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Www.bmj
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A rash in a patient with neutropenia

A 72 year old man with relapsed acute myeloid leukaemia developed a rash seven days after starting a combined chemotherapy regimen (fludarabine, cytarabine, granulocyte colony stimulating factor, and idarubicin). He first noticed a painful lesion on his left forefoot, and over the next seven days he developed similar lesions on the left lower limb (fig 1⇓), right thigh, and face. He was referred for a dermatological opinion on day 14.  
bmj.com
over 4 years ago
Www.bmj
0
18

A rash in a patient with neutropenia

A 72 year old man with relapsed acute myeloid leukaemia developed a rash seven days after starting a combined chemotherapy regimen (fludarabine, cytarabine, granulocyte colony stimulating factor, and idarubicin). He first noticed a painful lesion on his left forefoot, and over the next seven days he developed similar lesions on the left lower limb (fig 1⇓), right thigh, and face. He was referred for a dermatological opinion on day 14.  
feeds.bmj.com
over 4 years ago
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0
5

Quick medicine: cyclic neutropenia

Prepare for USMLE,UK,CANADIAN,AUSTRALIAN, NURSING & OTHER MEDICAL BOARD examinations around the globe with us.Understand the basics, concepts and how to answ...  
youtube.com
over 4 years ago
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0
0

Quick medicine: cyclic neutropenia - YouTube

Prepare for USMLE,UK,CANADIAN,AUSTRALIAN, NURSING & OTHER MEDICAL BOARD examinations around the globe with us.Understand the basics, concepts and how to answ...  
youtube.com
over 4 years ago
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0
5

Transfusions of white blood cells called granulocytes for preventing infections in people who lack functioning granulocytes | Cochrane

Review question We evaluated the evidence about whether granulocyte transfusions given to prevent infection are safe and decrease the risk of infection. Our target population was people with neutropenia (a very low count of a type of white blood cell (neutrophil), or white blood cells that did not function properly (neutrophil dysfunction).  
cochrane.org
over 4 years ago
Www.bmj
0
6

Many drugs used for rheumatic disease cause neutropenia

We agree with Hay and colleagues that, although neutropenia worries clinicians, it is often an unimportant finding and rarely requires treatment.1  
feeds.bmj.com
over 4 years ago
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1
16

A study of the use of clozapine in old age psychiatry.

The aim of this study was to review the use of clozapine in a Sydney area old age psychiatry service. Data were extracted from case files of all people who were treated in a health area's old age psychiatry units with clozapine during a 15-year period. Additional details were obtained from clinicians who provided ongoing care after discharge from the hospital. Note was made of psychiatric diagnoses, length of time taking clozapine, dosage, side effects and outcome. Sixteen patients aged over 65 years commenced or continued taking clozapine while inpatients of the service. Of the 13 patients who had a history of schizophrenia or schizoaffective disorder, four patients (all female) developed neutropenia and therefore clozapine was stopped. In one case, neutropenia was first diagnosed 6 years after commencing the medication. Two women died; the nine other women, and one of the deceased, stopped taking clozapine, usually because of side effects. The mean daily dose at cessation was 236 mg. All five men were still taking clozapine (mean 260 mg daily) when followed at a mean age of 72 years, having taken it for an average of 10 years. This case review adds to evidence of the risk of neutropenia when older people are prescribed clozapine.  
ncbi.nlm.nih.gov
over 4 years ago
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3

Clozapine: FDA Acts to Address Neutropenia Risk

The FDA clarifies and enhances prescribing information, changes neutropenia monitoring practices, and launches a new shared REMS program.  
medscape.com
about 4 years ago
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0

Stem Cell Transplantation in Severe Congenital Neutropenia: An Analysis From the European Society for Blood and Marrow Transplantation: Abstract and Introduction

Abstract and Introduction: Matched donor hematopoietic stem cell transplantation has a good outcome in severe congenital neutropenia, but careful patient selection is needed because of high transplant-related mortality.  
medscape.org
about 4 years ago