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Epidemiology

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Tuberculosis Caused by Mycobacterium africanum, United States, 2004-2013: Abstract and Introduction

Abstract and Introduction: This data study provides new details regarding the epidemiology and clinical presentation of Mycobacterium africanum infection.  
medscape.org
over 3 years ago
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6

Epidemiology of Histoplasmosis Outbreaks, United States, 1938–2013: Abstract and Introduction

Abstract and Introduction: A literature review describes features of reported histoplasmosis outbreaks during 1938-2013 in the United States and urges improved awareness of the disease and prevention strategies.  
medscape.org
over 3 years ago
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7

Antibiotic resistance in Enterobacteriaceae: mechanisms and clinical implications

Resistance of the Enterobacteriaceae to antibiotics, especially of the β lactam type, is increasingly dominated by the mobilization of continuously expressed single genes that encode efficient drug modifying enzymes. Strong and ubiquitous selection pressure has seemingly been accompanied by a shift from “natural” resistance, such as inducible chromosomal enzymes, membrane impermeability, and drug efflux, to the modern paradigm of mobile gene pools that largely determine the epidemiology of modern antibiotic resistance. In this way, antibiotic resistance is more available than ever before to organisms such as Escherichia coli and Klebsiella pneumoniae that are important causes of major sepsis. Modulation of the phenotype by host bacteria makes gene transmission less obvious and may in part explain why tracking and control of carbapenem resistance has been particularly problematic in the Enterobacteriaceae. This review discusses the underlying principles and clinical implications of the mobility and fixation of resistance genes and the exploitable opportunities and potential threats arising from apparent limitations on diversity in these mobile gene pools. It also provides some illustrative paradoxes and clinical corollaries, as well as a summary of future options.  
feeds.bmj.com
over 3 years ago
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35

Antibiotic resistance in Enterobacteriaceae: mechanisms and clinical implications

Resistance of the Enterobacteriaceae to antibiotics, especially of the β lactam type, is increasingly dominated by the mobilization of continuously expressed single genes that encode efficient drug modifying enzymes. Strong and ubiquitous selection pressure has seemingly been accompanied by a shift from “natural” resistance, such as inducible chromosomal enzymes, membrane impermeability, and drug efflux, to the modern paradigm of mobile gene pools that largely determine the epidemiology of modern antibiotic resistance. In this way, antibiotic resistance is more available than ever before to organisms such as Escherichia coli and Klebsiella pneumoniae that are important causes of major sepsis. Modulation of the phenotype by host bacteria makes gene transmission less obvious and may in part explain why tracking and control of carbapenem resistance has been particularly problematic in the Enterobacteriaceae. This review discusses the underlying principles and clinical implications of the mobility and fixation of resistance genes and the exploitable opportunities and potential threats arising from apparent limitations on diversity in these mobile gene pools. It also provides some illustrative paradoxes and clinical corollaries, as well as a summary of future options.  
feeds.bmj.com
over 3 years ago
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Surveillance Systems for Sexually Transmitted Infections

What are the recent trends in STI epidemiology? Take a look at the disease surveillance data from regions around the globe to find out.  
medscape.com
over 3 years ago
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Critical Care

Two clinical scoring systems, the status epilepticus severity score (STESS) and the epidemiology-based mortality score in status epilepticus (EMSE), are used to predict mortality in patients with status epilepticus (SE). The aim of this study was to compare the outcome-prediction function of the two scoring systems regarding in-hospital mortality using a multicenter large cohort of adult patients with SE. Moreover, we studied the potential role of these two scoring systems in predicting the functional outcome in patients with SE.  
ccforum.biomedcentral.com
over 3 years ago
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1

Decisions on restarting anticoagulation should be made earlier after rebleeding

Staerk and colleagues’ paper provides support for the important, perhaps underused, practice of reintroducing anticoagulation after a gastrointestinal haemorrhage.1 Some aspects of the paper need to be put into context. The data on antiplatelet agents for atrial fibrillation have little relevance to current practice because the management and epidemiology of gastrointestinal bleeding has changed over the course of the study (1996-2012). Improvements in endoscopic and medical management have …  
feeds.bmj.com
over 3 years ago
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0

Decisions on restarting anticoagulation should be made earlier after rebleeding

Staerk and colleagues’ paper provides support for the important, perhaps underused, practice of reintroducing anticoagulation after a gastrointestinal haemorrhage.1 Some aspects of the paper need to be put into context. The data on antiplatelet agents for atrial fibrillation have little relevance to current practice because the management and epidemiology of gastrointestinal bleeding has changed over the course of the study (1996-2012). Improvements in endoscopic and medical management have …  
feeds.bmj.com
over 3 years ago
Preview
0
0

Decisions on restarting anticoagulation should be made earlier after rebleeding

Staerk and colleagues’ paper provides support for the important, perhaps underused, practice of reintroducing anticoagulation after a gastrointestinal haemorrhage.1 Some aspects of the paper need to be put into context. The data on antiplatelet agents for atrial fibrillation have little relevance to current practice because the management and epidemiology of gastrointestinal bleeding has changed over the course of the study (1996-2012). Improvements in endoscopic and medical management have …  
feeds.bmj.com
over 3 years ago
Preview
0
0

Decisions on restarting anticoagulation should be made earlier after rebleeding

Staerk and colleagues’ paper provides support for the important, perhaps underused, practice of reintroducing anticoagulation after a gastrointestinal haemorrhage.1 Some aspects of the paper need to be put into context. The data on antiplatelet agents for atrial fibrillation have little relevance to current practice because the management and epidemiology of gastrointestinal bleeding has changed over the course of the study (1996-2012). Improvements in endoscopic and medical management have …  
feeds.bmj.com
over 3 years ago
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0

Management of Chronic Hepatitis B: An Overview

This review reviews the epidemiology and clinical course of chronic hepatitis B, summarizing current management recommendations and presenting a simple treatment algorithm.  
medscape.com
over 3 years ago
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Epidemiology of Haemophilus ducreyi Infections: Abstract and Introduction

Abstract and Introduction: This activity is intended for primary care physicians, infectious disease specialists, obstetrician-gynecologists, and other physicians who may see patients with genital ulcer disease.  
medscape.org
over 3 years ago
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Prehospital management of Zombies

Zombie infections: epidemiology, treatment, and prevention | best #FOAMed paper this year, by far! :) https://t.co/KAI1UQ2Zus — Youri Yordanov (@YordaYou) December 15, 2015 Attribution to this joker  
prehospitalmed.com
over 3 years ago
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5

Zombie infections: epidemiology, treatment, and prevention

Tara C Smith summarises the epidemiology and pathology of zombie infections and calls for research and funding to prevent a zombie apocalypse  
feeds.bmj.com
over 3 years ago
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9
1078

Intro to Systematic Reviews & Meta-Analyses

Here's a brief introduction to how to evaluate systematic reviews.  
youtube.com
almost 4 years ago
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Hip pain and radiographic signs of osteoarthritis

Hip pain is common, particularly among adults older than 50 years, and intuitively linked to osteoarthritis. Osteoarthritis refers to a heterogeneous group of joint disorders characterised by progressive destruction of cartilage. Patients present with activity related joint pain and stiffness.1 2 Osteoarthritis can be classified as primary or secondary, but in practice and research the diagnosis is more often categorised as radiographic osteoarthritis, self reported osteoarthritis, or clinical (symptomatic) osteoarthritis. These designations have substantially different prevalences and incidences.2 3 4 Since osteoarthritis is a leading cause of pain and disability, we clearly need a better understanding of its epidemiology, and we need better methods for identifying patients at risk of the debilitating consequences of progressive limitations to daily life caused by symptomatic disease.1 2 5 6  
feeds.bmj.com
almost 4 years ago
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9
820

An Introduction to Ischemic Stroke

In this first video on ischemic stroke, we'll look at some of the epidemiology of stroke - it's a pretty devastating disease on our population.  
youtube.com
almost 4 years ago
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5
156

Introduction to Epidemiology and public health

Great slideshow on Epidemiology - the basics.  
youtube.com
almost 4 years ago
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Smoking and Seizures: Where the Evidence Stands

Dr Wilner describes the epidemiology of smoking among people with epilepsy, the potential effects of nicotine on seizures, and seizure risks among smoking cessation medications.  
medscape.com
almost 4 years ago
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9
271

Psychiatry Lecture: Anxiety Disorders

A presentation on ‘Anxiety Disorders’ that systematically goes through the Clinical features, Epidemiology, Aetiology, Management and Prognosis of the follow...  
youtube.com
almost 4 years ago