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Is Long-Term NSAID Use Harmful to Athletes?

Do nonsteroidal anti-inflammatory drugs inhibit muscle repair and regeneration in athletes? The answer remains elusive, but experts still caution against long-term daily use for inflammation relief.  
medscape.com
almost 5 years ago
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1

Comparison of two muscle relaxants, rocuronium and succinylcholine, to facilitate rapid sequence induction intubation | Cochrane

Which drug (rocuronium or succinylcholine) is better at providing excellent conditions to quickly insert breathing tubes into participants of all ages for elective and emergency situations?  
cochrane.org
almost 5 years ago
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To investigate if using ultrasound to look at anal muscles after childbirth reduces women's suffering from gas, liquid or solid stool leakage | Cochrane

Many women have a tear to the skin between the vagina and anus (the perineum) following childbirth. These tears can sometimes involve the muscles that control the function of the anus, and women can suffer for the rest of their lives with difficulty controlling gas, liquid and solid stool. Evidence shows that by properly repairing these tears, complications can be reduced. The muscles can often be difficult to see with the naked eye due to a number of factors including reduced lighting, swelling of the tissues and poor pain relief.  
cochrane.org
almost 5 years ago
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Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary incontinence in women | Cochrane

Involuntary leakage of urine (urinary incontinence) affects women of all ages, particularly older women who live in residential care, such as nursing homes. Some women leak urine during exercise or when they cough or sneeze (stress urinary incontinence). This may occur as a result of weakness of the pelvic floor muscles, which may be a result of factors such as damage during childbirth. Other women leak urine before going to the toilet when there is a sudden and compelling need to pass urine (urgency urinary incontinence). This may be caused by involuntary contraction of the bladder muscle. Mixed urinary incontinence is the combination of both stress and urgency urinary incontinence. Pelvic floor muscle training is a supervised treatment that involves muscle-clenching exercises to strengthen the pelvic floor muscles. It is a common treatment used by women to stop urine leakage. Other treatments are also available, which can be used either alone, or in combination with pelvic floor muscle training.  
cochrane.org
almost 5 years ago
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Intrathecal baclofen for treating spasticity in children with cerebral palsy | Cochrane

Spasticity, which is an increase in muscle tone, is the most common difficulty with movement seen in children with cerebral palsy. Baclofen is a medication which acts on receptors in the brain and spinal cord to reduce abnormal muscle tone. It has been used as an oral medication for many years. The disadvantages of oral administration are that only a small amount of the medication crosses the blood-brain barrier before it can exert an effect, and that the dose is limited by the unwanted effect of excessive sedation. The administration of baclofen into the fluid surrounding the spinal cord overcomes these problems. This treatment is called intrathecal baclofen therapy and it is administered via a pump placed under the skin connected to a catheter which enters the membranes covering the spinal cord to deliver the baclofen directly into the fluid surrounding the spinal cord and brain.  
cochrane.org
almost 5 years ago
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12

Proximal Muscle Rehabilitation for Patellofemoral Pain

How do these rehabilitation protocols for patellofemoral pain compare in terms of pain reduction and improved function?  
medscape.com
almost 5 years ago
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8

Carnegie Mellon's Prosthetic Leg Control Software Modeled on Natural Reflexes |

Researchers at Carnegie Mellon University have been studying the way that humans and other animals use their muscles in order to better control powered pro  
medgadget.com
almost 5 years ago
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Prenatal treatments for babies with congenital diaphragmatic hernia | Cochrane

A congenital diaphragmatic hernia (CDH) is a hole in the diaphragm, the muscle that helps with breathing and separates the chest and abdomen. This defect can allow the liver and bowel to move to the chest cavity and interfere with lung development, affecting lung and heart function in newborn babies. At birth, respiratory insufficiency and pulmonary hypertension contribute to poor outcomes. About one in every 3000 babies may be affected and the problem can be diagnosed during a routine mid-pregnancy ultrasound at around 20 weeks. For babies born with a CDH, surgery in early life is necessary, but even with new surgical techniques there can be a poor outlook and many long-term medical problems. Treatments are now possible in pregnancy. Interventions described to date include maternal antenatal corticosteroid administration and prenatal tracheal occlusion to improve lung growth and maturity by obstruction of the fetal trachea. This increases airway pressure by preventing secreted lung fluid from leaving the lungs resulting in growth and expansion of the lungs. There are potential side effects and complications for the mother with this procedure as the uterus and amniotic sac are entered in order to gain access to the unborn baby.  
cochrane.org
almost 5 years ago
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Neurotoxins: Concepts in Cosmetic Use on the Face and Neck

This article describes techniques for the cosmetic application of botulinum toxin in the targeted treatment of muscles of the lower face.  
medscape.com
almost 5 years ago
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FDA Panel Backs Reslizumab for Adults With Severe Asthma

The advisory committee ruled that evidence wasn't strong enough for recommending the drug for children aged 12 to 17 years, citing small numbers in studies; concerns include risk for anaphylaxis and muscle toxicity.  
medscape.com
almost 5 years ago
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Muscle and Bone Atrophy Follow Facial Transplantation

Significant muscle and bone atrophy occur in the first three years after facial transplantation, resulting in an appearance transformation that resembles accelerated aging, according to a new report.  
medscape.com
almost 5 years ago
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Motor Control Exercises Help Ease Lower Back Pain

This type of exercise, which strengthens muscles supporting the spine, reduces pain but is not superior to other exercise interventions.  
medscape.com
over 4 years ago
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Quadriceps Performance Under Foot Dorsal Extension

This study examines EMG activity changes of the m. quadriceps femoris muscle with and without dorsal foot extension.  
medscape.com
over 4 years ago
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VIVY Diathermy Pain Relief Device |

Soon a new wearable may be coming to market that uses a technology called diathermy to help alleviate muscle and joint pain, as well as to help with healin  
medgadget.com
over 4 years ago
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Shaping Up for Surgery: Study Shows Muscle Power Pays Off

Completing a 30-minute home-exercise program daily for 10 days before a radical cystectomy can significantly improve muscle strength, new research shows.  
medscape.com
over 4 years ago
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A patient with muscle weakness

A 29 year old woman presented with symptoms of muscle weakness and difficulty swallowing. Physical examination showed swollen upper eyelids with a violaceous eruption (fig 1⇓). The dorsal side of her fingers was covered with an erythematous eruption. She also had bilateral symmetric purple discoloration of her skin in the area of the sternocleidomastoid muscle (fig 2⇓) and difficulty raising her arms above her head. A full blood cell count was normal. Creatinine kinase was raised at 1577 U/L (reference range 30-135).  
feeds.bmj.com
over 4 years ago
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A patient with muscle weakness

A 29 year old woman presented with symptoms of muscle weakness and difficulty swallowing. Physical examination showed swollen upper eyelids with a violaceous eruption (fig 1⇓). The dorsal side of her fingers was covered with an erythematous eruption. She also had bilateral symmetric purple discoloration of her skin in the area of the sternocleidomastoid muscle (fig 2⇓) and difficulty raising her arms above her head. A full blood cell count was normal. Creatinine kinase was raised at 1577 U/L (reference range 30-135).  
feeds.bmj.com
over 4 years ago
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7

A patient with muscle weakness

A 29 year old woman presented with symptoms of muscle weakness and difficulty swallowing. Physical examination showed swollen upper eyelids with a violaceous eruption (fig 1⇓). The dorsal side of her fingers was covered with an erythematous eruption. She also had bilateral symmetric purple discoloration of her skin in the area of the sternocleidomastoid muscle (fig 2⇓) and difficulty raising her arms above her head. A full blood cell count was normal. Creatinine kinase was raised at 1577 U/L (reference range 30-135).  
feeds.bmj.com
over 4 years ago
Preview
0
7

A patient with muscle weakness

A 29 year old woman presented with symptoms of muscle weakness and difficulty swallowing. Physical examination showed swollen upper eyelids with a violaceous eruption (fig 1⇓). The dorsal side of her fingers was covered with an erythematous eruption. She also had bilateral symmetric purple discoloration of her skin in the area of the sternocleidomastoid muscle (fig 2⇓) and difficulty raising her arms above her head. A full blood cell count was normal. Creatinine kinase was raised at 1577 U/L (reference range 30-135).  
feeds.bmj.com
over 4 years ago
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It’s time to regulate the use of whole body electrical stimulation

Transcutaneous electrical stimulation (ES) of human nerves and muscles has long been used as a non-pharmacological treatment for pain relief,1 and for rehabilitation after disuse. Whole body ES has recently emerged as an alternative form of physical exercise for improving fitness and health in healthy people. Despite limited scientific evidence on the safety and effectiveness of this form of exercise, several ES company sponsored fitness centres have recently been opened in different countries worldwide,2 making this technology easily accessible to the general population.  
feeds.bmj.com
over 4 years ago