How does hypothyroidism cause hyperprolactinaemia?
I was just wondering how hypothyroidism causes hyperprolactinaemia?
I thought that TRH stimulates prolactin, so if TRH is low surely prolactin should be low too?
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Miss Luna Ibrahim
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Medical Student - Warwick
·
Posted over 7 years ago
TRH is high in hypothyroidism.
Dopamine has the dominant influence over prolactin secretion. Secretion of prolactin is under tonic inhibitory control by dopamine, which acts via D2-type receptors located on lactotrophs. Prolactin production can
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