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Stem cell trial in unborn babies will start next year: A clinical trial that will involve injecting fetal stem cells into fetuses identified with brittle bone disease is to begin in January. The trial, led by Sweden’s Karolinska Institute and Great Ormond Street Hospital in London, will use stem cells from terminated pregnancies that develop into healthy bone, cartilage, and muscle. Brittle bone disease affects around one in 25 000 births and can be fatal. It can cause multiple fractures and other problems.  
feeds.bmj.com
almost 4 years ago
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Breathing training before surgery for reducing lung complications after surgery in adults undergoing heart and major abdominal surgery | Cochrane

Despite advances regarding patient care in the last few decades, breathing complications as a result of lung injury after surgery such as pneumonia are the leading cause of sickness and death in adults undergoing heart and major abdominal surgery. Training of breathing muscles using a small device at home before surgery seems to make breathing easier and helps strengthen muscles of respiration after surgery. This training may help reduce breathing complications after surgery and may lead to improved patient care and overall health care cost savings for the public health system. We wanted to establish whether training of breathing muscles before surgery can reduce the risk of lung complications and to identify who in particular might benefit from such training.  
cochrane.org
almost 4 years ago
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Paralyzed Patient Uses Brain-Computer Interface to Walk

A computer translating brain waves and sending signals to stimulate leg muscles has allowed a patient who was paralyzed after a spinal cord injury to walk.  
medscape.com
almost 4 years ago
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Anatomy Of The Tibialis Posterior Muscle - Everything You Need To Know - Dr. Nabil Ebraheim

Educational video describing the anatomy of the tibialis posterior muscle. Become a friend on facebook: http://www.facebook.com/drebraheim Follow me on twitt...  
youtube.com
almost 4 years ago
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Alendronate may help maintain muscle mass too

Alendronate may have a beneficial effect on muscle mass in addition to its well known positive effect on bone mass, hint preliminary findings from Japan.  
medscape.com
almost 4 years ago
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Pentoxifylline for intermittent claudication | Cochrane

Atherosclerosis, or hardening of the arteries, results in narrowing and blockage of the arteries and can reduce the blood supply to the legs, causing peripheral arterial disease. Intermittent claudication (IC) is a cramp-like pain felt in the leg muscles that is brought on by walking and is relieved by standing still or resting. Pentoxifylline is a drug that is used to relieve IC while improving people's walking capacity. It decreases blood viscosity and improves red blood cell flexibility, promoting microcirculatory blood flow and increasing oxygen in the tissues. This review looked at all available evidence from randomised controlled trials on the efficiency of pentoxifylline for treatment of IC.  
cochrane.org
almost 4 years ago
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Should Welsh rugby team ditch the big freeze? - BBC News

The Welsh Rugby team might want to ditch cryotherapy sessions ahead of their match against Fiji on Thursday, say medical experts who have evaluated this deep freeze treatment for tired muscles.  
bbc.co.uk
almost 4 years ago
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Completely Paralyzed Man Walks with Help of a Brain Computer Interface, Muscle Stimulators |

In California, a paralyzed man took a small step that will be great for mankind. In a world's first, researchers at the University of California, Irvine ar  
medgadget.com
almost 4 years ago
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Resistance Training Alters Mitochondrial Function in Muscle

In what ways does resistance exercise impact mitochondrial respiratory function within the skeletal muscle?  
medscape.com
almost 4 years ago
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'Bigorexia': Muscle dysmorphia 'now affects one in 10 gym-going men' - BBC News

Muscle dysmorphia, also known as "bigorexia", may now be affecting one in 10 men who visit gyms in the UK, according to the Body Dysmorphic Disorder Foundation.  
bbc.co.uk
almost 4 years ago
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Muscle dysmorphia: One in 10 men in gyms believed to have 'bigorexia'

Exclusive music news, big interviews, entertainment, social media trends and video from the news people at BBC Radio 1 and 1Xtra.  
bbc.co.uk
almost 4 years ago
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Sizing Up Tumors and Delineating Their Boundaries Using Vibrating Nanoparticles |

Mechanical resonance frequencies in rat and human tissue samples. (a) Rat muscle and (b) rat lung tissue. (c) Human adipose tissue and tumor. The red and b  
medgadget.com
almost 4 years ago
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Branched-chain amino acids improve symptoms of hepatic encephalopathy | Cochrane

Hepatic encephalopathy is a brain dysfunction associated with liver disease. Cirrhosis, which is a condition where scar tissue (fibrosis) replaces the normal liver tissue, is the most common cause of hepatic encephalopathy. The severity of the symptoms range from minor signs to coma. The minor changes are known as minimal hepatic encephalopathy. Overt hepatic encephalopathy refers to the more severe stages with clinically apparent manifestations such as changes in the level of consciousness or neuropsychiatric abnormalities. Many people with cirrhosis lack amino acids, which are building blocks of proteins. The amino acids with a side-chain (a branch) are known as branched-chain amino acids (BCAA). The BCAA play an important part of the generation muscles and of the signalling chemicals in the brain. These effects may benefit people with hepatic encephalopathy.  
cochrane.org
about 4 years ago
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Surgical fixation methods for treating tibial plateau fractures (breaks in the top end of the shin bone) in adults | Cochrane

What is the medical problem? Fractures of the tibial plateau are injuries affecting the top end of the tibia (shin bone), which forms the lower bone surface in the knee joint. These fractures are often associated with a large amount of damage to the skin and muscle and may cause voids or defects in the bone.  
cochrane.org
about 4 years ago
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Lab Case 71 – Interpretation

Potassium plays a major role in regulating the skeletal muscle blood flow; an increased potassium concentration in the muscle during muscle activity causes vasodilatation, which increases the regional blood flow. In state of hypokalemia, this increase is hampered causing relative ischemia in the active muscle consecutively leading to muscle cramps, and in a severely depleted state may cause muscle necrosis and rhabdomyolysis. In addition to hypoperfusion, hypokalemia-induced impairment in muscle metabolism also may contribute to muscle dysfunction.  
emergucate.com
about 4 years ago
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The Extraocular Muscles - Study Resource

Described are extraocular muscles and how they move the human eye.  
tedmontgomery.com
about 4 years ago
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Rotator Cuff | Flashcard Anatomy

Rotator cuff muscles anatomy flashcard. Check out the 3D app at http://AnatomyLearning.com. More videos available on http://AnatomyZone.com. Use this brief f...  
youtube.com
about 4 years ago
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Neurotransmitter Receptors Alter Postsynaptic Membrane Permeability - Neuroscience - NCBI Bookshelf

In 1907, the British physiologist John N. Langley introduced the concept of receptor molecules to explain the specific and potent actions of certain chemicals on muscle and nerve cells. Much subsequent work has shown that receptor molecules do indeed account for the ability of neurotransmitters, hormones, and drugs to alter the functional properties of neurons. While it has been clear since Langley's day that receptors are important for synaptic transmission, their identity and detailed mechanism of action remained a mystery until quite recently. It is now known that neurotransmitter receptors are proteins embedded in the plasma membrane of postsynaptic cells. Domains of receptor molecules that extend into the synaptic cleft bind neurotransmitters that are released into this space by the presynaptic neuron. The binding of neurotransmitters, either directly or indirectly, causes ion channels in the postsynaptic membrane to open or close (Figure 7.1). Typically, the resulting ion fluxes change the membrane potential of the postsynaptic cell, thus mediating the transfer of information across the synapse. Figure 7.1Receptors that mediate the postsynaptic actions of neurotransmitters have two functions. First, specific binding sites on the extracellular side of receptors allow these proteins to detect the presence of neurotransmitters in the synaptic cleft. Second, transmitter-bound receptors alter the ionic permeability of the postsynaptic membrane by virtue of being coupled, directly or indirectly, to ion channels in the postsynaptic membrane. Opening or closing these channels as a result of transmitter binding allows ionic currents to flow, thus changing the postsynaptic membrane potential.  
ncbi.nlm.nih.gov
about 4 years ago
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Beta2-agonist drugs for treating cough or a clinical diagnosis of acute bronchitis | Cochrane

Acute bronchitis is a chest infection, with cough and sometimes sputum production, chest pain and fever. People affected feel unwell and for those who do not have asthma or chronic lung disease there is no clear treatment. Viruses cause most cases of bronchitis, so antibiotics usually do not help. Beta2-agonists (such as albuterol or salbutamol) are drugs that relieve asthma by relaxing muscles that cause narrowing in the passages to the lungs. They are sometimes used to relieve the cough in acute bronchitis, even in people who do not have asthma.  
cochrane.org
about 4 years ago
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Hand Muscles | Flashcard Anatomy

Hand muscles anatomy flashcard. Check out the 3D app at http://AnatomyLearning.com. More videos available on http://AnatomyZone.com. Use this brief flashcard...  
youtube.com
about 4 years ago