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Therapeutics

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NHS will not fund anti-HIV Prep drug plan - BBC News

Charities express anger after NHS England confirms it will not fund a "game-changer" drug treatment that can prevent HIV.  
bbc.co.uk
over 3 years ago
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Insulin in Clinical Practice: Where Does It Fit? CME

: Self-assess your knowledge of and competence in the use of basal insulin in the treatment of diabetes, barriers to early insulin use, and the role of the new basal insulin formulations.  
medscape.org
over 3 years ago
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FDA OKs Linagliptin/Metformin Combo for Type 2 Diabetes

Approval is for the treatment of adults with type 2 diabetes as adjunct to diet and exercise.  
medscape.com
over 3 years ago
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GnRH Agonist Fails to Save Fertility in Lymphoma Patients

After 5 years of follow-up, GnRHa treatment did not prevent chemotherapy-induced premature ovarian failure in young women with lymphoma, a result that contrasts with findings from other studies.  
medscape.com
over 3 years ago
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FDA Clears Obeticholic Acid for Primary Biliary Cholangitis

The first new treatment in almost 20 years for the condition, Ocaliva is for use in combination with UDCA in adults with poor response to UDCA or as a single therapy in adults unable to tolerate UDCA.  
medscape.com
over 3 years ago
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Treatment Algorithms Based on Tumor Molecular Profiling

Which molecular, biological, and technical criteria should be evaluated in studies using genomic medicine for cancer treatment?  
medscape.com
over 3 years ago
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UMEM Educational Pearls - University of Maryland School of Medicine, Department of Emergency Medicine

Pick a category... Airway Management Cardiology Critical Care Critical Care Literature Update Dermatology Endocrine ENT Financial & Investing Gastrointestional Geriatrics Hematology/Oncology Infectious Disease International EM Med-Legal Medical Education Misc Neurology Obstetrics & Gynecology Ophthamology Orthopedics Pediatrics Pharmacology & Therapeutics Procedures Pulmonary Toxicology Trauma Urology Vascular Visual Diagnosis $('#pearl_categories').change(function(){ window.location = "/educational_pearls/search/?category=" + $(this).val() });  
umem.org
over 3 years ago
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Effect of Continued Treatment With Pirfenidone in IPF

Do idiopathic pulmonary fibrosis patients benefit from continued treatment with pirfenidone -- particularly those who experienced meaningful disease progression during treatment?  
medscape.com
over 3 years ago
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Cardiovascular safety of methylphenidate among children and young people with attention-deficit/hyperactivity disorder (ADHD): nationwide self controlled case series study

Objective To determine whether treatment with methylphenidate in children and young people with attention-deficit/hyperactivity disorder (ADHD) was associated with cardiovascular events.  
feeds.bmj.com
over 3 years ago
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Cardiovascular safety of methylphenidate among children and young people with attention-deficit/hyperactivity disorder (ADHD): nationwide self controlled case series study

Objective To determine whether treatment with methylphenidate in children and young people with attention-deficit/hyperactivity disorder (ADHD) was associated with cardiovascular events.  
feeds.bmj.com
over 3 years ago
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Advances in Inflammatory Bowel Disease Therapeutics

A number of practice-changing studies have been presented at this year's Digestive Disease Week. Dr Steve Hanauer discusses some of the latest therapeutic advances for inflammatory bowel disease.  
medscape.com
over 3 years ago
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Surgery vs Medical Therapy for Type 2 Diabetes

Commentary on a study comparing bariatric surgery vs conventional treatment for type 2 diabetes in obese patients, published in the Lancet.  
medscape.com
over 3 years ago
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Lung Cancer Sessions Focus on Immunotherapy, Genomics

From diagnosis using molecular markers to targeted treatment, Dr Mark Kris details which studies from ASCO 2016 he thinks will help clinicians and patients fight lung cancer.  
medscape.com
over 3 years ago
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Exome Sequencing and Neurometabolic Disorder Abnormalities

Exome sequencing can identify abnormalities, many of which can alter treatment, in most individuals with intellectual developmental disorder resulting from neurometabolic disorders, researchers report.  
medscape.com
over 3 years ago
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Care Transitions in Long-term Care and Acute Care

Long-term care settings are behind in their use of health information technologies, creating another obstacle during patient care transitions.  
medscape.com
over 3 years ago
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Palliative Pharmacotherapy: State-of-the-Art Management

Managing symptoms of advanced cancer can greatly improve patient quality of life. This review describes the latest therapy for cachexia, anorexia, fatigue, delirium, and dyspnea.  
medscape.com
over 3 years ago
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Feedback-informed Treatment in Emergency Psychiatry

This study investigated the efficacy of an immediate feedback instrument in the treatment of patients with acute, severe psychosocial or psychiatric problems in a crisis situation.  
medscape.com
over 3 years ago
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Statins could be new treatment option in women with oestrogen receptor positive breast cancer

Researchers have called for clinical trials into the effects of statins in women with recurrent breast cancer, after finding that these cancers can make a molecule from cholesterol that mimics oestrogen.  
feeds.bmj.com
over 3 years ago
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The Dangers of Over-Resuscitation in Sepsis - emdocs

In previous discussions, we have addressed that IV fluid choices affect patient outcomes in septic shock, and we have shown the evidence that invasive monitoring coupled with aggressive treatments are actually harming our patients.  The question we now face is what is the result of over-resuscitation?   
emdocs.net
over 3 years ago
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Triptan and DHE Use for Basilar and Hemiplegic Migraine

Are triptans and DHE safe to use for the abortive treatment of basilar and hemiplegic migraine?  
medscape.com
over 3 years ago