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2
35

Comparative effectiveness of long term drug treatment strategies to prevent asthma exacerbations: network meta-analysis

Objective To determine the comparative effectiveness and safety of current maintenance strategies in preventing exacerbations of asthma.  
bmj.com
over 5 years ago
Www.bmj
1
20

Maintenance treatment for adults with chronic asthma

Which treatment for asthma is most likely to reduce the risk of exacerbations in adults? In a linked paper, Loymans and colleagues (doi:10.1136/bmj.g3009) seek to address this question using network meta-analysis.1 The authors identified and compared 16 different treatment approaches, using evidence from randomised trials of at least 24 weeks’ duration. The primary outcome was severe exacerbations (leading to admission to hospital, a visit to the emergency department, or a course of oral steroids).  
bmj.com
over 5 years ago
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1
16

Clinical trials: units of randomisation

Researchers evaluated the efficacy of a short course of oral prednisolone for acute asthma in children of school age. A randomised double blind placebo controlled crossover trial study design was used. The intervention was parent initiated treatment with the corticosteroid prednisolone (1 mg/kg/day) or placebo when an episode of acute asthma occurred. For each episode, treatment with prednisolone or placebo was chosen at random. Participants were 230 children aged 5-12 years with a history of recurrent episodes of acute asthma. Each child could contribute a maximum of eight episodes of acute asthma to the data collection over a three year study period.1  
bmj.com
over 5 years ago
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1
13

Clinical trials: units of randomisation

Researchers evaluated the efficacy of a short course of oral prednisolone for acute asthma in children of school age. A randomised double blind placebo controlled crossover trial study design was used. The intervention was parent initiated treatment with the corticosteroid prednisolone (1 mg/kg/day) or placebo when an episode of acute asthma occurred. For each episode, treatment with prednisolone or placebo was chosen at random. Participants were 230 children aged 5-12 years with a history of recurrent episodes of acute asthma. Each child could contribute a maximum of eight episodes of acute asthma to the data collection over a three year study period.1  
bmj.com
over 5 years ago
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5
112

Asthma death: Mother 'shattered' after ambulance delay - BBC News

A mother describes the pain of losing her daughter to asthma, when an ambulance went to the wrong address.  
BBC News
over 5 years ago
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1
25

Non-eosinophilic asthma

Stream Non-eosinophilic asthma by BMJ talk medicine from desktop or your mobile device  
SoundCloud
over 5 years ago
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1
34

Internal medicine on Instagram: “Erythema nodosum Painful erythematous nodules of erythema nodosum are often found in a symmetric distribution on the legs. The nodules can…”

“Erythema nodosum Painful erythematous nodules of erythema nodosum are often found in a symmetric distribution on the legs. The nodules can also appear to…”  
Instagram
over 5 years ago
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1
6

Immunology Map V Cell Mediated Immunity

More Anatomy Lessons : https://www.youtube.com/user/AnatomyProfStudent Anatomy video Anatomy vagin Anatomy penis Anatomy prof students Anatomy videos medical...  
YouTube
almost 5 years ago
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1
15

Immunology Adaptive Immune System

More Anatomy Lessons : https://www.youtube.com/user/AnatomyProfStudent Anatomy video Anatomy vagin Anatomy penis Anatomy prof students Anatomy videos medical...  
YouTube
almost 5 years ago
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2
18

Immunology - Toll Like Receptors Overview

https://www.facebook.com/ArmandoHasudungan Support me: http://www.patreon.com/armando Instagram: http://instagram.com/armandohasudungan Twitter: https://twit...  
YouTube
almost 5 years ago
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1
14

Immunology - MHC II Processing

https://www.facebook.com/ArmandoHasudungan Support me: http://www.patreon.com/armando Instagram: http://instagram.com/armandohasudungan Twitter: https://twit...  
YouTube
almost 5 years ago
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1
19

Immunology - MHC I Processing

https://www.facebook.com/ArmandoHasudungan Support me: http://www.patreon.com/armando Instagram: http://instagram.com/armandohasudungan Twitter: https://twit...  
YouTube
almost 5 years ago
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1
21

Update on basic and clinical aspects of eosinophilic oesophagitis

Stream Update on basic and clinical aspects of eosinophilic oesophagitis by BMJ talk medicine from desktop or your mobile device  
SoundCloud
almost 5 years ago
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1
17

The genomic origins of asthma

Stream The genomic origins of asthma by BMJ talk medicine from desktop or your mobile device  
SoundCloud
almost 5 years ago
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0
15

Dilated vein

UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, Nephrology and Hypertension, Neurology, Obstetrics, Gynecology, and Women's Health, Oncology, Pediatrics, Pulmonary, Critical Care, Sleep Medicine, Rheumatology, Surgery, and more.  
uptodate.com
almost 5 years ago
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1
45

Rheumatology Secrets

The new and expanded second edition of this popular volume covers the common and uncommon rheumatic disorders encountered in practice, discussed on rounds, and found on exams. Each chapter reviews basic immunology and pathophysiology, important disease manifestations, and practical management issues. This edition features a new section on Pain Management. Mnemonics, lists, tables, illustrations and the engaging format of The Secrets Series® make this text enjoyable and useful.  
Google Books
over 4 years ago
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1
51

Asthma: pathogenesis and novel drugs for treatment

Asthma affects almost 20 million people in the United States and more than 300 million people worldwide. Of these, 10-15% have severe asthma, which is refractory to commonly available drugs. New drugs are needed because those that are currently available cannot control symptoms and exacerbations in all patients and can cause adverse reactions. In the past 10 years, there have been substantial advances in the understanding of asthma genetics, airway biology, and immune cell signaling. These advances have led to the development of small molecule therapeutics and biologic agents that may improve asthma care in the future. Several new classes of asthma drugs—including ultra long acting β agonists and modulators of the interleukin 4 (IL-4), IL-5, IL-13, and IL-17 pathways—have been evaluated in randomized controlled trials. Other new drug classes—including dissociated corticosteroids, CXC chemokine receptor 2 antagonists, toll-like receptor 9 agonists, and tyrosine kinase inhibitors—remain in earlier phases of development. Despite some preliminary efficacy data, there is insufficient evidence to make strong recommendations about the use of these newer agents. Future research on the clinical efficacy of these biologic agents, the effect of newer agents on severe asthma in pediatric patients, and the biology of non-eosinophilic and corticosteroid resistant asthma is needed to reduce the morbidity of asthma worldwide.  
bmj.com
over 4 years ago
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4
423

Asthma Pathophysiology

https://www.facebook.com/ArmandoHasudungan Support me: http://www.patreon.com/armando Instagram: http://instagram.com/armandohasudungan Twitter: https://twit...  
YouTube
over 4 years ago
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1
3

Immunology - Toll Like Receptors Overview

https://www.facebook.com/ArmandoHasudungan Support me: http://www.patreon.com/armando Instagram: http://instagram.com/armandohasudungan Twitter: https://twit...  
YouTube
over 4 years ago