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Therapeutics

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Current concepts in the pathophysiology of glaucoma

Glaucoma, the second leading cause of blindness, is characterized by changes in the optic disc and visual field defects. The elevated intraocular pressure was considered the prime factor responsible for the glaucomatous optic neuropathy involving death of retinal ganglion cells and their axons. Extensive investigations into the pathophysiology of glaucoma now reveal the role of multiple factors in the development of retinal ganglion cell death. A better understanding of the pathophysiological mechanisms involved in the onset and progression of glaucomatous optic neuropathy is crucial in the development of better therapeutic options. This review is an effort to summarize the current concepts in the pathophysiology of glaucoma so that newer therapeutic targets can be recognized.  
ncbi.nlm.nih.gov
over 3 years ago
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Fluoroquinolones: Not First-Line Treatment

Dr Paul Auwaerter comments on the FDA advisory with new warnings about the use of fluoroquinolones.  
medscape.com
over 3 years ago
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Metabolic Markers May Help Guide Treatment in Trauma Patients

Metabolomics, the study of the small molecules involved in metabolism, may help guide treatment decisions in trauma patients, according to Seattle-based researchers.  
medscape.com
over 3 years ago
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Impact of Fibromyalgia in Spondyloarthritis

How does fibromyalgia affect the disease activity and treatment of spondyloarthritis?  
medscape.com
over 3 years ago
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The Expanding Therapeutics of Interleukin-1 Blockade

Indications for IL-1 blocking therapies are broadening. Read about the established and emerging uses of IL-1 antagonism in rheumatic diseases.  
medscape.com
over 3 years ago
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Benzodiazepine Pharmacotherapy: How Difficult to Discontinue?

What is the optimal strategy for discontinuing chronic benzodiazepine therapy in the primary care setting?  
medscape.com
over 3 years ago
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Cancer Drug Global Sales Grow, But 'Tension in the System'

An unprecedented and sustained surge in innovative oncology therapeutics reaching the market is creating challenges for health systems and oncologists.  
medscape.com
over 3 years ago
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Stem cells used in stroke treatment - BBC News

A great-grandfather becomes one of the first in the UK to be treated for a stroke, using stem cells.  
bbc.co.uk
over 3 years ago
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In Pancreatic Cancer, a 'Step' Means a New Standard of Care

Progress is being made in the treatment of the 'ruthless dictator of all cancers.'  
medscape.com
over 3 years ago
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Chemoradiotherapy for Stage III NSCLC

Outcomes in patients with stage III NSCLC need to be improved. What works and what doesn't?  
medscape.com
over 3 years ago
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Arthritis of the Hand

Arthritis can damage the large joints on your hand at the base of the fingers. If other treatments don't relieve your pain, your doctor may advise artificial...  
youtube.com
over 3 years ago
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Spinal Tap Procedure (Lumbar Puncture)

A spinal tap, also called lumbar puncture, is used to take a sample of the fluid from the spinal column to look for infection or bleeding.  
youtube.com
over 3 years ago
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Managing Pain in Frail Elders

We face barriers in the assessment, treatment and evaluation of pain in elders. Read how to overcome these barriers here.  
medscape.com
over 3 years ago
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Renal Replacement Therapy -- Sooner or Later?

Should renal replacement therapy be initiated early to improve outcomes?  
medscape.com
over 3 years ago
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Frontalis Sling for the Treatment of Congenital Ptosis

In this case, the frontalis sling procedure was used to correct congenital ptosis of the right upper eyelid.  
medscape.com
over 3 years ago
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What Will You Tell Breast Cancer Patients About MA-17R?

A major clinical trial indicates that 5 more years of an aromatase inhibitor in postmenopausal women yields a disease-free survival benefit as well as adverse events. Is the treatment worthwhile?  
medscape.com
over 3 years ago
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Post-Intubation Complications in ED Setting - emdocs

We are masters of the airway, often managing life-threatening scenarios and conditions. However, the patient who decompensates around the time of intubation, or directly after the procedure, can be frightening. What can you do to mimize these events?  
emdocs.net
over 3 years ago
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Bubbly drink trial 'to boost cancer therapy' - BBC News

Scientists are investigating whether bubbly drinks could boost the success of cancer treatments, after winning a Cancer Research UK award for "outside the box" ideas.  
bbc.co.uk
over 3 years ago