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Neratinib Keeps Benefiting Herceptin-Treated Breast Cancer

New results from the ExteNET study of the investigational drug neratinib following adjuvant trastuzumab chemotherapy confirm a benefit of the agent beyond the previously reported 2-year results.  
medscape.com
about 4 years ago
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Pharmacists Play Key Role in Mitigating Medication Errors

Human and system errors during code situations are frequent, but pharmacists can have a protective effect.  
medscape.com
about 4 years ago
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Carboplatin for Early TNBC? Depends on Who You Ask

The benefits of adding carboplatin to first-line chemotherapy for early-stage triple-negative breast cancer are still unclear, but certain patients are a better fit, according to new data.  
medscape.com
about 4 years ago
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Toward a Chemotherapy-Free Future for CLL

Drs Bruce Cheson and Kanti Rai discuss some of the highlights in chronic lymphocytic leukemia clinical research from the 2015 American Society of Hematology meeting.  
medscape.com
about 4 years ago
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Herceptin Affirmed, Anthracyclines Questioned in Major Trial

The landmark BIRCG-006 trial that helped establish trastuzumab as a standard for early-stage HER2-positive breast cancer continues to stir debate over which chemotherapy to pair it with.  
medscape.com
about 4 years ago
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Managing Nursing Home Residents With Overactive Bladder

The prevalence of urinary incontinence and OAB is high in both male and female nursing home residents, but optimization of pharmacotherapy is difficult due to drug- and drug-disease interactions.  
medscape.com
about 4 years ago
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LHRHa Preserves Ovarian Function in Breast Cancer Chemo

Adding the hormonal drug triptorelin to chemotherapy in premenopausal women with breast cancer to achieve ovarian suppression may preserve their ovarian function.  
medscape.com
about 4 years ago
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MMR Status and Response to Chemotherapy in Pancreatic Cancer

Does mismatch repair status influence the natural course of pancreatic ductal adenocarcinoma or its response to pyrimidine-based chemotherapy?  
medscape.com
about 4 years ago
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Hormone treatment may help prevent premature menopause in cancer patients

Young women with breast cancer who are given a luteinising hormone releasing hormone (LHRH) analogue, triptorelin, alongside chemotherapy are more likely to retain ovarian function, a study in JAMA shows.1  
feeds.bmj.com
about 4 years ago
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Malignant Pleural Effusion Pleurodesis Strategies

Results of a controlled trial challenge current guidelines that support avoiding nonsteroidal anti-inflammatory drugs (NSAIDs) and use of small chest tubes in patients with malignant pleural effusions undergoing pleurodesis, the researchers say.  
medscape.com
about 4 years ago
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Natural History and Outcome of Light Chain Deposition Disease: Abstract and Introduction

Abstract and Introduction: In patients with light chain deposition disease, deep clonal responses to chemotherapy are associated with improved outcomes and should be targeted, even in patients with advanced chronic kidney disease.  
medscape.org
about 4 years ago
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Victoria Derbyshire breast cancer diary part three: Hair loss - BBC News

BBC journalist Victoria Derbyshire has revealed she is now wearing a wig, following the hair loss caused by chemotherapy treatment for breast cancer.  
bbc.co.uk
about 4 years ago
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Mortality and Drug Therapy in Patients With COPD

Find out how different pharmacological COPD treatments impact overall survival. Which ones were shown to reduce mortality?  
medscape.com
about 4 years ago
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Risk of Heart Damage Follows Some Childhood Cancer Survivors

Childhood cancer survivors may face an increased risk of heart damage after exposure to certain chemotherapy and radiation treatments, a U.S. analysis suggests.  
medscape.com
about 4 years ago
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After Great Pain, a Cold Cap for Chemo Hair Loss Came

Refrigeration expertise and anguish from the adverse effects of breast cancer chemotherapy came together in a British family, and gave rise to technologic innovation.  
medscape.com
about 4 years ago
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Persistent Chemo-Induced Neuropathy Impacts Functioning

Chemotherapy-induced peripheral neuropathy can affect physical functioning years after treatment ends, and has been associated with a nearly twofold higher risk for falls.  
medscape.com
about 4 years ago
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Can Gonads Be Protected During Chemotherapy?

Can the use of gonadotropin-releasing hormone analogue during chemotherapy protect the ovaries from gonadal toxicity and preserve fertility?  
medscape.com
about 4 years ago
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Sisters help launch cancer study aiming to end chemotherapy - BBC News

The first patients have had their DNA analysed in a massive study that aims to replace chemotherapy.  
bbc.co.uk
about 4 years ago
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Chemotherapy could make breast cancer patients more vulnerable to common infections

Patients with breast cancer who are treated with chemotherapy have depleted immune systems, leaving them vulnerable to common infections, researchers have warned in the journal Breast Cancer Research.1 They said that revaccination against common immunogens may need to be considered in some cases.  
feeds.bmj.com
about 4 years ago
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Advances in Infusion Technology: Emerging Concepts in Chemotherapy and Supportive Care CME/CE

John P. Leonard, MD (Activity Moderator); Val R. Adams, PharmD, FCCP, BCOP; Barbara Barnes Rogers, CRNP, MN, AOCN, ANP-BC  
medscape.org
about 4 years ago