Unexpected rapid weight gain in a patient with HIV and anorexia

A 45 year old man presented to outpatients in January 2015 with unexplained weight gain and shortness of breath. He was HIV positive (diagnosed in the early 1990s) and was on combination antiretroviral therapy (tenofovir, emtricitabine, and darunavir boosted with ritonavir). His HIV infection was...