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Are Patients with Atrial Fibrillation Being Optimally Treated? CME/CE

: New research indicates that primary care physicians underuse stroke and bleeding risk calculators for patients with atrial fibrillation but still aggressively prescribe warfarin.  
medscape.org
about 4 years ago
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Association between use of warfarin with common sulfonylureas and serious hypoglycemic events: retrospective cohort analysis

Study question Is warfarin use associated with an increased risk of serious hypoglycemic events among older people treated with the sulfonylureas glipizide and glimepiride?  
feeds.bmj.com
about 4 years ago
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Three-Year Major Bleeding Risk Same With Watchman or Warfarin

Patients with AF face a similar 3-year bleeding risk if they undergo left atrial appendage closure with this device or stay on long-term warfarin therapy. The CMS cautionary approach is right, two experts say.  
medscape.com
about 4 years ago
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Warfarin, Sulfonylurea Combo Ups Severe Hypoglycemia Risk

The findings suggest a unique drug-drug interaction between warfarin and glipizide/glimepiride, with the greatest hypoglycemia risk at start of warfarin treatment.  
medscape.com
about 4 years ago
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New Blood Thinner 'Antidote' to Help Doctors Move Past Warfarin

A new class of blood thinners that competes with widely used warfarin should get a boost next year when an antidote that can reverse the medications' effects in an emergency is expected to enter the market, according to top U.S. heart doctors and investors.  
medscape.com
about 4 years ago
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GI Bleeding in Patients With AF on Rivaroxaban or Warfarin

GI bleeding is a common complication of oral anticoagulation. How does the incidence of GI bleeding in AF patients taking rivaroxaban compare to those on warfarin?  
medscape.com
about 4 years ago
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Preinjury Warfarin Use and Mortality in Trauma Patients

Patients receiving warfarin therapy may be at an increased risk for mortality after sustaining a traumatic injury, a new study reports.  
medscape.com
about 4 years ago
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Less Bleeding on Rivaroxaban for AF if Fewer Concomitant Meds

Taking five or more meds is common in patients with AF, but for those taking fewer than that, the risk of bleeding was lower with rivaroxaban than with warfarin, in a new analysis of ROCKET-AF.  
medscape.com
about 4 years ago
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Outpatient Management of VTE: Which Patients Will Benefit? CME

Patients with venous thromboembolism (VTE) were traditionally treated with parenteral heparin and dose-adjusted warfarin. The arrival of the non-vitamin K oral anticoagulants (NOACs) has simplified the treatment of these patients. The goal of this activity is provide insights into the diagnosis and treatment of patients with VTE.  
medscape.org
about 4 years ago
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VTE Risk After Receiving PCC for Intracranial Hemorrhage

Prothrombin complex concentrates are commonly used for the reversal of coagulopathy in warfarin-associated intracranial hemorrhage, but there may be a greater risk for VTE in some patients.  
medscape.com
about 4 years ago
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Warfarin Reversal With 4-Factor PCC vs 3-Factor PCC

For warfarin reversal, which is the better treatment choice?  
medscape.com
about 4 years ago
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NOACs Cut Bleeding vs Warfarin Following Acute VTE

Dr Goldhaber reviews a meta-analysis he coauthored of RE-COVER trial data suggesting that new oral anticoagulants may be a better option than warfarin for treating acute VTE.  
medscape.com
about 4 years ago
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Rivaroxaban: It's Not Time to Cut the Rope, Yet

The warfarin arm of the ROCKET AF trial used a faulty INR device, leading to calls for independent verification of the study. Dr Mandrola agrees but is reassured by the real-world data on rivaroxaban.  
medscape.com
about 4 years ago
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Weight-Based Prothrombin Stops Warfarin-Induced Bleeding

Warfarin-induced coagulopathy can be reversed faster with a weight-based factor VIII inhibitor bypassing activity regimen than with fresh frozen plasma, researchers report, but mortality is similar.  
medscape.com
almost 4 years ago
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Rivaroxaban Saves Hospitals Money for VTE Admissions: Study

U.S. hospitals save money when they use the novel oral anticoagulant rivaroxaban instead of warfarin to treat patients with venous thromboembolism (VTE), a new analysis finds.  
medscape.com
almost 4 years ago
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'Well-Managed Warfarin' Good Enough in Atrial Fib: Analysis

Reopening the warfarin-vs-NOAC debate in atrial fibrillation, low complication rates on the older drug in a Swedish national cohort study impressed, but are they generalizable?  
medscape.com
almost 4 years ago
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Apr 29 Cardiology News

ECG screening in athletes, warfarin for AF, sugar-sweetened beverages, CT-induced cancer treatment costs, and night-shift work are the topics discussed by John Mandrola in this week’s podcast.  
medscape.com
almost 4 years ago
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Warfarin, AF May Each Contribute to Dementia Risk in AF

Anticoagulation clearly plays a role in long-term brain health, a researcher notes, but "we learned as well that atrial fibrillation is an additive disease state, in that it increases risk beyond anticoagulation."  
medscape.com
almost 4 years ago
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Prediction of rates of thromboembolic and major bleeding outcomes with dabigatran or warfarin among patients with atrial fibrillation: new initiator cohort study

Objectives To compare stratified event rates from randomized controlled trials with predicted event rates from models developed in observational data, and assess their ability to accurately capture observed rates of thromboembolism and major bleeding for patients treated with dabigatran or warfarin as part of routine care.  
feeds.bmj.com
over 3 years ago