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21

Call to end vaccine 'nightmare' - BBC News

The need to keep child vaccines cold is hampering immunisation campaigns around the world, a charity warns.  
BBC News
over 5 years ago
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US vaccine program will prevent 732 000 deaths, CDC says

A program set up 20 years ago to provide vaccines to children from low income families in the United States will ultimately prevent 732 000 deaths from vaccine preventable diseases among children born in the past two decades, says a new report by the Centers for Disease Control and Prevention.1  
bmj.com
over 5 years ago
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Non-publication and delayed publication of randomized trials on vaccines: survey

Objective To evaluate the extent of non-publication or delayed publication of registered randomized trials on vaccines, and to investigate potential determinants of delay to publication.  
bmj.com
over 5 years ago
Www.bmj
1
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Delayed publication of vaccine trials

Among medical interventions to improve human health, vaccination has been and remains one of the most important.1 Given the huge number of deaths from influenza pandemics in recent history, the ability to rapidly develop effective vaccines for new strains of influenza is particularly critical. Making and testing a new influenza vaccine that can be administered to the public takes six months or less.2 For example, the pandemic A/H1N1 2009 influenza strain was first identified in April of 2009; four vaccines were approved by the US Food and Drug Administration in September. After the approval of a vaccine, however, important questions remain regarding dosage, effectiveness, and safety. These questions are best answered by randomized clinical trials, and getting complete results from these trials to policy makers, clinicians, and the general public in a timely manner is essential.  
bmj.com
over 5 years ago
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WHO | New study sheds light on the importance of supportive care for Ebola patients

Evidence is mounting that earlier messages about Ebola virus disease having no treatment, cure, or vaccines are no longer entirely accurate.  
who.int
about 5 years ago
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WHO | WHO convenes industry leaders and key partners to discuss trials and production of Ebola vaccine

WHO convened a meeting with high-ranking government representatives from Ebola-affected countries and development partners, civil society, regulatory agencies, vaccine manufacturers and funding agencies yesterday to discuss and agree on how to fast track testing and deployment of vaccines in sufficient numbers to impact the Ebola epidemic.  
who.int
about 5 years ago
Www.bmj
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27

Do we need a new approach to making vaccine recommendations?

Controversy about the evidence, economics, ethics, lobbying, and decision making surrounding a new vaccine for serogroup B meningococcal disease should trigger change in the way we develop recommendations for new vaccines say Natasha Crowcroft and colleagues  
bmj.com
over 4 years ago
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WHO | WHO calls for increased transparency in medical research

WHO today issued a public statement calling for the disclosure of results from clinical trials for medical products, whatever the result.The move aims to ensure that decisions related to the safety and efficacy of vaccines, drugs and medical devices for use by populations are supported by the best available evidence.  
who.int
over 4 years ago
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11

Measles, Vaccines, Antibodies and Big Pharma Money

Measles, Vaccines, Antibodies and Big Pharma Money Did you know that the AMA strongly discourages ANY comments by Medical Professionals that cast any doubt o...  
youtube.com
over 4 years ago
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How to Educate Yourself on Measles and Vaccines

How to Educate Yourself on Measles and Vaccines Is measles really as deadly as "they" would have you think? Did you know that not a single person has died fr...  
youtube.com
over 4 years ago
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MMR vaccine and autism: study finds 'no harmful association'

In a study of more than 95,000 children, researchers found no link between the MMR vaccine and greater risk of autism, even among children at higher risk for the condition.  
medicalnewstoday.com
over 4 years ago
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Selecting the right tool for the job: The ethical conundrum surrounding drug trials during deadly, rapidly spreading infectious disease

Randomized clinical trials of new drugs have long been considered the 'gold standard' in determining safety and efficacy before drugs, biologics, vaccines or devices are introduced to the...  
medicalnewstoday.com
over 4 years ago
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Evidence supports it, so why are parents still reluctant to vaccinate their children?

Controversy over adverse effects of vaccines has reignited across the media recently. New studies also investigate the influence this information has on the decision to vaccinate.  
medicalnewstoday.com
over 4 years ago
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Can cancer vaccines prolong survival?

Therapeutic anti-cancer vaccines developed to treat metastatic disease such as advanced prostate cancer or melanoma rarely have a noticeable effect on the tumor but have been associated with a...  
medicalnewstoday.com
over 4 years ago
Dt 150420 vaccine baby child toddler 800x600
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MMR Vaccine Not Linked to Autism, Even in High-Risk Kids

Receipt of the MMR vaccine was not linked to an increased risk for autism spectrum disorder, even when older siblings had the disorder, a new study has shown.  
medscape.com
over 4 years ago
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Morning Break: Elmo Champions Vaccines; Military Medicine Under Fire

Health news and commentary from around the Web, gathered by the <em>MedPage Today</em> staff.  
medpagetoday.com
over 4 years ago
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Heart doctor admits vaccines are dangerous

Heart doctor admits vaccines are dangerous  
naturalnews.com
over 4 years ago
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Cancer vaccines

Cancer vaccines are designed to promote tumor specific immune responses, particularly cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines, which were developed in 1994-95, tested non-mutated, shared tumor associated antigens that had been shown to be immunogenic and capable of inducing clinical responses in a minority of people with late stage cancer. Technological developments in the past few years have enabled the investigation of vaccines that target mutated antigens that are patient specific. Several platforms for cancer vaccination are being tested, including peptides, proteins, antigen presenting cells, tumor cells, and viral vectors. Standard of care treatments, such as surgery and ablation, chemotherapy, and radiotherapy, can also induce antitumor immunity, thereby having cancer vaccine effects. The monitoring of patients’ immune responses at baseline and after standard of care treatment is shedding light on immune biomarkers. Combination therapies are being tested in clinical trials and are likely to be the best approach to improving patient outcomes.  
feeds.bmj.com
over 4 years ago
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Vaccines to prevent influenza in healthy adults | Cochrane

We evaluated the effect of immunisation with influenza vaccines on preventing influenza A or B infections (efficacy), influenza-like illness (ILI) and its consequences (effectiveness), and determined whether exposure to influenza vaccines is associated with serious or severe harms. The target populations were healthy adults, including pregnant women and newborns.  
cochrane.org
over 4 years ago
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13

Cancer vaccines

Cancer vaccines are designed to promote tumor specific immune responses, particularly cytotoxic CD8 positive T cells that are specific to tumor antigens. The earliest vaccines, which were developed in 1994-95, tested non-mutated, shared tumor associated antigens that had been shown to be immunogenic and capable of inducing clinical responses in a minority of people with late stage cancer. Technological developments in the past few years have enabled the investigation of vaccines that target mutated antigens that are patient specific. Several platforms for cancer vaccination are being tested, including peptides, proteins, antigen presenting cells, tumor cells, and viral vectors. Standard of care treatments, such as surgery and ablation, chemotherapy, and radiotherapy, can also induce antitumor immunity, thereby having cancer vaccine effects. The monitoring of patients’ immune responses at baseline and after standard of care treatment is shedding light on immune biomarkers. Combination therapies are being tested in clinical trials and are likely to be the best approach to improving patient outcomes.  
feeds.bmj.com
over 4 years ago