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7

Lung Cancer Sessions Focus on Immunotherapy, Genomics

From diagnosis using molecular markers to targeted treatment, Dr Mark Kris details which studies from ASCO 2016 he thinks will help clinicians and patients fight lung cancer.  
medscape.com
about 4 years ago
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9

Precision Medicine and Research Ethics

Precision medicine is improving through genetics and genomics research, but also raises new ethical challenges.  
medscape.com
about 4 years ago
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7

Genetics and Psychiatry: Let's Proceed With Caution

Dr Lieberman discusses three publications that illustrate the increasing role of genomics in psychiatry, cautioning against getting too excited too soon.  
medscape.com
about 4 years ago
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1

MicroRNAs Regulate Schizophrenia Risk Genes

Several microRNAs (miRNAs) regulate key schizophrenia risk genes, according to research from the Psychiatric Genomics Consortium.  
medscape.com
about 4 years ago
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1

Chopra, Tanzi: Devices Will Reduce Disease, Alter Medicine

Electronics can help people reprogram their DNA and transform their health, and genomics, lifestyle, and environmental technology is converging to create ways to accurately target and treat disease.  
medscape.com
over 4 years ago
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1

Epigenetics in the Pathogenesis of Systemic Sclerosis

This review examines the significant role of epigenetic modifications in the pathogenesis of systemic sclerosis.  
medscape.com
over 4 years ago
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1

Schizophrenia Tied to Epigenetic Changes Before Birth

Two new studies add weight to the hypothesis that schizophrenia has its origins before birth.  
medscape.com
over 4 years ago
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Precision Medicine: Who Will Own the Data?

At Medscape's first Medicine 3.0 conference, Editor-in-Chief Eric Topol leads a panel discussion on how to make medicine more precise, stressing that it's not always about genomics.  
medscape.com
over 4 years ago
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Precision Medicine: More Understanding, Better Treatments

At Medscape's first Medicine 3.0 conference, Editor-in-Chief Eric Topol leads a panel discussion on how to make medicine more precise, stressing that it's not always about genomics.  
medscape.com
over 4 years ago
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7

Huge Cancer Research Fraud, But Only One Doc Blamed

Why has only one researcher has been punished for the false research in cancer genomics at Duke University that led to clinical trials in hundreds of patients?  
medscape.com
over 4 years ago
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1

Exponential Medicine 2015 Day 1: Genomics, Big Data, AI, and Bitcoin? |

Welcome back for Medgadget's coverage of Exponential Medicine in San Diego, CA, a Singularity University event. Exponential Medicine promises four days of  
medgadget.com
over 4 years ago
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Former Duke University oncologist is guilty of research misconduct, US officials find

A cancer genomics researcher, whose reported findings appeared in some of the world’s most prestigious journals and prompted the initiation of several clinical trials, has been found guilty of research misconduct by the US Department of Health and Human Services’ Office of Research Integrity (ORI).  
feeds.bmj.com
over 4 years ago
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First Clinical Single Molecule Genome Sequencer Unveiled |

According to claims by Direct Genomics, a Chinese firm, it is introducing the first single molecule DNA sequencer for clinical use that does not require an  
medgadget.com
over 4 years ago
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Critical Care

Epigenetics is the study of how cells, organs, and even individuals utilize their genes over specific periods of time, and under specific environmental constraints. Very importantly, epigenetics is now expanding into the field of medicine and hence should provide new information for the development of drugs. Bomsztyk and colleagues have detected major epigenetic changes occurring in several organs as early as 6 h after the onset of a mouse model of multiple organ dysfunction syndrome induced by Staphylococcus aureus lung injury. Decrease in mRNA of key genes involved in endothelial function was found to be associated with (and potentially explained by) a decrease in permissive histone marks, while repressive marks were unchanged. We discuss here the limitations of a whole-organ as opposed to a cell-specific approach, the nature of the controls that were chosen, and the pitfalls of histone modifications as a cause of the eventual phenotype. While the use of ‘epidrugs’ is definitely welcome in the clinic, how and when they will be used in sepsis-related multiple organ dysfunction will require further experimental studies.  
ccforum.com
over 4 years ago
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New Clues That Sexual Orientation Could Be Epigenetic

Investigators have developed a preliminary biomarker-based model that predicts the sexual orientation of men.  
medscape.com
over 4 years ago
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16

WCLC Presidential Symposium: Summary, Clinical Implications

Dr Gilberto Lopes reviews the four top abstracts from the 16th World Conference on Lung Cancer, including treatments for NSCLC as well as genomics and lung cancer prevention.  
medscape.com
over 4 years ago