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GI Physiology Notes

Hope you enjoy and keep studying hard - MK  
Mehar Kaillon
almost 7 years ago
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Effects of opioid, hypnotic and sedating medications on obstructive sleep apnoea (OSA) in adults with known OSA | Cochrane

Obstructive sleep apnoea (OSA) is a common sleep disorder characterised by intermittent apnoeas (pauses in breathing) leading to dips in oxygen levels in the blood during sleep. Many people with known or unknown (undiagnosed) OSA receive hypnotics, sedatives and opiate/opioid drugs to treat other conditions including pain, anxiety and difficulty sleeping. Opiates/opioids are commonly prescribed to treat pain after major surgery. These drugs might make sleep apnoea worse - increasing the frequency and duration of apnoeas.  
cochrane.org
almost 7 years ago
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25

Critical Care

Patients receiving circulatory support with peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) are at risk of developing differential hypoxia. This phenomenon occurs in patients with concomitant respiratory failure. Poorly oxygenated blood, ejected into the ascending aorta from the left ventricle, competes with retrograde flow from the ECMO circuit, potentially causing myocardial and cerebral ischaemia. In a recent Critical Care article, Hou et al. use an animal model of peripheral VA-ECMO to study the physiology of differential hypoxia. Their findings support a dual circuit hypothesis, and show how different cannulation strategies can disrupt the two circuits. In particular, strategies that increase venous oxygen saturations in the pulmonary artery can have a large effect on oxygenation saturation in the ascending aorta. The authors provide evidence supporting the use of veno-arterial-venous ECMO in patients who require peripheral VA-ECMO but have simultaneous respiratory failure.  
ccforum.com
almost 7 years ago
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5

Association between pulmonary vein orientation and atrial fibrillation-free survival in patients undergoing endoscopic laser balloon ablation

Aims Obtaining optimal pulmonary vein (PV) occlusion with the endoscopic laser balloon ablation system (EAS) can be difficult, hypothetically influenced by PV geometry. The aim of this study was to determine the impact of PV orientation on atrial fibrillation (AF)-free survival after PV isolation (PVI) using the EAS.  
ehjcimaging.oxfordjournals.org
almost 7 years ago
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New study expands on the heart benefits of exercise

Exercise promotes heart health. However, many lifestyle factors cause heart disease, and regular activity may not be enough to prevent heart attacks. A new study in the American Journal of Physiology-Heart and Circulatory Physiology expands on the heart benefits of exercise, investigating whether regular exercise still helps the heart even after a heart attack occurs.  
news-medical.net
almost 7 years ago
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17

Cardiac Tamponade and Miscellaneous Cardiomyopathies with Dr. Brown

Dr. Lorrel Brown returns to discuss tamponade cardiac physiology (including demystifying pulsus pardoxus). She continues to cover the differentiation of cons...  
youtube.com
over 6 years ago
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Effects of 'Catch-Up' Sleep in Men With Sleep Restriction

What are the metabolic implications of playing weekend 'catch up' on sleep lost during the work week?  
medscape.com
over 6 years ago