Why did a patient's Hb fall with sepsis?

I was on the renal ward round with some other medical students and the one of the patient's Hb had fallen slightly and the consultant had mentioned that it was likely secondary to their infection. I didn't understand why this would be but didn't have the courage to ask either.

Can anyone help me please?

Authored By Jess Pobbs on Monday 12th November 2012

Responses

Dr Luma Khalid
·
Posted about 7 years ago

Anemia is the commonest manifestation of inflammation. This is due to various mechanisms:

  • over expression of hepcidin (master regulaotr of iron homeostasis)
  • blood loss
  • red cell aplasia

In your patient its

Like
(1)
Respond
Hannah Brotherstone
·
Core / Specialist / Gp Trainee - Royal Devon & Exeter Hospital Wonford
·
Posted about 7 years ago

In general, a significant fall in hb would not be just explained by sepsis. For example, if someone's hb fell from 12 to 9 over 24 hours I would expect this to be related to bleeding until proved otherwise. However, when the body is under stress, s

Like
(1)
Respond
Miss Luna Ibrahim
·
Medical Student - Warwick
·
Posted about 7 years ago

Xanthogranulomatous Pyelonephritis is associated with anaemia but I haven't found an explanation of the pathological process.

Like
(0)
Respond