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Question on step 4 asthma management in adults.

First thing you do is increase the inhaled steroid dose, but then you can consider adding a theophylline, leukotriene receptor antagonist or B2 agonist. Is there any preference over which one to choose when, or do you literally pick one and see if it suits the patient, if not pick another?  
Conrad Hayes
almost 8 years ago
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Consequences of a mutation on RAG proteins

Looks at consequences of a mutation in RAG proteins  
Thomas Lemon
almost 8 years ago
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Emergency Protocol for Bronchial Asthma

provides details of Management of asthma exacerbations in adults  
Kamal Eldirawi
almost 8 years ago
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Hypersensitivity reactions

The pathophysiology of different hypersensitivity reactions.  
Klara Morsley
almost 8 years ago
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Aspergillus and Human Health

Many may be familiar with aspergillosis as the infecting agent in acute cases where the patient is severely immunocompromised - but there is more to this fungus' repertoire. There are rare cases where the patient's immune system is overwhelmed by a large inhalation of spores e.g. after gardening, but these are insignificant in terms of total numbers effected. The following are far more common:- Aspergillus and other fungi are increasingly identified as the active agent in sinusitis - if you have cases that don't respond to antibiotics this is worth thinking about. Chronic pulmonary aspergillosis (CPA & aspergilloma) is an infection of immunocompetent people, causing respiratory difficulty, coughing and haemoptysis. The UK NHS has a specialist centre for these patients In Manchester (National Aspergillosis Centre (NAC)). NAC has particular expertise and extensive facilities for the diagnosis of CPA, ABPA, SAFS and use of systemic antifungal drugs. Allergic infection (Allergic Bronchopulmonary Aspergillosis - ABPA and chronic sinusitis) is thought to be heavily underdiagnosed and undertreated. ABPA is particularly common in Asthma, Cystic Fibrosis patients and those with bronchiectasis. There is estimated to be 25 000 cases in the UK alone. Many (50%) of the most severe asthma cases are sensitive to fungi (SAFS) - in particular Aspergillus. These tend to be the most unstable cases that don't respond to antibiotics and several studies have been published that show giving an antifungal helps reduce the use of steroids for these patients. Last but not least - Tuberculosis is on the rise in the UK and the rest of the world. It is estimated that 2% of cases progress to CPA and should be treated using an antifungal - this is usually not done until considerable time has passed and much damage has been done. In total it is estimated that many millions of people across the world suffer from aspergillus - ABPA - 5 million, Tb - 400 000 per year and Asthma (SAFS - 1 - 4 million cases in EU & US). Sinusitis cases may number many tens of millions worldwide. So - the next time you assume aspergillus infections and aspergillosis are rare and confined to those who are profoundly immunocompromised - think again! If you have a patient who has increasingly severe respiratory symptoms, doesn't respond to multiple courses of antibiotics then give aspergillus a thought. Browse around these articles for further information Aspergillus Website Treatment Section. NB For a broader look at the prevalence of fungal diseases worldwide the new charity Leading International Fungal Education (LIFE) website is worth looking at.  
Graham Atherton
almost 8 years ago
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Asthma

Case history with pathophysiology, diagnosis and treatment. Patient details changed to preserve anonymity.  
Anne Parfitt-Rogers
about 8 years ago
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Why is MgSO4 used in acute asthma management?

The anesthetists loves magnesium. But when I asked of the mechanism from A&E consultants, I got replies that it is wonder drug, or not well understood. Anyone got a more comprehensive answer than that?  
Stuart Chan
about 8 years ago
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childhood asthma

slide presentation of childhood asthma, covering about epidemiology, pathology, presentation, investigation and management and prognosis.  
malek ahmad
about 8 years ago
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Is it true that the number of people with allergies is increasing?

I heard that more people are being diagnosed with alleges, such as nut allergies. Is there any really understanding of why this is?  
Becky Archer
about 8 years ago
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Food allergy

A short, 16-slide presentation on the topic of immunologically-mediated food allergies, both IgE and call mediated types. Covers the epidemiology, aetiology, pathophysiology, presentation, history/investigations and management.  
Phil Byass
about 8 years ago
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Asthma: nebuliser and inhaler use

This video - produced by students at Oxford University Medical School in conjunction with the faculty - demonstrates how to use a nebuliser and explain correct inhaler technique to a patient. It is part of a series of videos covering Respiratory Medicine skills.  
Hussam Rostom
over 8 years ago
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Respiratory Distress & Status asthmaticus in Paediatrics

A detailed presentation about Respiratory Distress & Status asthmaticus in Paediatric patients  
DR. AMY
over 8 years ago
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Asthma

This video tutorial covers the history, examination, differential diagnosis, investigations and management of asthma.  
Podmedics
over 9 years ago
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Allergies and anaphylaxis

This session was designed to teach first year medical students about allergies and the basic medical management of anaphylaxis. The session was student led with a tutor in the audience to help provoke discussion and encourage students to participate. The session utilised an interactive smart-board with touch-screen function in order to get students involved in learning. Although the information is not overly complex it is a good introduction to the topic and promoted student involvement as well as group interaction and teamwork.  
Ben Green
over 9 years ago
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The handy guide to anaemia

The handy guide comprises a series of 5 short videos explaining different aspects of anaemia. The videos show my hands displaying cardboard cut outs of pictures I drew to explain the story of anaemia, an idea which I thought might make the information more memorable for students.  
kate mccormick
over 9 years ago
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Immunology & Schistosomiasis (Bilharzia)

An interactive learning resource that explores the life cycle of the Schistosoma mansoni parasite and how it exploits the human immune system in order to survive. All links are back up and running. Please let me know if you experience any diffuclties. Thank you!  
Daniel Sapier
almost 10 years ago
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Infection summary

Summary of infection , covering immunology, infectious diseases and treatments  
Philip Welsby
almost 10 years ago
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MTPH1 2009 | Case 2 presented by Gracy Joshua, MD

ResearchToPractice.com/MTPH109 – Case 2 from the practice of Gracy Joshua, MD presented to Drs Gregory and Orlowski, moderated by Neil Love, MD. A woman in her early sixties with follicular lymphoma and a prior history of severe allergic reaction to rituximab experienced a complete remission with bendamustine/rituximab after disease progression on prior treatments with COP, fludarabine and single-agent rituximab. Produced by Research To Practice.  
Dr Neil Love
over 10 years ago
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Immunology Poster Presentation to AMEE 09

 
Raquel Tarazona
almost 11 years ago
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Urticaria

Image of urticaria Image taken from www.wikipedia.org  
Jon Philtron
about 12 years ago