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105

Acetaminophen Pathway (therapeutic doses), Pharmacokinetics

Acetaminophen (N-acetyl-p-aminophenol, APAP, or paracetamol, PARA) is widely used for its analgesic and antipyretic properties in many over-the-counter formulations in both adults and children [Articles:21054454, 23719833]. APAP can be synthesized in the body through O-dealkylation of the prodrug phenacetin, a pain-killer that was withdrawn from the market due to nephrotoxicity and carcinogenesis [Article:7002186]. At the therapeutic adult dose of 1-2 g/day, oral APAP is indicated for fever and mild to moderate acute pain conditions [Article:23719833]. Administration of acetaminophen via intravenous route has become increasingly widespread and has been used as a safe and effective antipyretic and analgesic agent [Article:25521845]. Maximum recommended therapeutic dose of APAP is 4 g/day in adults and 50-75 mg/kg/day in children. Consumption of a single dose greater than 7 g in an adult and 150 mg/kg in a child is considered potentially toxic to the liver and kidneys due to the highly active metabolite N-acetyl-p-benzoquinone imine (NAPQI)[Article:22998987].  
pharmgkb.org
over 4 years ago
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110

Core Clinical Cases in Obstetrics and Gynaecology Third Edition

You've read your textbook and your course notes. Now you need to apply your knowledge to real life clinical situations. The problem-solving approach of Core Clinical Cases guides you to think of the patient as a whole, rather than as a sequence of unconnected symptoms. With its emphasis on everyday practice strongly linked to underlying theory, the series integrates your knowledge with the realities of managing clinical problems, and provides a basis for developing sound analytical and confident decision-making skills. The core areas of undergraduate study are covered in a logical sequence of learning activities; the same questions are asked of each clinical case, followed by detailed explanatory answers. OSCE counselling cases, with related questions and answers, also feature in each section. Key concepts and important information are highlighted, and the reader-friendly layout reflects exactly the type of question you will encounter, making these volumes the perfect revision aid for all types of case-based examination. The Obstetrics and Gynaecology volume, fully revised and updated in this third edition, focuses on the following topics: * Early pregnancy problems * Pregnancy dating and fetal growth * Late pregnancy problems * Labour * Medical disorders of pregnancy * Puerperium * Abnormal uterine bleeding * Amenorrhoea and menopause * Incontinence and prolapse * Neoplasia * Discharge and pain* Infertility * Fertility control Volumes in the Core Clinical Cases series remain absolutely invaluable in the run up to clinical, written or OSCE examinations, and ideal course companions for all undergraduate medical students at various stages in their clinical training.  
books.google.co.uk
over 4 years ago
Preview
2
76

Core Clinical Cases in Obstetrics and Gynaecology Third Edition

You've read your textbook and your course notes. Now you need to apply your knowledge to real life clinical situations. The problem-solving approach of Core Clinical Cases guides you to think of the patient as a whole, rather than as a sequence of unconnected symptoms. With its emphasis on everyday practice strongly linked to underlying theory, the series integrates your knowledge with the realities of managing clinical problems, and provides a basis for developing sound analytical and confident decision-making skills. The core areas of undergraduate study are covered in a logical sequence of learning activities; the same questions are asked of each clinical case, followed by detailed explanatory answers. OSCE counselling cases, with related questions and answers, also feature in each section. Key concepts and important information are highlighted, and the reader-friendly layout reflects exactly the type of question you will encounter, making these volumes the perfect revision aid for all types of case-based examination. The Obstetrics and Gynaecology volume, fully revised and updated in this third edition, focuses on the following topics: * Early pregnancy problems * Pregnancy dating and fetal growth * Late pregnancy problems * Labour * Medical disorders of pregnancy * Puerperium * Abnormal uterine bleeding * Amenorrhoea and menopause * Incontinence and prolapse * Neoplasia * Discharge and pain* Infertility * Fertility control Volumes in the Core Clinical Cases series remain absolutely invaluable in the run up to clinical, written or OSCE examinations, and ideal course companions for all undergraduate medical students at various stages in their clinical training.  
books.google.co.uk
over 4 years ago
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26

MSK Lesion Videos

Upper Limb  Adhesive Capsulitis Carpal Tunnel Syndrome De Quervain's Tenosynovitis Lateral Epicondylitis Medial Epicondylitis Osteoarthritis of the Thumb Carpometacarpal Joint Supraspinatus Tendonitis Lower Limb Achilles Tendonitis Anserine Bursitis Chronic Ankle Sprain Greater Trochanteric Pain Syndrome Patellofemoral Pain Plantar Fasciitis  
rheumatologytoolbox.com
about 4 years ago
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6

What is The Calmare Pain Therapy treatment? -

Chronic pain is at an epidemic level in the United States. Many types of chronic pain are very difficult to diagnosis and treat, as it can be a genetic code mutation (hereditary), the result of another underlying cause, or progressive or chronic Peripheral Neuropathy. A new neurotheraphy has been helping Peripheral Neuropathy sufferers across the globe alleviate advanced cases of pain by a non-invasive FDA cleared electrostimulation therapy: The Calmare Pain Therapy treatment.  
calmareaz.com
about 4 years ago
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36

Is there a cure for Complex Regional Pain Syndrome?

Every now or then, many of us experiences the term “pain”. Although folks look for alleviation utilizing whatever is accessible, as often as possible individuals find that nothing truly lives up to expectations successfully. Pain management pros commit their vocations to making sense of approaches to offer help.  
innovativetechnology.kinja.com
about 4 years ago
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8

Pediatric Rheumatology

Anterior knee pain is common in children and adolescents. Evaluation and management is challenging and requires a thorough history and physical exam, and understanding of the pediatric skeleton. This article will review common causes of chronic anterior knee pain in the pediatric population with a focus on patellofemoral pain.  
ped-rheum.com
almost 4 years ago
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15

Critical limb ischaemia in peripheral vascular disease: intravenous iloprost | key-points-from-the-evidence | Advice | NICE

A Cochrane review of low quality studies of prostanoids in people with critical limb ischaemia unsuitable for surgery found that compared with placebo, intravenous iloprost statistically significantly reduced major amputations, improved rest-pain relief, and improved ulcer healing. The benefit of intravenous iloprost on total amputations (major plus minor) was not statistically significant. In a randomised controlled trial (RCT) in people undergoing femorodistal bypass surgery for critical limb ischaemia, perioperative intravenous and intra-graft iloprost did not improve graft patency or clinical status, or reduce amputations at 1‑year follow-up compared with placebo. Adverse events were more common with intravenous iloprost than with placebo and included pain at the infusion site, headache, flushing, nausea and vomiting, and hypotension.  
nice.org.uk
almost 4 years ago
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19

How to Avoid Neck Pain from Texting

Research reveals that the distinct neck bend seen in texting teens and adults is causing a new overuse syndrome known as "text neck." Learn what can be done to avoid it.  
spine-health.com
almost 4 years ago
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26

Complex Regional Pain Syndrome - Causes, Treatment & Therapies - Gold Canyon AZ

The Complex regional pain syndrome (CRPS) is an unceasing pain condition that often affects one of the limbs (that can be arms, legs, hands, or feet), generally after an injury or trauma to that particular limb. Complex regional pain syndrome is believed to be caused due to damage, or malfunctioning of the peripheral and central nervous systems. The central nervous system encompasses the brain and spinal cord; whereas the peripheral nervous system includes the nerve signaling from the brain and the spinal cord to the other parts of the body. The Complex Regional Pain Syndrome is exemplified by prolonged or a chronic pain and mild or dramatic changes in the color of the skin, temperature or even swelling in the affecting area.  
calmareaz.com
almost 4 years ago
Beeaebd1818da1ee117791f917e152d70c9795619160898634431754
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Spine pain

What Texting Can Do To Your Spine  
Shaan E Elahi
over 3 years ago
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31

Which nerve transmits pain sensation of a fissure in ano?

This video is part of a playlist of short videos which are intended to combine multiple choice questions' answering experience with an improved understanding...  
youtube.com
over 3 years ago
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6

Sciatica ? why ? Animation

Sciatica causes pain that radiates out from the lower back, down the buttocks and into one or both of the legs, right down to the calf. This animation explai...  
youtube.com
over 3 years ago
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56

Exercises for a Healthy Back

Most people will have back pain at some time in their lives. These exercises will show how to stretch out some of the common pain causing muscles.  
youtube.com
over 3 years ago
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50

Arthritis of the Hand

Arthritis can damage the large joints on your hand at the base of the fingers. If other treatments don't relieve your pain, your doctor may advise artificial...  
youtube.com
over 3 years ago
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42

Focus On: Treating Chronic Pain Patients In the Emergency Department

Although the recognition and management of pain in the emergency department has improved over the past decade, undertreatment of pain, including chronic pain, continues to be common.  
American College Of Emergency Medicine
about 9 years ago
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73

PAIN: a four letter word

The management of pain is a key element of the care of all patients-- ICU or not.  Often providers have little understanding of the concepts and medications of pain management. This episode serves as an introduction.   
Jeffrey S. Guy, MD, FACS
about 9 years ago
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39

Listen to the lecture: Injustice and the chronic pain sufferer

<embed type="application/x-shockwave-flash" width="350" height="24" allowfullscreen="true" allowscriptaccess="always" src="http://www.archive.org/flow/flowplayer.commercial-3.0.5.swf" w3c="true" flashvars='config={"key":"#$b6eb72a0f2f1e29f3d4","playlist":[{"url":"http://www.archive.org/download/InjusticeAndTheChronicPainSufferer/InjusticeAndTheChronicPainSufferer.mp3","autoPlay":false}],"clip":{"autoPlay":true},"canvas":{"backgroundColor":"0x000000","backgroundGradient":"none"},"plugins":{"audio":{"url":"http://www.archive.org/flow/flowplayer.audio-3.0.3-dev.swf"},"controls":{"playlist":false,"fullscreen":false,"gloss":"high","backgroundColor":"0x000000","backgroundGradient":"medium","sliderColor":"0x777777","progressColor":"0x777777","timeColor":"0xeeeeee","durationColor":"0x01DAFF","buttonColor":"0x333333","buttonOverColor":"0x505050"}},"contextMenu":[{"Listen+to+InjusticeAndTheChronicPainSufferer+at+archive.org":"function()"},"-","Flowplayer 3.0.5"]}'> </embed><br /><br />Lecture given by Dr Joanna McParland of Glasgow Caledonian University to the West of Scotland Pain Group on Wednesday 24th March 2010. Dr McParland discusses beliefs about justice and fairness and how they impact on the person with chronic pain.<div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/13562045-963312561037419203?l=wspain.blogspot.com' alt='' /></div>  
West of Scotland Pain Group lectures
about 9 years ago
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143

Prof. Irene Tracey on fMRI and pain

Always on the lookout for interesting pain-related podcasts, we are delighted to bring you a discussion from the <a href="http://podcasts.ox.ac.uk/">University of Oxford</a> with Professor Irene Tracey.<br /><br /><a href="http://media.podcasts.ox.ac.uk/oucs/oxonian_interviews/tracey_interview.mp3">Download Irene Tracey on FMRI and Pain</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/13562045-5354393485471227433?l=wspain.blogspot.com' alt='' /></div>  
West of Scotland Pain Group lectures
about 9 years ago
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Listen to the lecture: The role of illness perceptions and medicine beliefs in adherence to chronic pain medication

Download an <a href="http://www.archive.org/download/TheRoleOfIllnessPerceptionAndMedicineBeliefsInAdherenceToChronic/TheRoleOfIllnessPerceptionsAndMedicineBeliefsInAdherenceToChronicPainMedication-LeanneRamsayMartinDunbar_64kb.mp3">mp3 file</a> of the lecture or listen to streaming audio:<br /><br /><embed src="http://www.archive.org/flow/FlowPlayerLight.swf" allowfullscreen="true" allowscriptaccess="always" quality="high" bgcolor="ffffff" type="application/x-shockwave-flash" pluginspage="http://www.adobe.com/go/getflashplayer" flashvars="config={&quot;controlBarBackgroundColor&quot;:&quot;0x000000&quot;,&quot;loop&quot;:false,&quot;baseURL&quot;:&quot;http://www.archive.org/download/&quot;,&quot;showVolumeSlider&quot;:true,&quot;controlBarGloss&quot;:&quot;high&quot;,&quot;playList&quot;:[{&quot;url&quot;:&quot;TheRoleOfIllnessPerceptionAndMedicineBeliefsInAdherenceToChronic/TheRoleOfIllnessPerceptionsAndMedicineBeliefsInAdherenceToChronicPainMedication-LeanneRamsayMartinDunbar_64kb.mp3&quot;}],&quot;showPlayListButtons&quot;:true,&quot;usePlayOverlay&quot;:false,&quot;menuItems&quot;:[false,false,false,false,true,true,false],&quot;initialScale&quot;:&quot;scale&quot;,&quot;autoPlay&quot;:false,&quot;autoBuffering&quot;:false,&quot;showMenu&quot;:false,&quot;showMuteVolumeButton&quot;:true,&quot;showFullScreenButton&quot;:false}&amp;" width="350px" height="28px"></embed><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/13562045-1273844229544930067?l=wspain.blogspot.com' alt='' /></div>  
West of Scotland Pain Group lectures
about 9 years ago