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Antenatal administration of corticosteroids for women at risk of preterm birth

The administration of certain corticosteroids to women at risk of preterm birth causes a considerable reduction in the risks of complications of prematurity such as respiratory distress syndrome, intraventricular haemorrhage and perinatal death. Corticosteroid therapy should be incorporated into comprehensive maternal health care services and official guidelines for maternity care.  
apps.who.int
almost 4 years ago
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Briefs: Neither pyogenic nor granuloma

A concerned mom presents with her daughter who has the following lesion on her left cheek that has enlarged over the past month and today wouldn’t stop bleeding at daycare. It started as a red dot a few months back and has grown steadily.  
pemcincinnati.com
about 4 years ago
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Upper Gastrointestinal Hemorrhage: An Update

What are the latest evidence-based recommendations for the management of acute upper GI hemorrhage?  
medscape.com
about 4 years ago
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Decisions on restarting anticoagulation should be made earlier after rebleeding

Staerk and colleagues’ paper provides support for the important, perhaps underused, practice of reintroducing anticoagulation after a gastrointestinal haemorrhage.1 Some aspects of the paper need to be put into context. The data on antiplatelet agents for atrial fibrillation have little relevance to current practice because the management and epidemiology of gastrointestinal bleeding has changed over the course of the study (1996-2012). Improvements in endoscopic and medical management have …  
feeds.bmj.com
about 4 years ago
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Decisions on restarting anticoagulation should be made earlier after rebleeding

Staerk and colleagues’ paper provides support for the important, perhaps underused, practice of reintroducing anticoagulation after a gastrointestinal haemorrhage.1 Some aspects of the paper need to be put into context. The data on antiplatelet agents for atrial fibrillation have little relevance to current practice because the management and epidemiology of gastrointestinal bleeding has changed over the course of the study (1996-2012). Improvements in endoscopic and medical management have …  
feeds.bmj.com
about 4 years ago
Preview
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0

Decisions on restarting anticoagulation should be made earlier after rebleeding

Staerk and colleagues’ paper provides support for the important, perhaps underused, practice of reintroducing anticoagulation after a gastrointestinal haemorrhage.1 Some aspects of the paper need to be put into context. The data on antiplatelet agents for atrial fibrillation have little relevance to current practice because the management and epidemiology of gastrointestinal bleeding has changed over the course of the study (1996-2012). Improvements in endoscopic and medical management have …  
feeds.bmj.com
about 4 years ago
Preview
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0

Decisions on restarting anticoagulation should be made earlier after rebleeding

Staerk and colleagues’ paper provides support for the important, perhaps underused, practice of reintroducing anticoagulation after a gastrointestinal haemorrhage.1 Some aspects of the paper need to be put into context. The data on antiplatelet agents for atrial fibrillation have little relevance to current practice because the management and epidemiology of gastrointestinal bleeding has changed over the course of the study (1996-2012). Improvements in endoscopic and medical management have …  
feeds.bmj.com
about 4 years ago
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VTE Risk After Receiving PCC for Intracranial Hemorrhage

Prothrombin complex concentrates are commonly used for the reversal of coagulopathy in warfarin-associated intracranial hemorrhage, but there may be a greater risk for VTE in some patients.  
medscape.com
about 4 years ago
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ORBIT: A Simple Bedside Score to Assess Bleeding Risk in AF

The authors present a novel bleeding risk score using routinely available clinical information to predict major bleeding in patients with atrial fibrillation.  
medscape.com
about 4 years ago
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Less Bleeding on Rivaroxaban for AF if Fewer Concomitant Meds

Taking five or more meds is common in patients with AF, but for those taking fewer than that, the risk of bleeding was lower with rivaroxaban than with warfarin, in a new analysis of ROCKET-AF.  
medscape.com
about 4 years ago
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14

Misoprostol - Wikipedia, the free encyclopedia

Misoprostol, sold under the brandname Cytotec among others, is a medication used to start labor, cause an abortion, prevent and treat stomach ulcers, and treat postpartum bleeding due to poor contraction of the uterus.[1] For abortions it is often used with mifepristone or methotrexate.[2] By itself effectiveness for this purpose is between 66% and 90%.[3] It is taken either by mouth, under the tongue, or placed in the vagina.[2][4]  
en.wikipedia.org
about 4 years ago
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Fibrin Sealant Patch Provides Better Hemostasis During Liver Resection

Fibrin sealant patches (FSP) provide better secondary control of local bleeding than cellulose patches in patients undergoing liver resection, researchers report.  
medscape.com
about 4 years ago
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Newer antiplatelet agents in acute coronary syndrome

Dual antiplatelet therapy comprising aspirin and a purinergic P2Y12 receptor inhibitor has long been the standard of care in patients with acute coronary syndrome (ACS). Clopidogrel is the most commonly used P2Y12 inhibitor,1 but its usefulness has been questioned, with 25-30% of patients achieving <25% inhibition of platelet activity. Moreover, onset (4-6 hours, even after a loading dose) and offset (5-7 days, the lifetime of platelets) of its activity are relatively slow. This slow offset is due to its irreversible binding to the P2Y12 receptor and may assume importance in patients with bleeding complications or in those requiring urgent surgical intervention. Slow onset is disadvantageous in patients with ACS, owing to the potential for propagation of thrombus in the interval until P2Y12 inhibition occurs.  
feeds.bmj.com
about 4 years ago
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Newer antiplatelet agents in acute coronary syndrome

Dual antiplatelet therapy comprising aspirin and a purinergic P2Y12 receptor inhibitor has long been the standard of care in patients with acute coronary syndrome (ACS). Clopidogrel is the most commonly used P2Y12 inhibitor,1 but its usefulness has been questioned, with 25-30% of patients achieving <25% inhibition of platelet activity. Moreover, onset (4-6 hours, even after a loading dose) and offset (5-7 days, the lifetime of platelets) of its activity are relatively slow. This slow offset is due to its irreversible binding to the P2Y12 receptor and may assume importance in patients with bleeding complications or in those requiring urgent surgical intervention. Slow onset is disadvantageous in patients with ACS, owing to the potential for propagation of thrombus in the interval until P2Y12 inhibition occurs.  
feeds.bmj.com
about 4 years ago
Preview
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Newer antiplatelet agents in acute coronary syndrome

Dual antiplatelet therapy comprising aspirin and a purinergic P2Y12 receptor inhibitor has long been the standard of care in patients with acute coronary syndrome (ACS). Clopidogrel is the most commonly used P2Y12 inhibitor,1 but its usefulness has been questioned, with 25-30% of patients achieving <25% inhibition of platelet activity. Moreover, onset (4-6 hours, even after a loading dose) and offset (5-7 days, the lifetime of platelets) of its activity are relatively slow. This slow offset is due to its irreversible binding to the P2Y12 receptor and may assume importance in patients with bleeding complications or in those requiring urgent surgical intervention. Slow onset is disadvantageous in patients with ACS, owing to the potential for propagation of thrombus in the interval until P2Y12 inhibition occurs.  
feeds.bmj.com
about 4 years ago
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Preop Anticoagulation Safe, Reduces DVTs in Cancer Patients

Preoperative use of anticoagulants did not increase the rate of major bleeding or transfusions in patients with cancer undergoing surgery; their use was associated with decreased risk for VTE.  
medscape.com
about 4 years ago
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'Triple Therapy' Raises Bleed Risk After PCI for MI: Study

Regardless of P2Y12 receptor inhibitor used, the risk of bleeding complications went up by adding an oral anticoagulant to dual-antiplatelet therapy—maybe more so with one particular antiplatelet.  
medscape.com
about 4 years ago
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GI Bleeding in Patients With AF on Rivaroxaban or Warfarin

GI bleeding is a common complication of oral anticoagulation. How does the incidence of GI bleeding in AF patients taking rivaroxaban compare to those on warfarin?  
medscape.com
about 4 years ago
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Can Inpatient Proton Pump Inhibitors Raise Death Risk? CME/CE

: In this simulation study, routine application of proton pump inhibitors to prevent gastrointestinal tract bleeding among medical inpatients was linked with higher risks for hospital mortality.  
medscape.org
about 4 years ago
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Radial-Access Rare in STEMI Post-Lytic 'Rescue' PCI: NCDR

"Transradial rates are still surprisingly low for a population that you would expect to be at high risk for bleeding," say researchers, who attribute the finding to the "risk-treatment" paradox.  
medscape.com
about 4 years ago