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8

Topical tacrolimus for atopic dermatitis | Cochrane

Atopic dermatitis (AD) (or atopic eczema) is a chronic skin condition that affects the quality of life of both adults and children. Topical corticosteroids (TCS) are the main ointments used for treatment, but there is a risk of side-effects with their use, such as skin thinning. A class of drugs called topical calcineurin inhibitors, which include topical tacrolimus (and pimecrolimus), might provide an alternative to this problem, but since tacrolimus is a newer ointment compared with corticosteroids, there are still some questions about its effectiveness and safety.  
cochrane.org
over 6 years ago
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9

Fish oil (n-3 or omega-3) for pregnant mothers or breastfeeding mothers to prevent allergies in their young children | Cochrane

Fish and fish oil are the major sources of omega-3 long chain fatty acids. Dietary marine omega-3 fatty acid supplements during pregnancy may change the immune system of the newborn before allergic responses are established, particularly for those with a genetic predisposition to the production of the immunoglobulin E (IgE) antibody. Individuals with IgE-mediated allergies have both the signs and symptoms of the allergic disease and a positive skin prick test (SPT) to the allergen.  
cochrane.org
over 6 years ago
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19

Falsely elevated capillary glucose and ketone levels and use of skin lightening creams

Hyperglycaemia associated with ketosis reflects severe insulin deficiency that mandates immediate insulin therapy. Point-of-care devices to measure capillary glucose have become essential in diabetes management.1 Management of hyperglycaemic crisis has also been improved by the measurement of β-hydroxybutyrate in a fingerprick blood specimen. The method is quick, accurate, and reliable,2 3 4 and recommended to medical care providers and patients.2 5 6 Here we report two cases of misleadingly high capillary glucose and ketone measurements that could have been prevented by careful hand washing. We also identify the chemical compound, hydroquinone, that interferes with capillary results.  
feeds.bmj.com
over 6 years ago
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17

Rash on the arms and legs

An 11 year old girl presented to her general practitioner with painful skin lesions on her arms (fig A⇓) and legs (fig B). She had a three week history of an upper respiratory illness and had been started on amoxicillin for presumed lower respiratory tract infection. Three days after starting treatment, she re-attended with a rash on her arms and legs; her parents were worried that it was caused by a drug allergy. Apart …  
feeds.bmj.com
over 6 years ago
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Oral fumaric acid esters for the treatment of psoriasis | Cochrane

Psoriasis is a long-term inflammatory skin condition that can markedly reduce the quality of life of affected individuals. Treatments taken by mouth (oral treatments), such as methotrexate, ciclosporin, and acitretin, are commonly prescribed to people with moderate to severe psoriasis. Oral fumaric acid esters (FAE) are licensed for the treatment of psoriasis in Germany but remain unlicensed in most other countries. This means that there are different treatment options offered to people in different countries.  
cochrane.org
over 6 years ago
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3

Elastic Material Sticks to Skin, Releases Drugs When Stretched |

A team of investigators from North Carolina State University and the University of North Carolina at Chapel Hill have designed a novel drug release technol  
medgadget.com
over 6 years ago
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2

Food allergy week #4 – management of food allergy in infants – Don't Forget the Bubbles

Brayden is a 3 year old boy who has been referred to your clinic following one occasion where he developed some facial swelling and wheeze after ingesting peanuts. Brayden’s allergy has been confirmed on skin prick testing. Brayden’s mum is pregnant, and is wondering how to prevent her second child from having a food allergy.  
dontforgetthebubbles.com
over 6 years ago