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Hyperglycemia

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Critical Care

Elevated blood glucose levels during intensive care unit (ICU) stay, so-called stress hyperglycaemia (SH), is a common finding. Its relation with a future diabetes risk is unclear. Our objective was to determine the incidence of disturbed glucose metabolism (DGM) post ICU admission and to identify predictors for future diabetes risk with a focus on stress hyperglycaemia.  
ccforum.com
over 4 years ago
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Rachel Clark and colleagues reply to Eleanor Barry and colleagues

Eleanor Barry and colleagues’ editorial relays their concerns about the NHS Diabetes Prevention Programme (DPP).1 Key concerns are dealt with here. The NHS DPP will offer people already identified as being at high risk of developing type 2 diabetes an opportunity to lower their risk through provision of an evidence based behavioural intervention. By failing to implement such a programme, people with known non-diabetic hyperglycaemia are deprived of consistent and evidence based support that would empower them to reduce their risk of type 2 diabetes, questioning our commitment to the public’s health and wellbeing.  
feeds.bmj.com
over 4 years ago
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Hyperglycemia and Catheter-Associated Bloodstream Infections

Should blood glucose be controlled before placing central lines in criticall ill children?  
medscape.com
over 4 years ago
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Hyperglycaemia in acute coronary syndromes: management | Guidance and guidelines | NICE

This guideline will shortly be checked to see if it needs updating, please register as a stakeholder to be informed about the decision.  
nice.org.uk
over 4 years ago
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Pharmacist-Led Teams Improve Postsurgical Glycemic Control

Inpatient pharmacy-led team was associated with postsurgical improvements in glycemic control and healthcare utilization among patients with diabetes or hyperglycemia at 2 years.  
medscape.com
over 4 years ago
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Critical Care

Patients admitted to the intensive care unit often develop hyperglycaemia, but the underlying mechanisms have not been fully described. The incretin effect is reduced in patients with type 2 diabetes. Type 2 diabetes and critical illness have phenotypical similarities, such as hyperglycaemia, insulin resistance and systemic inflammation. Previous studies have shown beneficial effects of exogenous glucagon-like peptide (GLP)-1 on glycaemia in critically ill patients, a phenomenon also seen in patients with type 2 diabetes. In this study, we hypothesised that the incretin effect, which is mediated by the incretin hormones GLP-1 and glucose-dependent insulinotropic peptide (GIP), is impaired in critically ill patients.  
ccforum.com
over 4 years ago
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Diabetes a Big Risk Factor for Surgical Site Infections

Patients with diabetes have over a 50% increased risk of surgical site infection and this remained the case even after controlling for hyperglycemia. The highest risk was seen for cardiac surgery.  
medscape.com
over 4 years ago
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Acute Hyperglycemia Affects Remote Ischemic Perconditioning

Gain a better understanding of how acute hyperglycemia impacts the cardioprotective effects of remote ischemic preconditioning.  
medscape.com
over 4 years ago
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Post-Cardiac-Surgery Hyperglycemia: Not One Size Fits All

This hypothesis-generating study suggests that "insulin-treated diabetic patients may benefit from a glucose-control approach that is more lenient than that applied to nondiabetic patients," say researchers.  
medscape.com
over 4 years ago
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Selecting the right drug treatment for adults with type 2 diabetes

Clinicians prescribe one or more antihyperglycaemic drugs to prevent and treat symptomatic hyperglycaemia and to lower haemoglobin A1c levels in people with type 2 diabetes. The available agents differ in their efficacy and safety and in how they burden patients in terms of dosing, side effects, and cost. Comparative estimates across these outcomes are generally lacking, limiting the ability of patients and clinicians to make informed decisions.  
feeds.bmj.com
about 4 years ago
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Selecting the right drug treatment for adults with type 2 diabetes

Clinicians prescribe one or more antihyperglycaemic drugs to prevent and treat symptomatic hyperglycaemia and to lower haemoglobin A1c levels in people with type 2 diabetes. The available agents differ in their efficacy and safety and in how they burden patients in terms of dosing, side effects, and cost. Comparative estimates across these outcomes are generally lacking, limiting the ability of patients and clinicians to make informed decisions.  
feeds.bmj.com
about 4 years ago
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Diabetes treatments and risk of amputation, blindness, severe kidney failure, hyperglycaemia, and hypoglycaemia: open cohort study in primary care

Objective To assess the risks of amputation, blindness, severe kidney failure, hyperglycaemia, and hypoglycaemia in patients with type 2 diabetes associated with prescribed diabetes drugs, particularly newer agents including gliptins or glitazones (thiazolidinediones).  
feeds.bmj.com
about 4 years ago
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Selecting the right drug treatment for adults with type 2 diabetes

Clinicians prescribe one or more antihyperglycaemic drugs to prevent and treat symptomatic hyperglycaemia and to lower haemoglobin A1c levels in people with type 2 diabetes. The available agents differ in their efficacy and safety and in how they burden patients in terms of dosing, side effects, and cost. Comparative estimates across these outcomes are generally lacking, limiting the ability of patients and clinicians to make informed decisions.  
feeds.bmj.com
about 4 years ago
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Diabetes treatments and risk of amputation, blindness, severe kidney failure, hyperglycaemia, and hypoglycaemia: open cohort study in primary care

Objective To assess the risks of amputation, blindness, severe kidney failure, hyperglycaemia, and hypoglycaemia in patients with type 2 diabetes associated with prescribed diabetes drugs, particularly newer agents including gliptins or glitazones (thiazolidinediones).  
feeds.bmj.com
about 4 years ago
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Australian paediatric guidelines already acknowledge hypoglycaemia as an indicator of good diabetes care

Rodriguez-Gutierrez and colleagues emphasise that diabetes guidelines in the UK and US, except for those from the US Department of Veterans Affairs, focus on hyperglycaemia as a quality measure at the expense of hypoglycaemia and re-iterate the adverse effects of hypoglycaemia on health.1  
feeds.bmj.com
about 4 years ago
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Vitamin D and Stress Hyperglycaemia in the Critically Ill

Vitamin D deficiency is common in critically ill patients with stress-induced hyperglycemia. Can supplementation improve outcomes?  
medscape.com
almost 4 years ago