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Estrogen, Insulin Sensitivity, and Diabetes: Is Timing Everything?

Dr JoAnn Manson discusses the data evaluating the effect of estrogen replacement on insulin sensitivity and diabetes, finding that the timing of estrogen initiation may modify this relationship.  
medscape.com
over 4 years ago
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The safety of incretin based drug treatments for type 2 diabetes

The incretin based drugs (dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon-like peptide-1 receptor agonists) are one of several options for glucose lowering in people with type 2 diabetes who are already taking (or unable to take) metformin.1 As with other antidiabetic drugs, the long term safety of these drugs remains unclear. Studies by Azoulay and colleagues (doi:10.1136/bmj.i581) and Li and colleagues (doi:10.1136/bmj.i610) in this issue provide updated evidence about incretin based treatments and the risk of pancreatic cancer and heart failure.2 3  
feeds.bmj.com
over 4 years ago
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Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study

Objective To determine whether the use of incretin based drugs compared with sulfonylureas is associated with an increased risk of incident pancreatic cancer in people with type 2 diabetes.  
feeds.bmj.com
over 4 years ago
Www.bmj
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Testosterone may improve sexual function and mood in older men with low levels

Treatment with testosterone improved sexual function and mood in men aged over 65 with low levels of the hormone but had no effect on physical functioning or vitality, a randomised trial has shown.1 But researchers warned that larger studies are needed to adequately assess any potential risks from this therapy.  
feeds.bmj.com
over 4 years ago
Www.bmj
0
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Testosterone may improve sexual function and mood in older men with low levels

Treatment with testosterone improved sexual function and mood in men aged over 65 with low levels of the hormone but had no effect on physical functioning or vitality, a randomised trial has shown.1 But researchers warned that larger studies are needed to adequately assess any potential risks from this therapy.  
feeds.bmj.com
over 4 years ago
Www.bmj
0
0

The safety of incretin based drug treatments for type 2 diabetes

The incretin based drugs (dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon-like peptide-1 receptor agonists) are one of several options for glucose lowering in people with type 2 diabetes who are already taking (or unable to take) metformin.1 As with other antidiabetic drugs, the long term safety of these drugs remains unclear. Studies by Azoulay and colleagues (doi:10.1136/bmj.i581) and Li and colleagues (doi:10.1136/bmj.i610) in this issue provide updated evidence about incretin based treatments and the risk of pancreatic cancer and heart failure.2 3  
feeds.bmj.com
over 4 years ago
Preview
0
0

Testosterone may improve sexual function and mood in older men with low levels

Treatment with testosterone improved sexual function and mood in men aged over 65 with low levels of the hormone but had no effect on physical functioning or vitality, a randomised trial has shown.1 But researchers warned that larger studies are needed to adequately assess any potential risks from this therapy.  
feeds.bmj.com
over 4 years ago
Preview
0
2

Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study

Objective To determine whether the use of incretin based drugs compared with sulfonylureas is associated with an increased risk of incident pancreatic cancer in people with type 2 diabetes.  
feeds.bmj.com
over 4 years ago
Preview
0
0

The safety of incretin based drug treatments for type 2 diabetes

The incretin based drugs (dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon-like peptide-1 receptor agonists) are one of several options for glucose lowering in people with type 2 diabetes who are already taking (or unable to take) metformin.1 As with other antidiabetic drugs, the long term safety of these drugs remains unclear. Studies by Azoulay and colleagues (doi:10.1136/bmj.i581) and Li and colleagues (doi:10.1136/bmj.i610) in this issue provide updated evidence about incretin based treatments and the risk of pancreatic cancer and heart failure.2 3  
feeds.bmj.com
over 4 years ago
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Classification of hormones mindmap

I made this mind map when I was in my second year of medicine I hope everyone get a benefit from it :)  
Mohammed AlShammari
over 4 years ago
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0

Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study

Objective To determine whether the use of incretin based drugs compared with sulfonylureas is associated with an increased risk of incident pancreatic cancer in people with type 2 diabetes.  
feeds.bmj.com
over 4 years ago
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ACOG Supports Vaginal Estrogen in Breast Cancer Survivors

The Committee on Gynecologic Practice of the American College of Obstetricians and Gynecologists has issued an opinion in support of vaginal estrogen in breast cancer survivors.  
medscape.com
over 4 years ago
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New Data Inform but Don't Confirm Incretin Diabetes Drugs Safety

Two new studies find that incretin-based drugs for the treatment of type 2 diabetes don't cause pancreatic cancer in the short term, but some may raise the risk of heart failure.  
medscape.com
over 4 years ago
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Managing Menopause: Are the WHI Results Being Misunderstood?

Dr JoAnn Manson clarifies misunderstandings about the use of hormone therapy for postmenopausal women.  
medscape.com
over 4 years ago
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Infertile Men Have Higher Risk of Diabetes, Osteoporosis

Low sperm counts may indicate future risk for diabetes and osteoporosis, and affected men should have reproductive hormone levels checked, according to a new study.  
medscape.com
over 4 years ago
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2

GLP-1 and Hormonal Secretion in Posttransplant Diabetes

The incretin hormone glucagon-like peptide 1 (GLP-1) appears to correct the abnormal secretion of insulin and glucagon in posttransplantation diabetes (PTDM), researchers from Norway and Denmark report.  
medscape.com
over 4 years ago
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Efficacy and Safety of Corticosteroids in Pneumonia

Although widely used, is there an actual benefit to using a short course of systemic corticosteroids in community-acquired pneumonia?  
medscape.com
over 4 years ago
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Acupuncture May Ease Hot Flashes in Women With Breast Cancer

Acupuncture may help ease hot flashes in women with breast cancer who often can't take traditional hormone treatments, according to a new study from Italy.  
medscape.com
over 4 years ago
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Endocrine Society Advises Against Compounded Hormone Use

A new scientific statement details the science of hormonal compounds for treating menopausal symptoms, sexual dysfunction, and thyroid conditions, emphasizing the superiority of FDA-approved products.  
medscape.com
over 4 years ago
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ELITE Provides Reassurance About Estrogen in Early Menopause

The just-published ELITE trial suggests that coronary risk should not be a justification to deny hormone therapy to appropriate candidates in early menopause.  
medscape.com
over 4 years ago