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Rheumatology

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Efficacy and Safety of Tabalumab in Rheumatoid Arthritis

Is tabalumab an effective treatment option for reducing rheumatoid arthritis disease activity?  
medscape.com
almost 5 years ago
Dt 150928 fall risk patient walker 800x600
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Joint Commission Issues Alert on Falls in Hospitals

Falls are common and costly in healthcare settings, and not just among the elderly and frail. The Joint Commission wants more attention paid to fall prevention.  
medscape.com
almost 5 years ago
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Raising the Quality of Rheumatology Management

This review examines how to raise the quality of rheumatology guidelines by reviewing the EULAR management recommendations.  
medscape.com
almost 5 years ago
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Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials

Objective To investigate the efficacy and safety of paracetamol (acetaminophen) in the management of spinal pain and osteoarthritis of the hip or knee.  
feeds.bmj.com
almost 5 years ago
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Psoriatic Arthritis: Phase 3 Data Confirm Secukinumab Efficacy

The FUTURE 1 trial has confirmed that selective inhibition of IL-17A improves signs and symptoms of psoriatic arthritis for 1 year.  
medscape.com
almost 5 years ago
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First Guideline on Ankylosing Spondylitis Issued by ACR

The American College of Rheumatology has issued evidence-based treatment recommendations for ankylosing spondylitis and nonradiographic axial spondyloarthritis.  
medscape.com
almost 5 years ago
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Polymyalgia rheumatica in primary care: managing diagnostic uncertainty

A 78 year old white woman presented with a six week history of bilateral shoulder stiffness and pain. Stiffness was the main symptom—it was so severe that she could not dress herself or brush her hair. She also had constitutional features including anorexia, weight loss, and profound lethargy. She was a smoker with a 30 pack year history. Initial blood tests showed markedly raised inflammatory markers, with an erythrocyte sedimentation rate of 98 mm in the first hour (reference range 0-12) and C reactive protein of 933 nmol/L (0-47.6). A diagnosis of polymyalgia rheumatica was considered.  
feeds.bmj.com
almost 5 years ago
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Fibromyalgia

One page summary of Fibromyalgia  
oneminutemedicalschool.com
almost 5 years ago
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Markers for Giant Cell Arteritis and Polymyalgia Rheumatica

Which biological markers are associated with disease activity in giant cell arteritis and polymyalgia rheumatica?  
medscape.com
almost 5 years ago
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Apremilast for Psoriasis and Psoriatic Arthritis

An overview of the use, safety, and efficacy of the PDE4 inhibitor apremilast, a promising new systemic therapy for treating psoriatic disease.  
medscape.com
almost 5 years ago
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Hip Surgery Safe, Effective in Psoriatic Arthritis

Outcomes after hip replacement surgery are as good in patients with psoriatic arthritis or cutaneous psoriasis as in patients with OA; surgeons should not avoid offering replacement surgery as needed.  
medscape.com
almost 5 years ago
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In brief

Stem cell trial in unborn babies will start next year: A clinical trial that will involve injecting fetal stem cells into fetuses identified with brittle bone disease is to begin in January. The trial, led by Sweden’s Karolinska Institute and Great Ormond Street Hospital in London, will use stem cells from terminated pregnancies that develop into healthy bone, cartilage, and muscle. Brittle bone disease affects around one in 25 000 births and can be fatal. It can cause multiple fractures and other problems.  
feeds.bmj.com
almost 5 years ago
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In brief

Stem cell trial in unborn babies will start next year: A clinical trial that will involve injecting fetal stem cells into fetuses identified with brittle bone disease is to begin in January. The trial, led by Sweden’s Karolinska Institute and Great Ormond Street Hospital in London, will use stem cells from terminated pregnancies that develop into healthy bone, cartilage, and muscle. Brittle bone disease affects around one in 25 000 births and can be fatal. It can cause multiple fractures and other problems.  
feeds.bmj.com
almost 5 years ago
Preview
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0

In brief

Stem cell trial in unborn babies will start next year: A clinical trial that will involve injecting fetal stem cells into fetuses identified with brittle bone disease is to begin in January. The trial, led by Sweden’s Karolinska Institute and Great Ormond Street Hospital in London, will use stem cells from terminated pregnancies that develop into healthy bone, cartilage, and muscle. Brittle bone disease affects around one in 25 000 births and can be fatal. It can cause multiple fractures and other problems.  
feeds.bmj.com
almost 5 years ago
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9

Renal Involvement in Primary Sjogren's Syndrome

Renal involvement in Sjogren's syndrome is an underdiagnosed problem. Read about the presentation, pathogenesis and treatment here.  
medscape.com
almost 5 years ago
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H3K18 Acetylation in Epithelial Cells of Asthmatic Subjects

What's the interaction between histone modifications and gene regulation in asthma?  
medscape.com
almost 5 years ago
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Hyaluronic acid and other non-surgical treatment options for ankle osteoarthritis | Cochrane

Cochrane researchers conducted a review of the effect of non-surgical treatment for people older than 18 with ankle osteoarthritis in order to provide a synthesis of the evidence as a base for future treatment guidelines. After searching for all relevant studies up to September 2014, no study using any other non-surgical treatment besides the use of hyaluronic acid for ankle osteoarthritis was identified. They found six studies evaluating hyaluronic acid with a total of 240 people. Their findings are summarised below:  
cochrane.org
almost 5 years ago
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Imaging Case of the Week 175

The following right foot x-ray is from an eighty year old with pain and swelling over the right 1st MTP joint. What can be seen?  
emergucate.com
almost 5 years ago
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Milnacipran for fibromyalgia in adults | Cochrane

Fibromyalgia is characterised by persistent, widespread pain and tenderness, sleep problems, and fatigue. Common pain-relieving medicines such as paracetamol and ibuprofen are not usually considered effective. Medicines used to treat epilepsy or depression can be effective in some people with fibromyalgia and other forms of chronic (persistent, long-lasting) pain where there may be nerve damage. Milnacipran is an antidepressant, and antidepressants are widely recommended for treating fibromyalgia. Milnacipran is licensed to treat fibromyalgia only in some parts of the world, particularly the USA.  
cochrane.org
almost 5 years ago
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GI Flora and Arthritis Pattern in Spondyloarthropathy

Do patterns of arthritis correlate with gastrointestinal flora?  
medscape.com
almost 5 years ago