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WoundHealing

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Nicotine has deleterious effects on wound healing through increased vasoconstriction

Regarding your article supporting the use of e-cigarettes,1 we wholeheartedly endorse any measure that reduces public health harm from smoking. The appropriateness of requiring patients to stop smoking before elective surgery has …  
feeds.bmj.com
about 4 years ago
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Fracture Healing: An Overview of Existing Concepts

Gain a better understanding of the fracture healing process -- and find out about the current options for managing patients with fractured bones.  
medscape.com
about 4 years ago
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Linear Facial Scars More Aesthetically Pleasing Than Zigzag Scars

The lay public has a "significantly better perception" of linear facial scars compared with zigzag scars, California-based plastic surgeons report.  
medscape.com
over 4 years ago
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Anti-vascular endothelial growth factor for control of wound healing in glaucoma surgery | Cochrane

Review question Anti-vascular endothelial growth factor (VEGF) agents versus control or mitomycin C (MMC) for the outcome of trabeculectomy.  
cochrane.org
over 4 years ago
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Surgical hand antisepsis to reduce surgical site infection | Cochrane

The inadvertent transfer of micro-organisms such as bacteria to a patient's wound site during surgery can result in a wound infection that is commonly called a surgical site infection (SSI). SSIs are one of the most common forms of health care-associated infections for surgical patients. Around 1 in 20 surgical patients develop an SSI in hospital, and this proportion rises when people go home. SSIs result in delayed wound healing, increased hospital stays, increased use of antibiotics, unnecessary pain and, in extreme cases, the death of the patient, so their prevention is a key aim for health services.  
cochrane.org
over 4 years ago
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Hyperbaric Oxygen Does Not Help Chronic Diabetic Foot Ulcers

Diabetic patients with chronic foot ulcers who received hyperbaric oxygen therapy had the same amputation risk and no better wound healing than those who received sham therapy in a new study.  
medscape.com
over 4 years ago
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'Scar-Based' VT Ablation Bests Standard Technique: VISTA

Substrate-based ablation, without need to induce VT, curtails recurrences and improves clinical outcomes, at least in expert hands, vs standard arrhythmia-guided ablation, a small trial suggests.  
medscape.com
over 4 years ago
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Inflammation and Wound Healing

Great lecture from the Chamberlain College of Nursing.  
youtube.com
over 4 years ago
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Myocardial Scars Go Undetected in Many Older Patients

Nearly 8% of older adults, who were free of clinical cardiovascular disease at baseline, had documented myocardial scars on cardiac magnetic resonance imaging at year 10, in a population-based study.  
medscape.com
over 4 years ago
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Clinically silent myocardial scars are common in middle aged and older people, study finds

Nearly 8% of middle aged and older people in the United States have myocardial scars suggestive of myocardial infarction, almost 80% of which have not been detected by electrocardiography or clinical evaluation, a study published in JAMA has found.1  
feeds.bmj.com
over 4 years ago
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Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery | Cochrane

Review question Does mitomycin C (MMC) offer any advantage in comparison to 5-Fluorouracil (5-FU) as the antimetabolite used to augment glaucoma surgery (trabeculectomy)? Does MMC help to achieve lower rates of trabeculectomy failure than 5-FU at one year postoperatively?  
cochrane.org
almost 5 years ago
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No evidence that insertion of drains after plastic and reconstructive surgery of the breast reduces complications | Cochrane

Plastic and reconstructive surgery of the breast can include breast enlargement, breast reduction, and breast reconstruction (e.g. after breast removal in breast cancer patients). Such operations are routinely performed in most hospitals. The typical duration of hospital stay is about 3 days. These operations carry a risk of complications such as wound infection, fluid accumulation, death of parts of the breast tissue, and wound healing problems, These are often minor and do not affect the end result, but can result in a longer stay in hospital and extra medical treatment. For several decades surgeons have been inserting wound drains after these procedures expecting to minimize possible complications, although it is unclear whether there is any evidence to support this. We reviewed the limited evidence available from clinical trials, and found no evidence that the use of drains improves patient outcomes in breast reduction surgery. On the contrary, the use of drains seemed to be associated with a slightly longer stay in hospital of about one day. There were no trials in people undergoing breast augmentation or reconstruction.  
cochrane.org
almost 5 years ago
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Use of Genotyping to Prevent Allopurinol Induced SCARS

This study demonstrates a pharmacogenomics approach to reducing the risk of severe cutaneous adverse reactions from allopurinol, one of the most common drugs implicated in this serious condition.  
medscape.com
almost 5 years ago
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Intralesional Cryotherapy for the Treatment of Keloid Scars

How effective is this novel technique compared with other options for keloid scar treatment? Is it a viable treatment alternative?  
medscape.com
almost 5 years ago
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Early versus delayed dressing removal for people with surgical wounds | Cochrane

Most surgical procedures involve a cut in the skin that allows the surgeon to gain access to the deeper tissues or organs. Most surgical wounds are closed fully at the end of the procedure.The surgeon covers the closed surgical wound with either a dressing or adhesive tape.The dressing can act as a physical barrier to protect the wound until the continuity of the skin in restored (within about 48 hours). It can also absorb exudate from the wound, keeping it dry and clean, and preventing bacterial contamination from the external environment. Some studies have found that the moist environment created by some dressings accelerates wound healing, although others believe that it is a disadvantage, as excessive exudate can cause softening and deterioration of the wound and surrounding healthy tissue.  
cochrane.org
almost 5 years ago
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“Black henna” tattoos can cause blistering and scarring, doctors warn

Dermatologists have warned that tattoos based on “black henna,” which are often offered at funfairs and festivals, can cause blistering, painful skin burns, and scarring.  
feeds.bmj.com
almost 5 years ago
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Alginate dressings for venous leg ulcers | Cochrane

Venous leg ulcers are a common and recurring type of chronic or complex wound which can be distressing for patients and costly to healthcare providers. Compression therapy, in the form of bandages or stockings, is considered to be the cornerstone of venous leg ulcer management. Dressings are applied underneath bandages or stockings with the aim of protecting the wound and providing a moist environment to aid healing. Alginate dressings contain substances derived from seaweed and are one of several types of wound dressings available. We evaluated the evidence from five randomised controlled trials that compared either different brands of alginate dressings, or alginate dressings with other types of dressings. In terms of wound healing, we found no good evidence to suggest that there is any difference between different brands of alginate dressings, nor between alginate dressings and hydrocolloid or plain non-adherent dressings. Adverse events were generally similar between treatment groups (but not assessed for alginate versus plain non-adherent dressings). Overall, the current evidence is of low quality. Further, good quality evidence is required before any definitive conclusions can be made regarding the use of alginate dressings in the management of venous leg ulcers.  
cochrane.org
almost 5 years ago
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New Biocompatible Hydrogel for Wound Healing, Advanced Tissue Regeneration |

Researchers at Harvard's Brigham and Women's Hospital engineered a new material that looks highly promising for use in accelerating wound healing, building  
medgadget.com
about 5 years ago
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Warmed fluids for preventing hypothermia during operations | Cochrane

During surgical operations, patients may become cold as the result of a combination of factors including the action of anaesthetic drugs, the presence of uncovered skin and the administration of cold fluids into the veins or to parts of the body where surgery is taking place to wash them. Becoming cold during surgery can be unpleasant and can cause excessive shivering after the operation. It can also cause heart problems and bleeding problems and can contribute to problems with pressure sores and wound healing and longer hospital stay. This review seeks to find out whether warming the fluids given into veins or used to wash parts of the body may prevent patients from becoming cold.  
cochrane.org
over 5 years ago
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Wounds heal faster with help from nanoparticles

When tested on the skin of mice, a new experimental therapy that uses nanoparticles to deliver an enzyme blocker cut wound healing time in half compared with no treatment.  
medicalnewstoday.com
over 5 years ago