicin response in K9 osteosarcoma

COXEN gene expression model matches dogs with bone cancer to most effective drugThere are two chemotherapies commonly used to treat bone cancer in dogs: doxorubicin and...  
medicalnewstoday.com
over 4 years ago
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2

Blood test can help some bowel cancer patients avoid unnecessary drug side-effects

Manchester researchers have provided early evidence to suggest that a blood test could be used to identify bowel cancer patients that may benefit from more intensive chemotherapy.  
medicalnewstoday.com
over 4 years ago
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5

Researchers solve science behind scalp cooling and the reasons for hair loss in cancer treatment

Hair loss is one of the most distressing side-effects of cancer treatment and can even deter some patients from undergoing life-saving chemotherapy.  
medicalnewstoday.com
over 4 years ago
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4

Managing IBS effectively with the right drugs, for the right symptoms

Up to 15 percent of the general adult population is affected by irritable bowel syndrome (IBS), and most patients struggle to find effective drug therapy.  
medicalnewstoday.com
over 4 years ago
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10

Nanoparticles carry drugs selectively to lung tumor sites

Scientists have created nanocarriers that can selectively deliver chemotherapy drugs locally to lung tumor sites without touching healthy tissue, potentially reducing side effects.  
medicalnewstoday.com
over 4 years ago
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2

Hormone Replacement Therapy for postmenopausal women: Does it help or harm your heart?

New evidence published in the Cochrane Library shows that hormone replacement therapy does not protect post-menopausal women against cardiovascular disease, and may even cause an increased...  
medicalnewstoday.com
over 4 years ago
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5

Sugar-seeking MRI could be used to detect early-stage cancer

Johns Hopkins researchers are trialling a new MRI technique to detect early-stage cancer, guide biopsies and monitor chemotherapy response.  
medicalnewstoday.com
over 4 years ago
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2

Seeking new targets for ovarian cancer treatment

Identifying molecular changes that occur in tissue after chemotherapy could be crucial in advancing treatments for ovarian cancer, according to research from Magee-Womens Research Institute and...  
medicalnewstoday.com
over 4 years ago
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2

Magee, UPCI researchers seek new targets for ovarian cancer treatment

Identifying molecular changes that occur in tissue after chemotherapy could be crucial in advancing treatments for ovarian cancer, according to research from Magee-Womens Research Institute...  
medicalnewstoday.com
over 4 years ago
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1

Women with ovarian cancer gain extra months with addition of drug to standard chemotherapy

Medical researchers are always looking for ways to prevent or cure cancer. Given the complexity of this disease, reaching these milestones has been difficult.  
medicalnewstoday.com
over 4 years ago
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1

Ovarian cancer treatment set to improve following biomarker discovery

The discovery of a biomarker that predicts the response to chemotherapy in patients with the most malignant form of ovarian cancer will help lead to better treatment options.  
medicalnewstoday.com
over 4 years ago
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9

Label design may affect risk of medication errors in OR, reports Journal of Patient Safety

Redesigned labels reduce the number of errors in simulated surgical emergency, study findsSpecial redesigned labels for intravenous (IV) medication bags may help to...  
medicalnewstoday.com
over 4 years ago
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0
2

Concurrent chemoradiation treatment at high-volume facilities improves survival for NSCLC

Patients treated with definitive concurrent chemotherapy and radiation therapy (CCRT) for stage III non-small cell lung cancer (NSCLC) have longer overall survival when treated by highly...  
medicalnewstoday.com
over 4 years ago
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17

Avoiding Resuscitation Medication Errors - Part I

I am joined by Bryan Hayes to discuss the avoidance of critical medication errors during resuscitations.  
emcrit.org
over 4 years ago
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9

Cancer vaccines

Cancer vaccines are designed to promote tumor specific immune responses, particularly cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines, which were developed in 1994-95, tested non-mutated, shared tumor associated antigens that had been shown to be immunogenic and capable of inducing clinical responses in a minority of people with late stage cancer. Technological developments in the past few years have enabled the investigation of vaccines that target mutated antigens that are patient specific. Several platforms for cancer vaccination are being tested, including peptides, proteins, antigen presenting cells, tumor cells, and viral vectors. Standard of care treatments, such as surgery and ablation, chemotherapy, and radiotherapy, can also induce antitumor immunity, thereby having cancer vaccine effects. The monitoring of patients’ immune responses at baseline and after standard of care treatment is shedding light on immune biomarkers. Combination therapies are being tested in clinical trials and are likely to be the best approach to improving patient outcomes.  
feeds.bmj.com
over 4 years ago
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0
13

Cancer vaccines

Cancer vaccines are designed to promote tumor specific immune responses, particularly cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines, which were developed in 1994-95, tested non-mutated, shared tumor associated antigens that had been shown to be immunogenic and capable of inducing clinical responses in a minority of people with late stage cancer. Technological developments in the past few years have enabled the investigation of vaccines that target mutated antigens that are patient specific. Several platforms for cancer vaccination are being tested, including peptides, proteins, antigen presenting cells, tumor cells, and viral vectors. Standard of care treatments, such as surgery and ablation, chemotherapy, and radiotherapy, can also induce antitumor immunity, thereby having cancer vaccine effects. The monitoring of patients’ immune responses at baseline and after standard of care treatment is shedding light on immune biomarkers. Combination therapies are being tested in clinical trials and are likely to be the best approach to improving patient outcomes.  
feeds.bmj.com
over 4 years ago