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1
22

Painful diabetic neuropathy

Diabetes is a worldwide epidemic, and associated neuropathy is its most costly and disabling complication. Given the rising prevalence of painful diabetic neuropathy, it is increasingly important that we understand the best ways to diagnose and treat this condition. Diagnostic tests in this field are evolving rapidly. These include the use of skin biopsies to measure small unmyelinated fibers, as well as even newer techniques that can measure both small unmyelinated fibers and large myelinated fibers in the same biopsy. The main treatments for painful diabetic neuropathy remain management of the underlying diabetes and drugs for the relief of pain. However, emerging evidence points to major differences between type 1 and type 2 diabetes, including the ability of glycemic control to prevent neuropathy. Enhanced glucose control is much more effective at preventing neuropathy in patients with type 1 diabetes than in those with type 2 disease. This dichotomy emphasizes the need to study the pathophysiologic differences between the two types of diabetes, because different treatments may be needed for each condition. The impact of the metabolic syndrome on neuropathy in patients with type 2 diabetes may account for the difference between the two types of diabetes and requires further study. Finally, neuropathic pain is under-recognized and undertreated despite an ever evolving list of effective drugs. Evidence exists to support several drugs, but the optimal sequence and combination of these drugs are still to be determined.  
www.bmj.com
over 6 years ago
Preview
1
19

Painful diabetic neuropathy

Diabetes is a worldwide epidemic, and associated neuropathy is its most costly and disabling complication. Given the rising prevalence of painful diabetic neuropathy, it is increasingly important that we understand the best ways to diagnose and treat this condition. Diagnostic tests in this field are evolving rapidly. These include the use of skin biopsies to measure small unmyelinated fibers, as well as even newer techniques that can measure both small unmyelinated fibers and large myelinated fibers in the same biopsy. The main treatments for painful diabetic neuropathy remain management of the underlying diabetes and drugs for the relief of pain. However, emerging evidence points to major differences between type 1 and type 2 diabetes, including the ability of glycemic control to prevent neuropathy. Enhanced glucose control is much more effective at preventing neuropathy in patients with type 1 diabetes than in those with type 2 disease. This dichotomy emphasizes the need to study the pathophysiologic differences between the two types of diabetes, because different treatments may be needed for each condition. The impact of the metabolic syndrome on neuropathy in patients with type 2 diabetes may account for the difference between the two types of diabetes and requires further study. Finally, neuropathic pain is under-recognized and undertreated despite an ever evolving list of effective drugs. Evidence exists to support several drugs, but the optimal sequence and combination of these drugs are still to be determined.  
www.bmj.com
over 6 years ago
Preview
1
54

Painful diabetic neuropathy

Diabetes is a worldwide epidemic, and associated neuropathy is its most costly and disabling complication. Given the rising prevalence of painful diabetic neuropathy, it is increasingly important that we understand the best ways to diagnose and treat this condition. Diagnostic tests in this field are evolving rapidly. These include the use of skin biopsies to measure small unmyelinated fibers, as well as even newer techniques that can measure both small unmyelinated fibers and large myelinated fibers in the same biopsy. The main treatments for painful diabetic neuropathy remain management of the underlying diabetes and drugs for the relief of pain. However, emerging evidence points to major differences between type 1 and type 2 diabetes, including the ability of glycemic control to prevent neuropathy. Enhanced glucose control is much more effective at preventing neuropathy in patients with type 1 diabetes than in those with type 2 disease. This dichotomy emphasizes the need to study the pathophysiologic differences between the two types of diabetes, because different treatments may be needed for each condition. The impact of the metabolic syndrome on neuropathy in patients with type 2 diabetes may account for the difference between the two types of diabetes and requires further study. Finally, neuropathic pain is under-recognized and undertreated despite an ever evolving list of effective drugs. Evidence exists to support several drugs, but the optimal sequence and combination of these drugs are still to be determined.  
www.bmj.com
over 6 years ago
Preview
1
15

Painful diabetic neuropathy

Diabetes is a worldwide epidemic, and associated neuropathy is its most costly and disabling complication. Given the rising prevalence of painful diabetic neuropathy, it is increasingly important that we understand the best ways to diagnose and treat this condition. Diagnostic tests in this field are evolving rapidly. These include the use of skin biopsies to measure small unmyelinated fibers, as well as even newer techniques that can measure both small unmyelinated fibers and large myelinated fibers in the same biopsy. The main treatments for painful diabetic neuropathy remain management of the underlying diabetes and drugs for the relief of pain. However, emerging evidence points to major differences between type 1 and type 2 diabetes, including the ability of glycemic control to prevent neuropathy. Enhanced glucose control is much more effective at preventing neuropathy in patients with type 1 diabetes than in those with type 2 disease. This dichotomy emphasizes the need to study the pathophysiologic differences between the two types of diabetes, because different treatments may be needed for each condition. The impact of the metabolic syndrome on neuropathy in patients with type 2 diabetes may account for the difference between the two types of diabetes and requires further study. Finally, neuropathic pain is under-recognized and undertreated despite an ever evolving list of effective drugs. Evidence exists to support several drugs, but the optimal sequence and combination of these drugs are still to be determined.  
www.bmj.com
over 6 years ago
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1
16

An unusual variant of Guillain–Barré syndrome, and dopamine dysregulation syndrome

Stream An unusual variant of Guillain–Barré syndrome, and dopamine dysregulation syndrome by BMJ talk medicine from desktop or your mobile device  
SoundCloud
over 6 years ago
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1
23

5.1.c. Brady/Tachy Syndrome - Bradyarrhythmias [Hong Kong University]

All videos of this series: http://doctorprodigious.wordpress.com/2014/04/17/arrhythmias-and-pacemaker-basics-hong-kong-university/  
YouTube
over 6 years ago
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1
51

Entrapment of Radial Nerve, Wartenberg's Syndrome - Everything You Need To Know - Dr. Nabil Ebraheim

Educational video describing entrapment of the superficial radial nerve of the forearm. Wartenberg's Syndrome. Become a friend on facebook: http://www.facebo...  
YouTube
over 6 years ago
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1
6

Central cord syndrome- Real patient case

Patient presents with upper extremity weakness and loss of sensation. This syndrome most often occurs after a hyperextension injury in an individual with lon...  
YouTube
over 6 years ago
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1
21

Saudi fears rise over mystery virus - BBC News

A mystery virus known as the Middle East Respiratory Syndrome (Mers) has claimed an increasing number of lives in Saudi Arabia, where fear of the condition is growing, as the BBC's Gulf correspondent Mark Lobel reports from Dubai.  
BBC News
over 6 years ago
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1
18

Mers virus found in second Heathrow transit passenger - BBC News

A second case emerges of a passenger who travelled through Heathrow Airport and later tested positive for the Middle East Respiratory Syndrome (Mers) virus.  
BBC News
over 6 years ago
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1
34

Mers virus: World health chiefs mull emergency warning - BBC News

The World Health Organization has been meeting to decide whether to declare a public health emergency after a sudden spike in cases of a deadly virus known as Middle East Respiratory Syndrome, or Mers.  
BBC News
over 6 years ago
8
1
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WHO | WHO statement on the Fifth Meeting of the IHR Emergency Committee concerning MERS-CoV

The fifth meeting of the Emergency Committee convened by the Director-General under the International Health Regulations (2005) concerning Middle East respiratory syndrome coronavirus (MERS-CoV) was held by teleconference on Tuesday, 13 May 2014, from 12:07 to 17:12 Geneva time (CEST).  
who.int
over 6 years ago
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1
10

Iran confirms first cases of deadly Mers infection - BBC News

Iranian officials say they have confirmed their country's first two cases of Middle East respiratory syndrome.  
BBC News
over 6 years ago
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1
16

Cats and dogs to be tested for mysterious Mers infection - BBC News

Scientists are soon to test cats, dogs and even rats as they seek to understand the deadly Middle East Respiratory Syndrome.  
BBC News
over 6 years ago
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1
9

Night-eating syndrome 'is real', study suggests - BBC News

People woken at night by insatiable hunger may have their genes to blame, research suggests.  
BBC News
over 6 years ago
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1
15

Wartenberg's Sign - Everything You Need To Know - Dr. Nabil Ebraheim

Educational video describing the difference between Warteberg's Sign and Wartentberg's Syndrome. Become a friend on facebook: http://www.facebook.com/drebrah...  
YouTube
over 6 years ago
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1
13

An unusual variant of Guillain–Barré syndrome, and dopamine dysregulation syndrome

Stream An unusual variant of Guillain–Barré syndrome, and dopamine dysregulation syndrome by BMJ talk medicine from desktop or your mobile device  
SoundCloud
over 6 years ago
Preview
1
25

Internal medicine on Instagram: “Severe xerostomia with dry tongue and angular chelitis in Sjögren's syndrome. This patient with Sjögren's syndrome not only has a…”

“Severe xerostomia with dry tongue and angular chelitis in Sjögren's syndrome. This patient with Sjögren's syndrome not only has a profoundly dry tongue,…”  
Instagram
over 6 years ago
Www.bmj
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3

Managing the care of adults with Down’s syndrome

The approach to primary care for adults with Down’s syndrome is similar to that for the general adult population, with the addition of screening for conditions specific to Down’s syndrome  
bmj.com
almost 6 years ago
12
1
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WHO | WHO statement on the Seventh Meeting of the IHR Emergency Committee regarding MERS-CoV

The seventh meeting of the Emergency Committee (EC) convened by the Director-General under the International Health Regulations (IHR 2005) regarding the Middle East respiratory syndrome coronavirus (MERS-CoV) was conducted with members and advisors of the Emergency Committee through electronic correspondence from 26 September 2014 through 30 September 2014.  
who.int
almost 6 years ago