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How big a threat are superbugs? - BBC News

The Victoria Derbyshire programme looks at the battle against infections that are resistant to drugs.  
bbc.co.uk
over 3 years ago
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Increase in deaths from antibiotic resistant infections may limit rising longevity, report warns

Around 50 000 deaths a year in Europe and the United States are due to antibiotic resistant infections, warns a report on antimicrobial resistance that predicts that the problem may outweigh increases in longevity over the next decade.1  
feeds.bmj.com
over 3 years ago
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Clean cut surgery

Infection of the surgical site, a major threat for all postoperative patients and a leading cause of hospital acquired infections, is a particular problem in low resource settings, where rates are double those reported in Europe and the United States.1 With no global approach to instilling best practice, it’s a problem that causes unnecessary morbidity and mortality and strains hospital systems and budgets.  
feeds.bmj.com
over 3 years ago
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Behaviours Immediately Following a New STI Diagnosis

Abstinence? Partner notification? This study assesses patients' sexual behaviours during the period immediately following a new diagnosis of a curable sexually transmitted infection.  
medscape.com
over 3 years ago
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Late mortality after sepsis

A new series of definitions of sepsis1 along with simple guidance for early diagnosis has recently been published, and a NICE guideline is due shortly.2 Sepsis is an extreme manifestation of the body responding to a severe infection—in part adaptive and protective, but potentially maladaptive and life threatening. Naturally, perhaps, the focus has been on early diagnosis and management. This is not always performed well, as highlighted by a 2015 report from the UK National Confidential Enquiry into Patient Outcome and Death.3 In a linked paper, Prescott and colleagues (doi:10.1136/bmj.i2375) report that patients who survive an episode of sepsis have a significant excess risk of mortality for a prolonged period of time.4 In the past, staff working in intensive care units discharged patients to the rest of the hospital with a feeling of a job well done; somehow that part of the patient’s journey had come to an end and recovery was about to begin. Since then numerous publications have challenged this optimistic assumption. For substantial numbers of patients, leaving the intensive care unit does not represent the end of something, rather it represents the start of something else, often not anticipated by them or understood by others. Many studies have described the difficulties sustained by patients and of course their families. Such difficulties include loss of muscle mass and strength,5 cognitive dysfunction, anxiety and depression,6 and post-traumatic stress.7 Along with this come challenges, both medical and financial, for those who become informal caregivers.8 9 In the UK this has been addressed, at least in ambition, with the publication of NICE guidelines for rehabilitation after critical illness.10  
feeds.bmj.com
over 3 years ago
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Certain Skin and Tissue Lesions Point to Zika Virus Infection

Certain dermatological features coupled with other symptoms signal a likely diagnosis of Zika virus infection, researchers report.  
medscape.com
over 3 years ago
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US warns against use of fluoroquinolones for uncomplicated infections

The risk of the serious side effects associated with fluoroquinolone antibiotics outweighs their benefits for the treatment of sinusitis, bronchitis, and uncomplicated urinary tract infections, the US Food and Drug Administration (FDA) said in an advisory issued …  
feeds.bmj.com
over 3 years ago
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Rosuvastatin vs Placebo in Sepsis-Associated ARDS

How do patients with sepsis and acute respiratory distress syndrome fare one year after treatment with rosuvastatin?  
medscape.com
over 3 years ago
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Late mortality after sepsis: propensity matched cohort study

Objectives To determine whether late mortality after sepsis is driven predominantly by pre-existing comorbid disease or is the result of sepsis itself.  
feeds.bmj.com
over 3 years ago
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US warns against use of fluoroquinolones for uncomplicated infections

The risk of the serious side effects associated with fluoroquinolone antibiotics outweighs their benefits for the treatment of sinusitis, bronchitis, and uncomplicated urinary tract infections, the US Food and Drug Administration (FDA) said in an advisory issued …  
feeds.bmj.com
over 3 years ago
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Schistosoma haematobium Infection That Mimics Bladder Cancer

This patient's history of gross hematuria led to a suspicion of bladder cancer, but cystoscopic testing revealed a more unusual cause.  
medscape.com
over 3 years ago
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C difficile-Related Reactive Arthritis Misdiagnosed in Kids

As C difficile infection rates rise in the US children, prompt recognition and treatment of associated arthritis are needed.  
medscape.com
over 3 years ago
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New (and Cheaper) HCV Therapy: Option for HIV Coinfection?

A recently approved once-daily combination product for HCV offers a new option for coinfected patients. Dr Paul Sax compares it, and its price, with existing therapy.  
medscape.com
over 3 years ago
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US warns against use of fluoroquinolones for uncomplicated infections

The risk of the serious side effects associated with fluoroquinolone antibiotics outweighs their benefits for the treatment of sinusitis, bronchitis, and uncomplicated urinary tract infections, the US Food and Drug Administration (FDA) said in an advisory issued …  
feeds.bmj.com
over 3 years ago
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US warns against use of fluoroquinolones for uncomplicated infections

Register for a free trial to thebmj.com to receive unlimited access to all content on thebmj.com for 14 days. Sign up for a free trial  
feeds.bmj.com
over 3 years ago
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Chronic HCV Infection: A New Cardiovascular Risk Factor?

Are patients with chronic hepatitis C at an increased risk for developing cardiovascular disease? This new study explores the connection.  
medscape.com
over 3 years ago
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Bundle Decreases Infections in High-Risk Surgeries

An evidence-based bundle significantly reduced the overall surgical site infection rate among patients who underwent high-risk gynecologic cancer surgeries, a new study has found.  
medscape.com
over 3 years ago
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Identification and Clinical Management of Persons with Chronic Hepatitis C Virus Infection — Cherokee Nation, 2012–2015 | MMWR

The Morbidity and Mortality Weekly Report (MMWR) Series is prepared by the Centers for Disease Control and Prevention (CDC).  
cdc.gov
over 3 years ago