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Evidence points to fallopian-tube origins of ovarian cancers

A new surgical approach that removes the fallopian tubes while sparing the ovaries may provide premenopausal women at high risk for ovarian cancer, particularly those with BRCA1/2 mutations...  
medicalnewstoday.com
about 6 years ago
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World-first cancer drugs could work in larger group of patients

A pioneering class of drugs that target cancers with mutations in the BRCA breast cancer genes could also work against tumours with another type of genetic fault, a new study suggests.  
medicalnewstoday.com
about 6 years ago
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Lives at risk as women are too scared to find out if they carry the 'faulty' BRCA cancer gene mutation

According to new research by leading research charity, Ovarian Cancer Action, a quarter of women say they would choose NOT to be tested for the BRCA gene mutation (which can lead to both...  
medicalnewstoday.com
about 6 years ago
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Mitochondria are altered in human cell model of Parkinson's disease

Buck Institute research provides tool for testing of potential therapeuticsBased on research in fruit flies, it has long been suspected that the most common mutation...  
medicalnewstoday.com
about 6 years ago
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Gene in high-altitude cattle disease sheds light on human lung disease

Vanderbilt University researchers have found a genetic mutation that causes pulmonary hypertension in cattle grazed at high altitude, and which leads to a life-threatening condition called...  
medicalnewstoday.com
about 6 years ago
Nci 150417 test tubes cancer tumor 800x600
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EGFR Testing Not Done in 25% of Lung Cancer Patients

Not all patients with advanced NSCLC undergo testing for the EGFR mutation, and for some patients who do undergo testing, therapy is initiated before the results are received.  
medscape.com
about 6 years ago
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Detection of BRAF Mutations Through Cell Transfer Technique

Is cell transfer technique a reliable method for isolating tumor cells for ancillary BRAF mutation analysis?  
medscape.com
about 6 years ago
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Exercise for older mouse mothers lowers risk of heart defects in babies

In people, a baby's risk of congenital heart defects is associated with the age of the mother. Risk goes up with increasing age. Newborn mice predisposed to heart defects because of genetic mutations show the same age association. A new study demonstrates that older mouse mothers reduce this risk for their offspring to that of younger mouse mothers through exercise alone, according to researchers at Washington University School of Medicine in St. Louis.  
eurekalert.org
about 6 years ago
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Genetics - Genetic testing and counselling - NHS Choices

Genetic testing can be used to find out whether a person is carrying a specific genetic mutation (altered gene) that causes a particular medical condition.  
nhs.uk
almost 6 years ago
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Mutations in Brain Metastases Raise Hope for Therapy

More than half of brain metastases from primary tumors have unique genetic mutations that may make them targets for effective therapy, say US researchers.  
medscape.com
over 5 years ago