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Alcoholic Hepatitis

This is a very common cause of liver injury. It is caused by excessive alcohol intake. Typically there will be steatosis of the liver. In this pathological change, fat globules begin to accumulate in the cytoplasm of liver cells. this can be pretty harmless, and as a result, is not very specific for predicting if the liver will develop cirrhosis. - free medical student revision notes
almost 7 years ago

Hepatitis B/ Chronic Hepatitis/Serum Hepatitis

• In the family Hepadnaviridae; common name: Hepadnavirus • Known as the smallest DNA virus • Double stranded, circular 42 nm DNA genome;Virion also called Dan…  
almost 7 years ago

Response from Hepatitis C Trust, BASL, BIA, BVHG, BSG, and BHIVA to article asking whether widespread screening for hepatitis C is justified

Koretz and colleagues argue that hepatitis C virus (HCV) screening should be delayed.1 We disagree. HCV transmission was common in the 1960s-80s, and because mortality occurs 30-40 years after infection deaths will rise exponentially over the next decade.2 Delaying effective intervention will have a massive impact. The authors argue that because a community study showed an increase in liver and non-liver mortality most infected people will not die from HCV. Infection can cause or exacerbate renal disease, diabetes, and dyslipidaemia and treatment reduces all cause mortality,3 indicating that both liver and non-liver related deaths are caused by …
almost 6 years ago

Could these results indicate hepatitis?

Could these results indicate hepatitis? White cell count - 22 x 109/L (4-11) C-reactive protein (CRP)- 256 mg/L (<10) Serum alkaline phosphatase - 178U/L (45-105) Serum gamma glutamyl tranferase - 437 U/L (<50) Serum aspartate aminotransferase - 297 U/L (1-31) Serum total bilirubin - 10 µmol/L (1-22) Serum amylase - 2018 U/L (60-180) Serum urea - 6.7 mmol/L (2.5-7.5) Serum creatinine - 98 µmol/l (60-110) Raised white cell count and CRP indicate inflammation and liver-function tests are abnormal (except bilirubin). Would abnormal ALP, AST & GGT indicate hepatitis or does a normal bilirubin indicate normal breakdown of red cells & therefore normal liver function? Though my real problem here is I know that these are liver function tests, but not WHY they are liver function tests (and therefore how else abnormal results could occur...) Cheers.  
b d
over 8 years ago

What is the most likely diagnosis?

Female patient 19 years old came to outpatient clinic with goitre, type 1 DM since one month, and hepatosplenomegally in ultrasound. Hepatitis markers are negative. What is the most likely diagnosis? That's the case which I was asked today!  
Mohammad Hamouda
about 8 years ago
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Consultantitis - Part 1

consultant NOUN a person who provides expert advice professionally: he acted as campaign consultant to the president [OFTEN AS MODIFIER] British a hospital doctor of senior rank within a specific field: a consultant paediatrician -itis SUFFIX forming names of inflammatory diseases: cystitis, hepatitis (Origin - from Greek feminine form of adjectives ending in -it?s (combined with nosos 'disease' implied) ) You may not be surprised to hear that the way in which I recently heard the term 'consultantitis' used cannot be understood to mean 'inflammation of the senior hospital doctor'. Although, I wish it was. Professionalism, compassion, transparency, teamwork and communication - all terms that appear to be used with an increasing regularity within the NHS. These are concepts that are not merely taught but preached to medical students today. Why? Well it is nit merely the work of a heavily publicised inquiry into a foundation trust, neither is it the upshot of the medical profession's own Voldemort - he who must not be named (except I will name him - Harold Shipman). Is it then an attempt to heal the wounds within our national health service from within? I hope so. Yet, there are countless more 'isms' and other terms being muttered under the breath of healthcare professionals all over the country. 'Consultantitis' is one that fills me with sadness for one reason in particular: it suggests that those at the top are at the core of some of the problems. Ponder over that for a while, I intend to explain myself further in my next blog post. To be continued****.  
Chantal Cox-George
about 7 years ago

Anticonvulsants for cocaine dependence | Cochrane

Cocaine is an illicit drug available as a powder for intranasal or intravenous use or smoked as crack. Short- and long-term use of this drug results in the spread of infectious diseases (for example, AIDS, hepatitis, tuberculosis), crime, violence and prenatal drug exposure. Cocaine dependence is associated with medical and psychosocial complications and is a major public health problem. No proven pharmacological treatment for cocaine dependence is known. Antidepressant, anticonvulsant and dopaminergic medications have all been studied. The present review looked at the efficacy and safety of anticonvulsant drugs for treating cocaine dependence, both as a class and individually.
almost 6 years ago