What is the advantage of 'block and replace' regime in managing grave's disease patient?
I am now doing a thyroid surgery rotation. This morning we had a tutorial regarding management of patient with grave's disease (hyperthyroid). We were asked about what are the options that available for them. One of the participants highlighted the so called "block and replace regime" in which we are giving patient with carbimazole (block) and thyroxine (replace). The problem is, despite giving carbimazole alone, why do we need to add on thyroxine in managing hyperthyroid patient since this thyroxine might worsen the condition.