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Rheumatology

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14

Kit Wynn Parry obituary

Other lives: Distinguished rheumatologist who was a pioneer of rehabilitative medicine  
theguardian.com
over 4 years ago
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22

Complete AC joint dislocation (Grade 3): What’s best management? Bob McCormack (Olympic physician)

Stream Complete AC joint dislocation (Grade 3): What’s best management? Bob McCormack (Olympic physician) by BMJ talk medicine from desktop or your mobile device  
feeds.bmj.com
over 4 years ago
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21

Arthritis Research UK Centre: Putting osteoarthritis in the spotlight

Stream Arthritis Research UK Centre: Putting osteoarthritis in the spotlight by BMJ talk medicine from desktop or your mobile device  
feeds.bmj.com
over 4 years ago
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9

Joint British Societies’ consensus recommendations for the prevention of cardiovascular disease

Stream Joint British Societies’ consensus recommendations for the prevention of cardiovascular disease by BMJ talk medicine from desktop or your mobile device  
feeds.bmj.com
over 4 years ago
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24

Ann Furedi at the FSRH/BASHH joint conference

Stream Ann Furedi at the FSRH/BASHH joint conference by BMJ talk medicine from desktop or your mobile device  
feeds.bmj.com
over 4 years ago
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BNPA 2014: Joint hypermobilty and autonomic hyperactivity

Stream BNPA 2014: Joint hypermobilty and autonomic hyperactivity by BMJ talk medicine from desktop or your mobile device  
feeds.bmj.com
over 4 years ago
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The neurology of Sjögren's syndrome and the rheumatology of peripheral neuropathy and myelitis

Stream The neurology of Sjögren's syndrome and the rheumatology of peripheral neuropathy and myelitis by BMJ talk medicine from desktop or your mobile device  
feeds.bmj.com
over 4 years ago
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8

SGEM#39: Weak in the Knees (Diagnosis of Septic Joint)

Case Scenario: 40yo construction worker presents to the emergency department with a swollen and painful right knee. No history of injury. No significant past medical history. Palpable effusion on examination with no overlying redness or warmth to touch. Any movement of the joint is very painful. He is taking no medications. Vital signs are normal.  
thesgem.com
over 4 years ago
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9

Anti-TNF-alpha drugs for treating ankylosing spondylitis | Cochrane

Researchers looked at trials done up to June 2014 on the effect of anti-TNF drugs (adalimumab (Humira®), etanercept (Enbrel®), golimumab (Simponi®), and infliximab (Remicade®)) on ankylosing spondylitis. They found 21 trials with 3308 participants. Most studies were funded by pharmaceutical companies.  
cochrane.org
over 4 years ago
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Balneotherapy (or spa therapy) for rheumatoid arthritis | Cochrane

We reviewed the evidence on the benefits and harms of balneotherapy (natural mineral waters, gases and mudpacks or spa therapy) in people with rheumatoid arthritis. Balneotherapy is defined as bathing in natural mineral or thermal waters (e.g. mineral baths, sulphur baths, Dead Sea baths), using mudpacks or doing both. Upon searching for all relevant studies up to December 2014, we found nine studies with 579 people. The quality of the evidence is very low mainly because of the low number of participants in the studies and concerns about study designs.  
cochrane.org
over 4 years ago
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10

About HeartScore

The need to estimate total cardiovascular risk in apparently healthy individuals has since 1994 been strongly advocated by the joint recommendations from The European Society of Cardiology, European Society of Hypertension, European Atherosclerosis Society and other societies.  
heartscore.org
over 4 years ago
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8

Redox Reactions Explained - Quick Chemistry Review (Examville)

Redox Reactions Explained - Quick Chemistry Review Join for FREE - Examville.com® - the education marketplace (TM). http://www.Examville.com  
youtube.com
over 4 years ago
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Redox Reactions Explained - Quick Chemistry Review (Examville) - YouTube

Redox Reactions Explained - Quick Chemistry Review Join for FREE - Examville.com® - the education marketplace (TM). http://www.Examville.com  
youtube.com
over 4 years ago
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16

Dr. Marcus Snow, Rheumatology

Get to know Dr. Marcus Snow, rheumatology. For more about Dr. Snow: http://doctors.nebraskamed.com/doctors/marcus-snow  
youtube.com
over 4 years ago
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Dr. Marcus Snow, Rheumatology - YouTube

Get to know Dr. Marcus Snow, rheumatology. For more about Dr. Snow: http://doctors.nebraskamed.com/doctors/marcus-snow  
youtube.com
over 4 years ago
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10

Dr. Michael Feely, Rheumatology

Get to know Dr. Michael Feely, rheumatology. For more information about Dr. Feely: http://doctors.nebraskamed.com/doctors/michael-feely  
youtube.com
over 4 years ago
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Dr. Michael Feely, Rheumatology - YouTube

Get to know Dr. Michael Feely, rheumatology. For more information about Dr. Feely: http://doctors.nebraskamed.com/doctors/michael-feely  
youtube.com
over 4 years ago
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BioMed Notes

Obesity in humans is associated with a region around FTO, a "fat mass and obesity-associated” gene on chromosome 16. Although this is the strongest genetic association, it accounts for only a 1-2% difference in Body Mass Index (BMI) and the mechanism was unknown. Here, the investigators looked at regulator proteins binding to variants DNA sequences within the FTO region, particularly those binding to sites with single nucleotide polymorphisms (SNPs), in 100 healthy Europeans -- 52 subjects were homozygous for 3 risk-variant SNPs (both alleles, all 3 loci) and the remaining 48 were homozygous for the non-risk variants. They found that the change of a T-to-C at one SNP within a risk allele of FTO prevented the binding of the repressor protein ARID5B. For want of this binding site, the repressor is lost. For want of this repressor, the expression of 2 linked genes doubles: IRX3, located about half a million base pairs (~0.5 Mbp) away, and IRX5, ~1 Mbp away. IRX3 repression made mice thinner by “increased energy dissipation without a change in physical activity or appetite”, i.e. not changing eating or exercise but rather elevating ‘metabolism’. The doubled expression of IRX3 led to a 5-fold reduction in mitochondrial thermogenesis and a 7-fold difference in brown/white adipose tissue development.  (Brown fat is brown because it holds more mitochondria, little furnaces that burn fat and produce heat.) The risk alleles are causative, and mediate through IRX3 and IRX5, because mimicking the repression of IRX3 or IRX5 in 8 carriers of the risk alleles, but not 10 carriers of the non-risk allele increased stimulated metabolism (Fig 3D, shown, left panel). And overexpression of IRX3 or IRX5 reduced stimulated metabolism in non-risk allele carriers (because their endogenous genes are repressed) but not in risk allele carriers (Fig 3D, right panel). Figure 3D. Oxygen consumption rate (OCR), basal and stimulated, in cells with risk or non-risk alleles. The take-home messages are that the causative SNP can be kilobases away from the genes that mediate the effect (not a huge surprise) and that small risks might develop from relatively big differences in particular developmental and cell biological pathways (reverse butterfly effect: not small-change-to-big-effect but big effect leads to small change (1-2% BMI)). N Engl J Med. 2015 Sep 3;373(10):895-907. “FTO Obesity Variant Circuitry and Adipocyte Browning in Humans.” Claussnitzer M, Dankel SN, Kim KH, Quon G, Meuleman W, Haugen C, Glunk V, Sousa IS, Beaudry JL, Puviindran V, Abdennur NA, Liu J, Svensson PA, Hsu YH, Drucker DJ, Mellgren G, Hui CC, Hauner H, Kellis M  
biomednotes.blogspot.co.uk
over 4 years ago
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Renin Angiotensin Aldosterone System 2/7 - Best Explanation

Start your Free Trial Now: http://www.DrNajeebLectures.com  
youtube.com
over 4 years ago
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Small Joint Arthrocentesis Video

Tapping a small joint isn't too hard with a little help from our friends. Dr. John Sarwark from Procedures Club discusses proper technique in this awesome video with background music that will bring us back to the 1970s.   
emcurious.com
over 4 years ago