New to Meducation?
Sign up
Already signed up? Log In

Category

Preview
0
0

Gene Mutation Linked to Persistent ADHD

A polymorphism in a gene for a subunit in the NMDA receptor may predict persistent attention-deficit/hyperactivity disorder, new findings show.  
medscape.com
over 4 years ago
Preview
0
0

A Potential Therapeutic Target in ALS and Dementia

Researchers have identified mutations that may be a key to understanding and treating some forms of neurodegeneration.  
medscape.com
over 4 years ago
Preview
0
3

Fatal Infantile Mitochondrial Disease With OPA1 Mutation

The authors establish a causal link between a pathogenic homozygous OPA1 mutation and human disease, emphasizing the vital role played by OPA1 in mitochondrial biogenesis.  
medscape.com
over 4 years ago
Preview
0
14

Mom Pushes for Molecular Autopsy After Son's Sudden Death

A woman who fought for answers after her son died unexpectedly discovered a genetic mutation that might explain generations of sudden deaths in her family.  
medscape.com
over 4 years ago
Preview
0
2

BRCA Mutation Testing Increasing in Younger Women

BRCA1 and BRCA2 genetic testing is on the increase, but so is bilateral mastectomy, even among women without increased genetic risk for breast cancer.  
medscape.com
over 4 years ago
Preview
0
0

VPS11 Mutation in Ashkenazi-Jewish Patients

The authors identify the loci of a mutation resulting in a syndrome of developmental delay, acquired microcephaly and hypomyelination in Ashkenazi-Jews.  
medscape.com
over 4 years ago
Preview
0
0

Comparing First-Line TKI Options for EGFR-Positive NSCLC

Are there clinically significant differences among first-line EGFR TKI options for EGFR mutation-positive NSCLC?  
medscape.com
over 4 years ago
Preview
0
0

Age at First Breast Cancer Predicts Contralateral BC Risk

Younger age at the time of diagnosis of primary breast cancer is associated with a higher 10-year risk of contralateral breast cancer (CBC) in women who are carriers of BRCA1/2 mutations, a new study confirms.  
medscape.com
over 4 years ago
Preview
0
0

A Gene-Based Approach to Epilepsy Therapy

If patients are willing to pay for it, they can now access precision medicine wherein their specific mutation is tested in a laboratory to find the best therapy.  
medscape.com
over 4 years ago
Preview
0
0

Most Cancers Are Not Due to 'Bad Luck'

A new study challenges earlier findings that suggested that many cancers are the result of random mutations rather than external factors.  
medscape.com
over 4 years ago
Preview
0
1

Inherited Mutations Common in Therapy-Related Leukemia

Survivors of breast cancer who develop therapy-related leukemia (TRL) commonly have inherited mutations in cancer susceptibility genes, researchers have found.  
medscape.com
almost 5 years ago
Preview
0
0

Resistance Mutations: Next in ER+ Metastatic Breast Cancer?

Estrogen receptor mutations can be easily detected in the plasma of patients with metastatic breast cancer and may hold the key to targeted treatments for women with endocrine-resistant disease, according to new analysis of patients in the BOLERO-2 trial.  
medscape.com
almost 5 years ago
Preview
0
2

Midostaurin in AML: First Targeted Agent Improves Survival

The targeted agent was added onto chemotherapy in patients with acute myeloid leukemia and the FLT3 mutation (found in about 30% of cases).  
medscape.com
almost 5 years ago
Preview
0
0

BRIP1, BARD1, PALB2, and NBN Mutations in Ovarian Cancer

Do these rare protein-truncating gene variants increase risk of ovarian cancer? The latest research is right here.  
medscape.com
almost 5 years ago
Preview
0
6

Why Some Children Get Cancer: Germline Mutations Found

An analysis of genomes and exomes of children and adolescents has identified commonly mutated genes in the germline that may explain pediatric cancers.  
medscape.com
almost 5 years ago
Ht 151113 tagrisso pill 800x600
0
1

FDA OKs Osimertinib for Specific Non-Small-Cell Lung Cancers

A new drug is available for patients with non-small-cell lung cancer (NSCLC) who progress on epidermal growth-factor receptor inhibitors and who have a specific related mutation.  
medscape.com
almost 5 years ago
Preview
0
0

NEJM Study: Mutations ID'd That Lead to Melanoma

An analysis of gene mutations showed that the path to melanoma varied according to precursor lesion, that 'high-risk' lesions had genetic markers, and that UV light played a role throughout.  
medscape.com
almost 5 years ago
Preview
0
0

FDA Approves Cotellic as Part of Melanoma Combination

The MEK inhibitor cobimetinib (Cotellic, Roche) works with already-approved vemurafenib for the treatment of advanced melanoma that is BRAF mutation-positive.  
medscape.com
almost 5 years ago
Preview
0
0

'Milestone' prostate cancer drug - BBC News

The first drug that targets precise genetic mutations in prostate cancer has been shown to be effective in a "milestone" trial by UK scientists.  
bbc.co.uk
almost 5 years ago
Preview
0
0

Altered Brain Connectivity in Kids at Risk for Huntington's

Having the genetic mutation for Huntington's disease appears to affect brain development decades before onset of symptoms.  
medscape.com
almost 5 years ago