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Stem Cell Transplantation in Severe Congenital Neutropenia: An Analysis From the European Society for Blood and Marrow Transplantation: Abstract and Introduction

Abstract and Introduction: Matched donor hematopoietic stem cell transplantation has a good outcome in severe congenital neutropenia, but careful patient selection is needed because of high transplant-related mortality.  
medscape.org
about 5 years ago
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Transplant Drug Ups Risk for CNS Lymphoma

Mycophenolate mofetil may be linked to higher risk for primary central nervous system lymphoma in patients who have undergone solid organ transplants.  
medscape.com
about 5 years ago
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Faecal transplants

Recurrent Clostridium difficile infection is a severe and often fatal condition, affecting up to 3000 people in the United Kingdom and 100 000 in the United States, where it kills an estimated 14 000 a year.1 About a quarter of patients experience a recurrence after an initial mild infection because treatment with antibiotics destroys the diversity of the normal gut microbes and allows C difficile to flourish.  
feeds.bmj.com
about 5 years ago
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Faecal transplants

Recurrent Clostridium difficile infection is a severe and often fatal condition, affecting up to 3000 people in the United Kingdom and 100 000 in the United States, where it kills an estimated 14 000 a year.1 About a quarter of patients experience a recurrence after an initial mild infection because treatment with antibiotics destroys the diversity of the normal gut microbes and allows C difficile to flourish.  
feeds.bmj.com
about 5 years ago
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Long-term Effects of Fecal Transplants Questioned

Fecal transplants are increasingly being used to treat Clostridium difficile infection and other ailments, but experts said the science lags dramatically behind practice.  
medscape.com
about 5 years ago
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Mixed Results for Fecal Transplant in First Randomized Trial

Fecal transplantation helped some patients with recurrent C difficile infection, but not others, in the first randomized trial of its kind.  
medscape.com
about 5 years ago
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Critical limb ischaemia in peripheral vascular disease: intravenous iloprost | key-points-from-the-evidence | Advice | NICE

A Cochrane review of low quality studies of prostanoids in people with critical limb ischaemia unsuitable for surgery found that compared with placebo, intravenous iloprost statistically significantly reduced major amputations, improved rest-pain relief, and improved ulcer healing. The benefit of intravenous iloprost on total amputations (major plus minor) was not statistically significant. In a randomised controlled trial (RCT) in people undergoing femorodistal bypass surgery for critical limb ischaemia, perioperative intravenous and intra-graft iloprost did not improve graft patency or clinical status, or reduce amputations at 1‑year follow-up compared with placebo. Adverse events were more common with intravenous iloprost than with placebo and included pain at the infusion site, headache, flushing, nausea and vomiting, and hypotension.  
nice.org.uk
almost 5 years ago
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PROPATEN heparin-bonded vascular graft for peripheral arterial disease | Advice | NICE

NICE has developed a medtech innovation briefing (MIB) on the PROPATEN heparin-bonded vascular graft for peripheral arterial disease.  
nice.org.uk
almost 5 years ago
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Spiral Flow peripheral vascular graft for treating peripheral arterial disease | Advice | NICE

NICE has developed a medtech innovation briefing (MIB) on the Spiral Flow peripheral vascular graft for treating peripheral arterial disease.  
nice.org.uk
almost 5 years ago
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Depression Common in Patients Awaiting Lung Transplant

More than half of patients waiting for a lung transplant suffered from psychologic stress in a new study, which might be serious enough to affect transplant outcomes.  
medscape.com
almost 5 years ago
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Development and Detection of Kidd Antibodies

This case study of a 59-year-old kidney transplant patient reviews the development and detection of Kidd antibodies associated with kidney-graft rejection.  
medscape.com
almost 5 years ago
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Nasal Mucosa Graft to Deliver Drugs Through Blood-Brain Barrier |

As is well known, the blood-brain barrier is a strict checkpoint that prevents variety of drugs from reaching the brain. At the Massachusetts Eye and Ear/H  
medgadget.com
almost 5 years ago
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Three Heart Transplants for One Child While Others Get None?

With many more children needing heart transplants than hearts are available, should one child receive not one transplant but three, as the odds of success diminish? See what your colleagues think.  
medscape.com
almost 5 years ago
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Pancreas Allocation for Whole Organ and Islet Transplantation

Learn more about factors that impact waiting time for pancreas and islet cell transplants.  
medscape.com
almost 5 years ago
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FMT for Recurrent C. Difficile Infection Using Frozen Stool

Is fecal microbiota transplant using frozen stool effective in the treatment of recurrent C. difficile infection?  
medscape.com
almost 5 years ago
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Critical Care

APACHE II Acute Physiology and Chronic Health Evaluation II, CABG coronary artery bypass graft, CPB cardiopulmonary bypass  
ccforum.com
almost 5 years ago
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Interventions for metabolic bone disease in children with chronic kidney disease | Cochrane

Chronic kidney disease (CKD) resulting in reduced kidney function and the need for dialysis and kidney transplant is associated with abnormalities in serum calcium and phosphorus levels leading to high levels of the parathyroid hormone (PTH) and to bone disease. This may result in bone deformities, bone pain, fractures and reduced growth rates. Commonly used treatments (vitamin D compounds and phosphate binders) aim to prevent or correct these outcomes. However, these treatments may raise levels of blood calcium, allow calcium and phosphorus deposition in blood vessels and lead to early cardiovascular disease, which is known to be a problem in adults with CKD.  
cochrane.org
almost 5 years ago
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Firefighter receives full face transplant in surgery called 'historic'

Ninety-three days after transplant, surgeons say Patrick Hardison, a retired fireman injured when a burning roof collapsed on him, is making a full recovery  
theguardian.com
almost 5 years ago
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The man with a new face after 'world's most extensive' transplant - BBC News

A US firefighter, who suffered severe burns while attempting to save a woman, has a new face after undergoing the world's most extensive facial transplant.  
bbc.co.uk
almost 5 years ago
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Uterus Transplant: First US Clinical Trial Begins

The first clinical trial of uterus transplantation in the United States has begun at Cleveland Clinic in Ohio.  
medscape.com
almost 5 years ago